Expression and localization of the omega-3 fatty acid receptor GPR120 in human term placenta.
Expression and localization of the omega-3 fatty acid receptor GPR120 in human term placenta.
复制标题
DOI：
10.1016/j.placenta.2014.04.017
复制
发表时间：
2014-07
期刊：
影响因子：
3.8
通讯作者：
Powell, T. L.
中科院分区：
文献类型：
--
作者：
Lager, S.;Ramirez, V. I.;Gaccioli, F.;Jansson, T.;Powell, T. L.
Fatty acids can function as signaling molecules, acting through receptors in the cytosol or on the cell surface. G-Protein Receptor (GPR)120 is a membrane-bound receptor mediating anti-inflammatory and insulin-sensitizing effects of the omega-3 fatty acid docohexaenoic acid (DHA). GPR120 dysfunction is associated with obesity in humans. Cellular localization of GPR120 and the influence of maternal obesity on GPR120 protein expression in the placenta are unknown. Herein we demonstrate that GPR120 is predominantly expressed in the microvillous membrane (MVM) of human placenta and that the expression level of this receptor in MVM is not altered by maternal body mass index (BMI).
登录
查看更多内容
DOI：
10.1016/0005-2736(90)90157-j
发表时间：
1990-11-16
期刊：
BIOCHIMICA ET BIOPHYSICA ACTA
影响因子：
--
作者：
ILLSLEY, NP;WANG, ZQ;JACOBS, MM
通讯作者：
JACOBS, MM
影响因子：
3.8
作者：
Roberts, K. A.;Riley, S. C.;Denison, F. C.
通讯作者：
Denison, F. C.
影响因子：
3.8
作者：
Pathmaperuma, A. N.;Mana, P.;Nolan, C. J.
通讯作者：
Nolan, C. J.
影响因子：
6.1
作者：
Ericsson, A;Hamark, B;Jansson, T
通讯作者：
Jansson, T
影响因子：
3.8
作者：
Lanoix, D.;St-Pierre, J.;Vaillancourt, C.
通讯作者：
Vaillancourt, C.