Interdisciplinary Research Fellowship in NeuroAIDS

描述（由申请人提供）：本申请是神经艾滋病跨学科研究奖学金（IRFN）的第一次再竞争，该奖学金隶属于加州大学圣地亚哥分校（UCSD）的HIV神经行为研究计划（HNRP）。这个教育项目的动力来自于这样一种理念，即我们未来在解决神经艾滋病中遇到的复杂临床疾病方面的成功取决于临床导向的研究人员的可用性，这些研究人员接受了相关研究学科的培训。为此，我们采用了跨学科的研究培训模式，旨在弥合单一学科方法留下的差距。我们提议的项目将作为一个以神经艾滋病为主题的特别研究所，通过三个主要项目组成部分来强调跨学科和转化性神经艾滋病研究：一个学术教学项目，一个研究部分，以及由该领域专家的密切指导，使加州大学圣地亚哥分校和桑福德-伯纳姆医学研究所的临床前和临床导向的神经艾滋病研究人员能够发挥作用。民族阵线为每个人走向独立提供了明确的进展，以便巩固他们未来的成功。经过临床培训的个人将接受教育，从跨学科和转化的角度看待神经艾滋病研究问题，并将潜在的临床应用作为他们工作的基本终点。此外，在这次更新中，我们计划通过为寻求进入临床神经艾滋病研究的基础神经科学家试行临床培训组件来服务于我们的转化目标。IRFN研究员的研究经验将在高水平、国际公认的神经艾滋病研究人员的实验室中进行。该项目的特点是：(1)拥有长期指导研究人员成为独立研究者的优秀教师；(2)根据每个研究员的需求量身定制的研究经验，包括访问实验室的外部专家或邀请到校园进行研究；(3)固定和灵活的教学经验；(4)对项目的积极评估和监督。评估将包括设定明确的目标和结果，内部和外部小组将对IRFN的表现进行审查，以不断改进该计划。这一更新期的创新包括(1)神经生物学家和神经科学家的神经艾滋病临床素养试点培训模块；(2)选修课程，增加学员的选择和个性化；(3)利用约翰霍普金斯大学和内布拉斯加州大学NIMH神经艾滋病中心的专业知识，扩大培训资源；(4)在合作实验室进行小型实习；(5)网络沟通和组织的扩展。

DESCRIPTION (provided by applicant): This application is for the first recompetition of the Interdisciplinary Research Fellowship in NeuroAIDS (IRFN), affiliated with the HIV Neurobehavioral Research Programs (HNRP) at the University of California San Diego (UCSD). The impetus for this educational program is driven by the idea that our future success in tackling the complex clinical disorders encountered in neuroAIDS depends on the availability of clinically-oriented researchers with training across relevant research disciplines. To this end, we have followed an interdisciplinary model of research training aimed at bridging the gaps left by single discipline approaches. Our proposed program will function as a neuroAIDS-themed Special Institute emphasizing interdisciplinary and translational neuroAIDS research through three main programmatic components: an academic didactic program, a research component, and close mentoring by experts in the field, making available the talents of preclinical and clinically oriented neuroAIDS researchers at UCSD and the Sanford-Burnham Medical Research Institute. The IRFN provides a clear progression for each fellow toward independence in order to consolidate their future success. Clinically trained individuals will be educated to approach neuroAIDS research questions from an interdisciplinary and translational perspective with potential clinical applications as an essential end point of their work. Additionally, in this renewal, we plan to serve our translational goals by piloting a clinical training component for basic neuroscientists seeking to move into clinical neuroAIDS research. The research experiences of IRFN fellows will be in the laboratories of high-caliber, internationally recognized neuroAIDS researchers. The program features: (1) outstanding faculty who have a long history of mentoring researchers to become independent investigators, (2) research experiences that are tailored to each fellow's needs including access to external experts in their laboratories or invited onto campus, (3) both fixed and flexible didactic experiences, and (4) active evaluation and oversight of the program. The evaluation will include setting clear goals and outcomes, and the performance of the IRFN will be reviewed internally and by an external panel so as to constantly improve the program. Innovations for this the renewal period include (1) Pilot training module on NeuroAIDS Clinical Literacy for neurobiologists and neuroscientists; (2) Electives Program to enhance trainee choice and individuation; (3) Expanded training resources via leveraging expertise of the NIMH neuroAIDS centers at Johns Hopkins University and University of Nebraska; (4) Mini-placements in collaborating laboratories; and (5) Expansion of web-based communications and organization.