Maternal pro-inflammatory status in obesity regulates placental function

肥胖中母亲的促炎症状态调节胎盘功能

• 批准号: 8969468
• 负责人: Theresa L Powell
• 金额: $ 5.12万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-20 至 2015-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8969468
• 关键词: Maternal; pro; inflammatory; status; obesity

NA - Change of Grantee Institution

NA--受资助人制度的变更

项目成果

Protein expression of fatty acid transporter 2 is polarized to the trophoblast basal plasma membrane and increased in placentas from overweight/obese women.

• DOI: 10.1016/j.placenta.2016.02.010
• 发表时间: 2016-04
• 期刊: Placenta
• 影响因子: 3.8
• 作者: Lager S;Ramirez VI;Gaccioli F;Jang B;Jansson T;Powell TL
• 通讯作者: Powell TL

Fetus-derived DLK1 is required for maternal metabolic adaptations to pregnancy and is associated with fetal growth restriction.

• DOI: 10.1038/ng.3699
• 发表时间: 2016-12
• 期刊: Nature genetics
• 影响因子: 30.8
• 作者: Cleaton MA;Dent CL;Howard M;Corish JA;Gutteridge I;Sovio U;Gaccioli F;Takahashi N;Bauer SR;Charnock-Jones DS;Powell TL;Smith GC;Ferguson-Smith AC;Charalambous M
• 通讯作者: Charalambous M

Expression and localization of the omega-3 fatty acid receptor GPR120 in human term placenta.

• DOI: 10.1016/j.placenta.2014.04.017
• 发表时间: 2014-07
• 期刊: PLACENTA
• 影响因子: 3.8
• 作者: Lager, S.;Ramirez, V. I.;Gaccioli, F.;Jansson, T.;Powell, T. L.
• 通讯作者: Powell, T. L.

Interleukin-1β inhibits insulin signaling and prevents insulin-stimulated system A amino acid transport in primary human trophoblasts.

• DOI: 10.1016/j.mce.2013.07.013
• 发表时间: 2013-12-05
• 期刊: Molecular and cellular endocrinology
• 影响因子: 4.1
• 作者: Aye IL;Jansson T;Powell TL
• 通讯作者: Powell TL

TNF-α stimulates System A amino acid transport in primary human trophoblast cells mediated by p38 MAPK signaling.

• DOI: 10.14814/phy2.12594
• 发表时间: 2015-10
• 期刊: Physiological reports
• 影响因子: 2.5
• 作者: Aye IL;Jansson T;Powell TL
• 通讯作者: Powell TL