CANCER CENTER SUPPORT GRANT

癌症中心支持补助金

• 批准号: 8328889
• 负责人: GEROLD BEPLER
• 金额: $ 254.76万
• 依托单位: WAYNE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-08 至 2015-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8328889
• 关键词: Achievement; Address; Affect; African American; Ambulatory Care; Anti-Retroviral Agents; Area; Barbara Ann Karmano Cancer Institute; Basic Science; Behavioral; Biological Markers; Biometry; Breast; Breast Cancer Risk Factor; Cancer Biology; Cancer Burden; Cancer Center; Cancer Center Support Grant; Cancer Control; Cancer Hospital; Cancer Vaccines; Cell Line; Clinic; Clinical; Clinical Research; Clinical Services; Clinical Trials; Clinical Trials Cooperative Group; Collaborations; Communication; Communities; Comprehensive Cancer Center; Computational Biology; Country; Development; Developmental Therapeutics Program; Early Diagnosis; Early treatment; Epidemiologic Studies; Erinaceidae; Erlotinib; Fostering; Functional Imaging; Funding; Future; Genomics; Graduate Education; Grant; Growth; Head and Neck Cancer; Health system; Home environment; Hormone Responsive; Hospitals; Image Cytometry; Imaging technology; In Vitro; Institutes; Instruction; Intervention; Lead; MCF7 cell; Malignant Neoplasms; Malignant neoplasm of anus; Malignant neoplasm of esophagus; Michigan; Microscopy; Minority; Modeling; Molecular; Molecular Biology; Molecular Epidemiology; Molecular Genetics; Monitor; Morbidity - disease rate; Nonionizing Radiation; Ohio; Paclitaxel; Paper; Patient Care; Patient Education; Peer Review; Peptide Hydrolases; Pharmaceutical Preparations; Pharmacology; Phase I Clinical Trials; Population; Population Heterogeneity; Population Research; Population Study; Positron-Emission Tomography; Premalignant; Prevention; Proteomics; Publications; Publishing; Recruitment Activity; Request for Applications; Research; Research Personnel; Resource Sharing; Resources; Risk Assessment; Rural; Scientist; Seminal; Services; System; Tracer; Translational Research; Ultrasonography; United States; Universities; Vertebral column; Vision; Zidovudine; anticancer research; base; biobank; breast density; breast lesion; cancer immunotherapy; epidemiology study; inhibitor/antagonist; lapatinib; malignant breast neoplasm; medical schools; medically underserved population; member; metropolitan; mortality; new technology; novel; oncology; operation; outreach; programs; racial and ethnic; social; socioeconomics; suburb; success; technology development; tomography; tumor

DESCRIPTION (provided by applicant): This application requests renewal for years 29-33 of the NCI Cancer Center Support Grant (CCSG) for the Barbara Ann Karmanos Cancer Institute (KCI) at Wayne State University. The Programs of KCI reflect the cancer needs of the greater Metropolitan Detroit area. This is an industrialized, urban and ethnically diverse community with a disproportionate number of medically disadvantaged, low socio-economic citizens. KCI has a long-standing and extensive commitment to both research and clinical services that address the prevention, early detection and treatment of cancer, particularly of African Americans who carry a disproportionate cancer burden. This application requests support for five Programs, ten Cores, Developmental Funds, five Staff Investigators, and related administrative support. KCI's established Programs are Breast Cancer Biology; Developmental Therapeutics; Molecular Biology and Genetics; Population Studies and Disparities Research, and Proteases and Cancer. Our Programs are organized to integrate basic, translational, and clinical research with population research-based cancer control activities. Additionally, CCSG support is requested for ten Cores, in Behavioral and Field Research; Biorepository; Epidemiology Research; Genomics; Microscopy, Imaging and Cytometry Resources; Pharmacology; Proteomics; Systems and Computational Biology; Biostatistics; and Clinical Trials Office. KCI fosters inter-disciplinary interactions and collaborations, utilizes CCSG Developmental Funds to recruit new investigators, encourages translational research Programs, and develops new Shared Resources (Cores) to support KCI members. Research growth continues, as demonstrated by increases in the number of publications and the recruitment of internationally recognized scientists. KCI has 235 members, 170 are Scientific Members and 65 are Clinical Members representing 40 departments and institutes from Wayne State University, Henry Ford Health System, University of Windsor, and Michigan State University. KCI's total annual direct grant funding is $63,296,703 of which $42,441,739 is peer reviewed funding. Of the peer reviewed funding, 6 1 % is from NCI. Over the last grant period, members' published 2,980 papers, 38% and 35% were intra- and inter-programmatic, respectively and 24% were both intra- and inter-programmatic.

描述（由申请人提供）：本申请申请韦恩州立大学芭芭拉·安·卡尔马诺斯癌症研究所（KCI）的NCI癌症中心支持补助金（CCSG）的29-33年续期。KCI的项目反映了底特律大都会地区的癌症需求。这是一个工业化、城市和种族多样化的社区，医疗条件不利、社会经济地位低下的公民数量不成比例。KCI长期致力于研究和临床服务，以解决癌症的预防、早期发现和治疗，特别是非洲裔美国人，他们背负着不成比例的癌症负担。