Post Graduate Program in Cutaneous Biology

皮肤生物学研究生课程

• 批准号: 8267973
• 负责人: ROBERT M LAVKER
• 金额: $ 12.83万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-01 至 2017-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8267973
• 关键词: Biology; Cutaneous; programs

DESCRIPTION (provided by applicant): This post-doctoral fellowship program is designed to train dermatologists and basic scientists who desire a thorough grounding in one or more of the following broad disciplines: biochemistry, cell biology, enzymology, genetics, immunology, microbiology, molecular biology, morphology, and photobiology. The basic aim of training is to provide an environment in which outstanding fellows can learn to be independent researchers in cutaneous biology. This goal will be accomplished through a mentored laboratory experience coupled with an intensive educational enrichment program. The thrust of our postdoctoral research training is that committed individuals spend a minimum of 2 years in a basic research laboratory and receive general and specialized instruction in the techniques of the laboratory by working on a well conceived problem with one or more mentors. During this time they will also be instructed in critical thinking, writing and presentation skills, the peer-review process and th responsible conduct of research. Trainees can choose research areas under the mentorship of senior scientists, either in the Department of Dermatology or in other departments (Cell and Molecular Biology, Chemistry, Medicine, Microbiology and Immunology, Pathology, or Pediatrics). Examples of research are: cell adhesion, cell motility, cell proliferation and differentiation, cutaneous immunology, epithelial stem cell biology, experimental carcinogenesis, extracellular matrix biology, inflammation, RNA silencing, signal transduction, wound healing and viral pathogenesis. The training sites on the Chicago and Evanston campuses provide state-of-the-art resources and facilities within individual laboratories and shared resources, including the Skin Disease Research Center. In addition to "in lab training", a major focal point of the program centers around educational enrichment activities. Trainees will attend and participate in seminar series such as the "Bench to Bedside" lecture series, the Epithelial Biology Group, basic science journal clubs, laboratory "Works in Progress" meetings, a Wound Healing and Fibrosis series and the Grand Rounds lecture series organized through the Department of Dermatology. Our first priority will be to enroll physician/scientists who have completed their residency in dermatology and hold either an M.D./Ph.D. or an M.D. degree. We will also consider Ph.D. scientists. Candidates will be carefully selected to include only those with outstanding academic records, who show considerable interest and commitment to cutaneous research and desire to continue in academic dermatology. Given the sustained strengthening of the Department of Dermatology, including the awarding of a Skin Disease Research Center, and a dramatic increase in dermatology residents with M.D./Ph.D. degrees, the time is right for formal support of a Post Graduate Training Program in Cutaneous Biology. PUBLIC HEALTH RELEVANCE: The continued increase in sophistication of investigative techniques has revealed the vast complexity of skin and skin disorders, and has led to novel therapeutic approaches to manage disorders with cutaneous manifestations. To effectively harness such knowledge and bring it to the bedside, there is a dramatic need for well-trained physician/scientists and/or scientists with a thorough grounding in both bench and translational research to serve as the next generation of academicians in dermatology and cutaneous biology. Post Graduate Training Programs in Cutaneous Biology provide a means to develop these academic dermatologists.

描述（由申请人提供）：该博士后奖学金计划旨在培训皮肤科医生和基础科学家，他们希望在以下一个或多个广泛学科中有全面的基础：生物化学、细胞生物学、酶学、遗传学、免疫学、微生物学、分子生物学、形态学和光生物学。培训的基本目的是提供一个环境，让优秀的研究员能够学习成为皮肤生物学的独立研究人员。这一目标将通过指导实验室经验和强化教育强化计划来实现。我们的博士后研究培训的主旨是，有奉献精神的个人在基础研究实验室至少呆两年，并通过与一位或多位导师一起解决一个精心设计的问题，接受实验室技术的一般和专业指导。在此期间，他们还将接受批判性思维、写作和演讲技巧、同行评审过程以及负责任的研究行为方面的指导。学员可以在皮肤科或其他科室（细胞和分子生物学、化学、医学、微生物学和免疫学、病理学或儿科）的资深科学家的指导下选择研究领域。研究实例包括：细胞粘附、细胞运动、细胞增殖和分化、皮肤免疫学、上皮干细胞生物学、实验性致癌作用、细胞外基质生物学、炎症、RNA沉默、信号转导、伤口愈合和病毒发病机制。芝加哥和埃文斯顿校区的培训地点在各个实验室和共享资源内提供最先进的资源和设施，包括皮肤病研究中心。除了“实验室培训”之外，该计划的一个主要重点是教育丰富活动。学员将出席并参加一系列研讨会，例如“从工作台到床边”讲座系列、上皮生物学小组、基础科学期刊俱乐部、实验室“正在进行的工作”会议、伤口愈合和纤维化系列以及通过皮肤科组织的大查房讲座系列。我们的首要任务是招募已完成皮肤科住院医师实习并拥有医学博士/博士学位的医生/科学家。或医学博士学位。我们还将考虑博士学位。科学家。候选人将经过精心挑选，只包括那些具有杰出学术记录、对皮肤研究表现出极大兴趣和承诺并希望继续从事皮肤病学学术研究的人。鉴于皮肤科的持续加强，包括授予皮肤病研究中心，以及拥有医学博士/博士学位的皮肤科住院医生的急剧增加。学位，是时候正式支持皮肤生物学研究生培训计划了。 公共卫生相关性：研究技术的不断成熟揭示了皮肤和皮肤疾病的巨大复杂性，并催生了治疗皮肤表现疾病的新治疗方法。为了有效地利用这些知识并将其应用于临床，迫切需要训练有素的医生/科学家和/或在实验室研究和转化研究方面有全面基础的科学家，以成为皮肤病学和皮肤生物学领域的下一代院士。皮肤生物学研究生培训项目为培养这些学术皮肤科医生提供了一种手段。