Promoting Teen Health: A Web-based Intervention to Prevent Risky Driving

描述（由申请人提供）：此K99-R 00应用程序准备候选人，凯瑟琳·麦克唐纳博士，为研究密集型的职业生涯开发和测试基于网络的干预措施，针对青少年健康的威胁。这项研究计划的第一步将集中在青少年死亡和残疾的主要原因：机动车碰撞。K99的总体目标是在注意力和青少年发展，驾驶结果测量，干预开发和随机对照试验（RCT）方法学方面获得高级研究培训，以开发和完善基于网络的干预措施，促进青少年新手驾驶员的安全驾驶行为和驾驶风险降低。R 00的总体目标是对K99开发的基于网络的干预的高级版本实施I期RCT可行性研究。K99的具体目标是：1）接受以下方面的高级培训：注意力和青少年发展理论;行为干预措施的创建和测试; RCT方法和高级统计方法;结果测量（眼动追踪装置、驾驶模拟器、自我报告措施和驾驶记录）;职业发展;以及负责任地进行研究; 2）获得内容，用于开发理论驱动的基于网络的干预措施，以促进安全驾驶行为和使用青少年焦点小组降低驾驶风险; 3）进行初步测试和完善网上风险驾驶干预措施的原型（包括招募、筛选、入组、基线评估和干预实施），将作为R 00 I期RCT可行性研究的基础;和4）完善主要结局的指标（注意力维持）和次要结果（自我报告的危险驾驶行为，驾驶表现，以及驾驶引用和碰撞报告）使用在初步测试和改进期间收集的数据。K99研究培训将在两位资深科学家的指导下进行，他们在危险驾驶，伤害预防和RCT方面拥有丰富的经验。R 00的具体目标是评估K99中开发的基于网络的风险驾驶干预的高级版本的可行性，青少年驾驶员在过去90天内获得许可。我们将：1）根据K99的数据开发基于网络的危险驾驶干预的高级版本; 2）实施基于网络的危险驾驶干预的第一阶段RCT，以评估：a）招募并随机分配青少年到基于网络的危险驾驶干预组或对照组（对照组将接受基于网络的健康饮食干预）; B）测量干预组的依从性;以及c）。干预组和对照组的保留率。作为R 00的次要目标，我们将估计基于网络的风险驾驶干预在1个月和3个月时对注意力维持的主要结局和自我报告的风险驾驶行为和驾驶表现的次要结局的效应大小;以及在6个月时对自我报告的风险驾驶行为和驾驶引用和碰撞的次要结局的效应大小。R 00 I期RCT可行性研究的结果将用作R 01 II期疗效试验的初步数据。

DESCRIPTION (provided by applicant): This K99-R00 application prepares the candidate, Catherine McDonald, PhD, for a research-intensive career developing and testing web-based interventions directed toward threats to teen health. The first step in this program of research will focus on the leading cause of death and disability for teens: motor vehicle crashes. The overall goal of the K99 is to gain advanced research training in attention and adolescent development, driving outcome measures, intervention development, and randomized controlled trials (RCT) methodology in order to develop and refine a web-based intervention that promotes safe driving behaviors and driving risk reduction in novice teen drivers. The overall goal of the R00 is to implement a Phase I RCT feasibility study of an advanced version of the K99 developed web-based intervention. The specific aims of the K99 are: 1) To receive advanced training in: attention and adolescent developmental theory; creation and testing of behavioral interventions; RCT methodology and advanced statistical methods; outcome measures (eye tracking device, driving simulator, self-report measures and driving records); career development; and responsible conduct of research; 2) To derive content for the development of a theoretically-driven, web-based intervention to promote safe driving behaviors and driving risk reduction using focus groups with teens; 3) To conduct preliminary testing and refinement of a prototype web-based risky driving intervention (including recruitment, screening, enrollment, baseline assessment, and intervention delivery), that will serve as the foundation for the R00 Phase I RCT feasibility study; and 4) To refine the metrics for the primary outcome (attention maintenance), and secondary outcomes (self-reported risky driving behaviors, driving performance, and driving citations and crash reports) using data collected during the preliminary testing and refinement. The K99 research training will be under the guidance of two senior scientists with extensive experience in risky driving, injury prevention, and RCTs. The specific aim of the R00 is to assess the feasibility of an advanced version of the web-based risky driving intervention developed in the K99, with teen drivers licensed in the previous 90 days. We will: 1) Develop an advanced version of web-based risky driving intervention based on data from the K99; 2) Implement a Phase I RCT of the web based risky driving intervention to assess: a) Recruit and randomization of teens to web-based risky driving intervention or control group (the control group will receive a web-based intervention for healthy eating); b) Measurement of adherence among the intervention group; and c). Retention in the intervention and control groups. As a secondary aim of the R00, we will estimate effect size of the web- based risky driving intervention at 1 and 3 months on the primary outcome of attention maintenance and the secondary outcomes of self-reported risky driving behaviors, and driving performance; and at 6 months on the secondary outcomes of self-reported risky driving behaviors and driving citations and crashes. Results of the R00 Phase I RCT feasibility study will be used as preliminary data for an R01 Phase II efficacy trial.