Promoting Teen Health: A Web-based Intervention to Prevent Risky Driving

描述(由申请人提供)：此K99-R00应用程序准备候选人，凯瑟琳麦克唐纳，博士，为研究密集的职业发展和测试基于网络的干预措施，旨在威胁青少年的健康。这项研究计划的第一步将集中在青少年死亡和残疾的主要原因：机动车碰撞。K99的总体目标是在注意力和青少年发展、驾驶结果测量、干预开发和随机对照试验(RCT)方法方面获得高级研究培训，以开发和完善基于网络的干预措施，促进青少年新手司机的安全驾驶行为和驾驶风险降低。R00的总体目标是实施K99开发的基于网络的干预的高级版本的第一阶段RCT可行性研究。K99的具体目标是：1)接受以下方面的高级培训：注意力和青少年发展理论；创建和测试行为干预；RCT方法和先进的统计方法；结果衡量(眼睛跟踪设备、驾驶模拟器、自我报告测量和驾驶记录)；职业发展；以及负责任的研究行为；2)利用青少年焦点小组，为开发理论驱动的、基于网络的干预提供内容，以促进安全驾驶行为和降低驾驶风险；3)对基于网络的危险驾驶干预原型进行初步测试和改进(包括招募、筛选、登记、基线评估和干预交付)，这将作为R00第一阶段随机对照试验可行性研究的基础；以及4)使用初步测试和改进期间收集的数据，改进主要结果(注意力维持)和次要结果(自我报告的危险驾驶行为、驾驶表现、驾驶引用和碰撞报告)的衡量标准。K99研究培训将在两名在危险驾驶、伤害预防和RCT方面具有丰富经验的资深科学家的指导下进行。R00的具体目的是评估K99开发的基于网络的高风险驾驶干预的高级版本的可行性，在此之前90天内获得青少年司机执照。我们将：1)根据K99的数据开发基于网络的危险驾驶干预的高级版本；2)实施基于网络的危险驾驶干预的第一阶段RCT，以评估：a)招募青少年并将其随机分配到基于网络的危险驾驶干预或对照组(对照组将接受基于网络的健康饮食干预)；b)测量干预组的依从性；以及c)。在干预组和对照组中保留。作为R00的次要目标，我们将评估基于网络的危险驾驶干预在1个月和3个月时对注意力维持的主要结果、自我报告的危险驾驶行为的次要结果以及驾驶表现的影响程度；以及在6个月时对自我报告的危险驾驶行为、驾驶引用和撞车的次要结果的影响程度。R00第一阶段随机对照试验可行性研究的结果将被用作R01第二阶段疗效试验的初步数据。

DESCRIPTION (provided by applicant): This K99-R00 application prepares the candidate, Catherine McDonald, PhD, for a research-intensive career developing and testing web-based interventions directed toward threats to teen health. The first step in this program of research will focus on the leading cause of death and disability for teens: motor vehicle crashes. The overall goal of the K99 is to gain advanced research training in attention and adolescent development, driving outcome measures, intervention development, and randomized controlled trials (RCT) methodology in order to develop and refine a web-based intervention that promotes safe driving behaviors and driving risk reduction in novice teen drivers. The overall goal of the R00 is to implement a Phase I RCT feasibility study of an advanced version of the K99 developed web-based intervention. The specific aims of the K99 are: 1) To receive advanced training in: attention and adolescent developmental theory; creation and testing of behavioral interventions; RCT methodology and advanced statistical methods; outcome measures (eye tracking device, driving simulator, self-report measures and driving records); career development; and responsible conduct of research; 2) To derive content for the development of a theoretically-driven, web-based intervention to promote safe driving behaviors and driving risk reduction using focus groups with teens; 3) To conduct preliminary testing and refinement of a prototype web-based risky driving intervention (including recruitment, screening, enrollment, baseline assessment, and intervention delivery), that will serve as the foundation for the R00 Phase I RCT feasibility study; and 4) To refine the metrics for the primary outcome (attention maintenance), and secondary outcomes (self-reported risky driving behaviors, driving performance, and driving citations and crash reports) using data collected during the preliminary testing and refinement. The K99 research training will be under the guidance of two senior scientists with extensive experience in risky driving, injury prevention, and RCTs. The specific aim of the R00 is to assess the feasibility of an advanced version of the web-based risky driving intervention developed in the K99, with teen drivers licensed in the previous 90 days. We will: 1) Develop an advanced version of web-based risky driving intervention based on data from the K99; 2) Implement a Phase I RCT of the web based risky driving intervention to assess: a) Recruit and randomization of teens to web-based risky driving intervention or control group (the control group will receive a web-based intervention for healthy eating); b) Measurement of adherence among the intervention group; and c). Retention in the intervention and control groups. As a secondary aim of the R00, we will estimate effect size of the web- based risky driving intervention at 1 and 3 months on the primary outcome of attention maintenance and the secondary outcomes of self-reported risky driving behaviors, and driving performance; and at 6 months on the secondary outcomes of self-reported risky driving behaviors and driving citations and crashes. Results of the R00 Phase I RCT feasibility study will be used as preliminary data for an R01 Phase II efficacy trial.