Regular HIV Testing among At-Risk Latino Men

对高危拉丁裔男性进行定期艾滋病毒检测

• 批准号: 8658536
• 负责人: Laura R Glasman
• 金额: $ 22.82万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-21 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8658536
• 关键词: Accounting; Address; Affect; African American; American; Behavior; Belief; Caring; Centers for Disease Control and Prevention (U.S.); Characteristics; Communication; Early Diagnosis; Epidemic; Face; Fostering; Foundations; Fright; HIV; HIV Infections; HIV Seropositivity; HIV diagnosis; HIV risk; Health; Health Services Accessibility; Healthcare; High Prevalence; Homosexuality; Human immunodeficiency virus test; Incidence; Individual; Infection; Intervention; Interview; Latino; Legal; Life; Link; Outcome; Participant; Persons; Positioning Attribute; Prevalence; Prevention; Preventive; Procedures; Quality of life; Randomized Controlled Trials; Recruitment Activity; Research; Resources; Rewards; Risk; Risk Assessment; Risk Behaviors; Risk Reduction; Safety; Services; Sexual Partners; Social Network; Societies; Source; Test Result; Testing; Time; Training; Work; antiretroviral therapy; behavior test; ethnic minority population; experience; follow-up; high risk; improved; inattention; meetings; member; men; men who have sex with men; mortality; peer; prevent; public health relevance; randomized trial; response; screening; sex; sexual minority; social; social group; success; treatment adherence

DESCRIPTION (provided by applicant): Regular HIV Testing among At-risk Latino Men This R34 application proposes 3 years of research to pilot an intervention to promote regular HIV testing and safer behavior among sociocentric networks of Latino men at risk for HIV. In the US, 20% of the 1.1 million individuals living with HIV are unaware of their HIV status. Undiagnosed HIV positive persons cannot benefit from early access to treatments that increase quality of life and reduce infectivity. Encouraging HIV testing and providing treatment to those testing positive can improve the health of HIV infected persons and reduce HIV incidence. To obtain the benefits of early diagnosis, CDC suggest that persons at higher risk for HIV get tested regularly twice a year. Despite the many strategies to encourage HIV testing, to our knowledge, there are no strategies to promote regular HIV testing among any group at risk for HIV. In the US, the HIV epidemic is largely concentrated in clusters of individuals with high HIV prevalence and undiagnosed infections. Latino men who have sex with men (LMSM) comprise many of these clusters. LMSM experience challenges that make it difficult to engage them in preventive care, including disconnection from services, norms than condemn homosexuality, and erroneous risk assessments such as the belief that sex within their ingroup is less risky. LMSM rely on other LMSM who are sources of advice and partially shield them from the double jeopardy of being a sexual and ethnic minority. Network approaches can use these relationships to reach high risk LMSM and foster norms that reduce their collective risk. This proposal intends to use networks to promote regular HIV testing and risk reduction among LMSM. We will recruit three-ring networks of LMSM and identify their ties. Well positioned LMSM will inform and motivate their peers for risk reduction, and be trained to be bridges to prevention resources, provide tailored prompts to testing, and reward HIV testing behaviors to encourage repetition. This proposal seeks to (1) conduct research to tailor recruitment and intervention procedures to networks of LMSM, (2) demonstrate the feasibility of recruiting 3-ring sociocentric networks of LMSM, train key members to promote regular testing and risk reduction in their networks, and assess network characteristics and outcomes at six- and 12-month follow up; and (3) evaluate the acceptability of the intervention among participants. Following formative work, we will invite socially central LMSM to initiate recruitment of five three- ring networks of LMSM (N H 150). We will test men for HIV and recommend that they get tested regularly. We will invite key members of three randomly selected networks to a six-session training to promote regular HIV testing and risk reduction in their networks. We will assess networks and intervention outcomes at six- and 12- month follow-ups. At the last follow up, we will interview participants to elicit their experiences and identify effective communication strategies. This study will evaluate the feasibility of a strategy to promote regular testing and risk reduction among networks that account for a large number of new HIV cases. If successful, this project will inform a randomized trial with an 18-month follow up to evaluate the efficacy of this approach.

描述（由申请人提供）：有风险的拉丁裔男性中的定期艾滋病毒检测此R34申请提出了3年的研究，以试点干预，以促进定期艾滋病毒检测和更安全的行为之间的社会中心网络的拉丁裔男性在艾滋病毒的风险。在美国，110万艾滋病毒感染者中有20%不知道自己的艾滋病毒状况。未确诊的艾滋病毒阳性者不能从抢先体验治疗中获益，因为这种治疗可以提高生活质量和减少传染性。鼓励进行艾滋病毒检测并为检测呈阳性的人提供治疗，可以改善艾滋病毒感染者的健康，降低艾滋病毒发病率。为了获得早期诊断的好处，CDC建议艾滋病毒高危人群每年定期进行两次检测。尽管有许多鼓励艾滋病毒检测的战略，但据我们所知，没有任何战略促进在任何艾滋病毒高危群体中定期进行艾滋病毒检测。在美国，艾滋病毒流行主要集中在艾滋病毒流行率高和未确诊感染的人群中。与男性发生性关系的拉丁裔男性（LMSM）包括许多这些集群。LMSM经历的挑战使他们难以参与预防性护理，包括与服务脱节，谴责同性恋的规范，以及错误的风险评估，例如认为其内部群体内的性行为风险较低。LMSM依赖于其他LMSM，他们是咨询的来源，并部分地保护他们免受性少数和种族少数的双重危险。网络方法可以利用这些关系，以达到高风险的LMSM和促进规范，减少他们的集体风险。该提案旨在利用网络促进LMSM中的定期艾滋病毒检测和降低风险。我们将招募LMSM的三环网络，并确定他们的联系。定位良好的LMSM将告知和激励他们的同龄人减少风险，并接受培训，成为预防资源的桥梁，提供量身定制的检测提示，并奖励艾滋病毒检测行为，以鼓励重复。该提案旨在（1）开展研究，以针对LMSM网络制定招募和干预程序，（2）证明招募LMSM三环社会中心网络的可行性，培训主要成员，以促进其网络中的定期测试和风险降低，并在6个月和12个月的随访中评估网络特征和成果;（3）评估干预措施在参与者中的可接受性。在形成性工作之后，我们将邀请社会中心LMSM开始招募LMSM的五个三环网络（NH 150）。我们将对男性进行艾滋病毒检测，并建议他们定期接受检测。我们将邀请三个随机选择的网络的主要成员参加六期培训，以促进其网络中的定期艾滋病毒检测和减少风险。我们将在6个月和12个月的随访中评估网络和干预结果。在最后的跟进中，我们将采访参与者，以了解他们的经验，并确定有效的沟通策略。这项研究将评估一项战略的可行性，以促进在有大量艾滋病毒新病例的网络中进行定期检测和减少风险。如果成功，该项目将通知一项随机试验，随访18个月，以评估这种方法的有效性。