Developing Biomedical Research Infrastructure at UTB/TSC

在 UTB/TSC 开发生物医学研究基础设施

• 批准号: 8465149
• 负责人: Michael W Lehker
• 金额: $ 44.01万
• 依托单位: UNIV/TEXAS BROWNSVILLE & SOUTHMOST COLL
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-11-08 至 2015-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8465149
• 关键词: Address; Affect; Biomedical Research; Clinical Research; Communities; Computers and Advanced Instrumentation; Continuing Education; Depressed mood; Development Plans; Disease; Education; Educational Curriculum; Environment; Faculty; Five-Year Plans; Future; Health; Health Occupations; Hispanics; Image; Institution; Investigation; Knowledge; Minority; Minority-Serving Institution; Mission; Population; Positioning Attribute; Preparation; Research; Research Infrastructure; Research Personnel; Research Training; Resource Development; Science; Scientist; Services; Statutes and Laws; Strategic Planning; Students; Sustainable Development; System; Texas; Training; Training Activity; Underserved Population; United States; United States National Institutes of Health; Universities; career development; college; cultural values; health disparity; improved; infrastructure development; meetings; member; programs; research and development; research facility; skills

DESCRIPTION (Provided by the Applicant): The University of Texas at Brownsville and Texas Southmost College (UTB/TSC) is a Hispanic-serving institution that resides in the southernmost tip of Texas with a predominantly Hispanic, poor, and underserved population. The university has made remarkable progress over the last ten years towards developing competitive research programs. UTB/TSC seeks to continue the university's momentum in research infrastructure development. UTB/TSC has prioritized biomedical research for the investigation of diseases that affect this population and is positioned to become the leading health related research institution that addresses health disparities and the growing health needs of the region. The continuation of the RIMI program will provide the mechanism for UTB/TSC to accelerate the implementation of the university's research plans through enhancing research facilities and the research environment for students and faculty. The five-year plan emphasizes four core functions to create an active and supportive research environment for faculty and future scientists. These cores include 1) strengthening the research infrastructure that sustains and enhances biomedical research at UTB/TSC; 2) enhancing the research training capacity to further develop junior research scientists through career development planning; 3) developing curricular changes and student training activities that will improve student preparation in biomedical science research and health professions, and 4) enhancing the imaging research facilities through the acquisition of advanced instrumentation. The RIMI project will develop a cadre of biomedical and clinical research scientists with the skills and knowledge to engage in leading edge research that contributes to the reduction of health disparities. The development of sustainable biomedical research at UTB/TSC will create knowledge, impact developing junior faculty and students, generate significant resources for the development of research at our minority institution, and contribute to eliminating health disparities in the United States.

描述（由申请人提供）：德克萨斯大学布朗斯维尔大学和德克萨斯大学最南学院（UTB/TSC）是西班牙裔服务机构，位于德克萨斯州最南端的西班牙裔，主要是西班牙裔，贫穷和服务不足的人口。在过去的十年中，该大学在制定竞争性研究计划方面取得了惊人的进步。 UTB/TSC试图继续大学在研究基础设施发展方面的势头。 UTB/TSC已将生物医学研究优先考虑影响该人群的疾病，并有望成为解决该地区健康差异和日益增长的健康需求的领先健康相关研究机构。 RIMI计划的延续将为UTB/TSC提供一种机制，以通过增强研究设施和学生的研究环境来加速大学的研究计划 和教师。五年计划强调了四个核心职能，以为教师和未来的科学家创造一个积极而支持的研究环境。这些核心包括1）加强在UTB/TSC上维持和增强生物医学研究的研究基础设施； 2）增强研究培训能力，通过职业发展计划进一步发展初级研究科学家； 3）开发课程变化和学生培训活动，以改善生物医学科学研究和卫生专业的学生准备，以及4）通过获取高级仪器来增强成像研究设施。 RIMI项目将开发一群生物医学和临床研究科学家的干部，具有参与前沿研究的技能和知识，这有助于减少健康差异。 UTB/TSC的可持续生物医学研究的发展将创造知识，影响开发初级教师和学生，为我们少数民族的研究开发大量资源，并为消除美国的健康差异做出贡献。

项目成果

Small molecule inhibitors of Bacillus anthracis protective antigen proteolytic activation and oligomerization.

• DOI: 10.1021/jm300804e
• 发表时间: 2012-09-27
• 期刊: JOURNAL OF MEDICINAL CHEMISTRY
• 影响因子: 7.3
• 作者: Wein, Alexander N.;Williams, Brian N.;Liu, Shihui;Ermolinsky, Boris;Provenzano, Daniele;Abagyan, Ruben;Orry, Andrew;Leppla, Stephen H.;Peredelchuk, Michael
• 通讯作者: Peredelchuk, Michael

Septo-hippocampal networks in chronic epilepsy.

• DOI: 10.1016/j.expneurol.2009.12.010
• 发表时间: 2010-03
• 期刊: Experimental neurology
• 影响因子: 5.3
• 作者: García-Hernández A;Bland BH;Facelli JC;Colom LV
• 通讯作者: Colom LV

Deficit of Kcnma1 mRNA expression in the dentate gyrus of epileptic rats.

• DOI: 10.1097/wnr.0b013e3283094bb6
• 发表时间: 2008-08-27
• 期刊: Neuroreport
• 影响因子: 1.7
• 作者: Ermolinsky B;Arshadmansab MF;Pacheco Otalora LF;Zarei MM;Garrido-Sanabria ER
• 通讯作者: Garrido-Sanabria ER

Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy.

颞叶癫痫毛果芸香碱模型中 BK 通道表达下调。

• DOI: 10.1016/j.brainres.2008.01.017
• 发表时间: 2008
• 期刊: Brain research
• 影响因子: 2.9
• 作者: PachecoOtalora,LuisF;Hernandez,EderF;Arshadmansab,MassoudF;Francisco,Sebastian;Willis,Michael;Ermolinsky,Boris;Zarei,Masoud;Knaus,Hans-Guenther;Garrido-Sanabria,EmilioR
• 通讯作者: Garrido-Sanabria,EmilioR

Epileptiform activity in the limbic system.

• DOI: 10.2741/s172
• 发表时间: 2011-01-01
• 期刊: Frontiers in bioscience (Scholar edition)
• 作者: Oliveira, Mauro Schneider;Pacheco, Luis Fernando;Garrido-Sanabria, Emilio Rafael
• 通讯作者: Garrido-Sanabria, Emilio Rafael