DEVELOPMENT AND EVALUATION OF A SMOKING MODULE FOR PROMIS

描述(由申请者提供)：患者报告结果测量信息系统(PROIS)是NIH路线图倡议的一项为期5年的合作研究计划，旨在开发、评估和标准化题库，以衡量与一系列慢性疾病(例如癌症、抑郁症、关节炎)相关的关键健康状况领域。这一倡议的最终目标是生产临床研究工具，如计算机化自适应测试和非自适应评估，并使这些工具广泛用于临床研究和临床实践。PROMIS的第一阶段共开发了6个领域的11个题库，并使研究人员可以通过一个互动网站获取对这些领域的测量。已确定但尚未开发的最重要的领域之一是吸烟领域。这个拟议项目的目标是开发、评估和标准化题库，以评估吸烟行为和与吸烟相关的生物心理社会结构，并将该题库纳入PROMIS框架。吸烟几乎与所有健康状况有关，并对发病率和死亡率有重大影响。增加吸烟域是PROMIS框架开发的关键下一步，这将极大地扩大其实用性和适用性。该项目有四个具体目标：目标1：确定吸烟领域的组成部分并开发初始项目库；目标2：通过分析调查响应数据来评估项目库的测量性质；目标3：通过分析吸烟和其他促进领域得分数据提供关于吸烟者健康状况的描述性信息；目标4：研究吸烟以及与吸烟相关的生物心理社会结构对寻求综合医疗诊所治疗的个人的健康状况和短期康复的影响。到项目结束时，我们将开发、评估和测试心理健康题库的初步有效性，该题库可以形成吸烟行为和与吸烟相关的生物心理社会结构的标准化评估的基础。将这一题库纳入现有的PROMIS框架将大大有助于研究吸烟各方面与其他与健康有关的结果之间的关系。

DESCRIPTION (provided by applicant): The Patient Reported Outcomes Measurement Information System (PROMIS), an NIH Roadmap initiative, is a 5-year cooperative program of research designed to develop, evaluate, and standardize item banks to measure key health status domains relevant to a range of chronic medical conditions (e.g., cancer, depression, arthritis). The ultimate goal of this initiative is to produce clinical research tools, such as computerized-adaptive testing and non-adaptive assessments, and to make these tools broadly available for use in clinical research and clinical practice. The first phase of PROMIS has developed a total of 11 item banks across 6 domains and has made measurement of these domains accessible to researchers through an interactive website. One of the most significant areas identified but not yet developeed is the domain of cigarette smoking. The goal of this proposed project is to develop, evaluate, and standardize an item bank to assess cigarette smoking behavior and biopsychosocial constructs associated with smoking, and incorporate this item bank into the PROMIS framework. Smoking is relevant to nearly all health conditions and has a significant impact on morbidity and mortality. The addition of a smoking domain is a critical next step in the development of the PROMIS framework that would do much to expand its utility and applicability. The project has four specific aims: AIM 1: Identify smoking domain components and develop initial item pool; AIM 2: Evaluate measurement properties of item pool through analysis of survey response data; AIM 3: Provide descriptive information about the health status of smokers through analysis of smoking and other PROMIS domain score data; AIM 4: Examine the impact of smoking and the biopsychosocial constructs associated with smoking on health status and short term recovery among individuals seeking care at a general medical clinic. By the end of the project period, we will have developed, evaluated, and tested the initial validity for a psychometrically sound item bank that can form the basis for standardized assessment of smoking behavior and biopsychosocial constructs associated with smoking. The integration of this item bank into the existing PROMIS framework will do much to facilitate the study of associations between aspects of smoking and other health-related outcomes.