Regular HIV Testing among At-Risk Latino Men

对高危拉丁裔男性进行定期艾滋病毒检测

• 批准号: 8895411
• 负责人: Laura R Glasman
• 金额: $ 21.26万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-21 至 2017-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8895411
• 关键词: Accounting; Address; Affect; African American; American; Behavior; Belief; Caring; Centers for Disease Control and Prevention (U.S.); Characteristics; Communication; Early Diagnosis; Epidemic; Face; Fostering; Foundations; Fright; HIV; HIV Infections; HIV Seropositivity; HIV diagnosis; HIV risk; Health; Health Services Accessibility; Healthcare; High Prevalence; Homosexuality; Human immunodeficiency virus test; Incidence; Individual; Infection; Intervention; Interview; Latino; Legal; Life; Link; Outcome; Participant; Persons; Positioning Attribute; Prevalence; Prevention; Preventive; Procedures; Quality of life; Randomized Controlled Trials; Recruitment Activity; Research; Resources; Rewards; Risk; Risk Assessment; Risk Behaviors; Risk Reduction; Safety; Services; Sexual Partners; Social Network; Societies; Source; Test Result; Testing; Time; Training; Work; antiretroviral therapy; behavior test; ethnic minority population; experience; follow-up; high risk; improved; inattention; meetings; member; men; men who have sex with men; mortality; peer; prevent; public health relevance; randomized trial; response; screening; sex; sexual minority; social; social group; success; treatment adherence

DESCRIPTION (provided by applicant): Regular HIV Testing among At-risk Latino Men This R34 application proposes 3 years of research to pilot an intervention to promote regular HIV testing and safer behavior among sociocentric networks of Latino men at risk for HIV. In the US, 20% of the 1.1 million individuals living with HIV are unaware of their HIV status. Undiagnosed HIV positive persons cannot benefit from early access to treatments that increase quality of life and reduce infectivity. Encouraging HIV testing and providing treatment to those testing positive can improve the health of HIV infected persons and reduce HIV incidence. To obtain the benefits of early diagnosis, CDC suggest that persons at higher risk for HIV get tested regularly twice a year. Despite the many strategies to encourage HIV testing, to our knowledge, there are no strategies to promote regular HIV testing among any group at risk for HIV. In the US, the HIV epidemic is largely concentrated in clusters of individuals with high HIV prevalence and undiagnosed infections. Latino men who have sex with men (LMSM) comprise many of these clusters. LMSM experience challenges that make it difficult to engage them in preventive care, including disconnection from services, norms than condemn homosexuality, and erroneous risk assessments such as the belief that sex within their ingroup is less risky. LMSM rely on other LMSM who are sources of advice and partially shield them from the double jeopardy of being a sexual and ethnic minority. Network approaches can use these relationships to reach high risk LMSM and foster norms that reduce their collective risk. This proposal intends to use networks to promote regular HIV testing and risk reduction among LMSM. We will recruit three-ring networks of LMSM and identify their ties. Well positioned LMSM will inform and motivate their peers for risk reduction, and be trained to be bridges to prevention resources, provide tailored prompts to testing, and reward HIV testing behaviors to encourage repetition. This proposal seeks to (1) conduct research to tailor recruitment and intervention procedures to networks of LMSM, (2) demonstrate the feasibility of recruiting 3-ring sociocentric networks of LMSM, train key members to promote regular testing and risk reduction in their networks, and assess network characteristics and outcomes at six- and 12-month follow up; and (3) evaluate the acceptability of the intervention among participants. Following formative work, we will invite socially central LMSM to initiate recruitment of five three- ring networks of LMSM (N H 150). We will test men for HIV and recommend that they get tested regularly. We will invite key members of three randomly selected networks to a six-session training to promote regular HIV testing and risk reduction in their networks. We will assess networks and intervention outcomes at six- and 12- month follow-ups. At the last follow up, we will interview participants to elicit their experiences and identify effective communication strategies. This study will evaluate the feasibility of a strategy to promote regular testing and risk reduction among networks that account for a large number of new HIV cases. If successful, this project will inform a randomized trial with an 18-month follow up to evaluate the efficacy of this approach.

描述（由申请人提供）：对高危拉丁裔男性进行定期 HIV 检测 该 R34 申请提出了为期 3 年的研究，以试点一项干预措施，以促进以社会为中心的高危拉丁裔男性网络中的定期 HIV 检测和更安全的行为。在美国，110 万艾滋病毒感染者中有 20% 不知道自己的艾滋病毒感染状况。未确诊的艾滋病毒阳性者无法从早期获得提高生活质量和降低传染性的治疗中受益。鼓励艾滋病毒检测并为检测呈阳性的人提供治疗可以改善艾滋病毒感染者的健康并降低艾滋病毒发病率。为了获得早期诊断的好处，疾病预防控制中心建议艾滋病毒高危人群每年定期接受两次检测。尽管有许多鼓励艾滋病毒检测的策略，但据我们所知，没有任何策略可以促进任何艾滋病毒高危人群定期进行艾滋病毒检测。在美国，艾滋病毒流行主要集中在艾滋病毒感染率高和未确诊感染的人群中。与男性发生性关系的拉丁裔男性 (LMSM) 包括许多此类群体。 LMSM 面临着让他们难以参与预防性护理的挑战，包括服务中断、谴责同性恋的规范以及错误的风险评估，例如认为群体内的性行为风险较小。 LMSM 依赖其他 LMSM 提供建议，并部分保护他们免受性少数和种族少数的双重危险。网络方法可以利用这些关系来达到高风险 LMSM 并培育降低集体风险的规范。该提案旨在利用网络促进 LMSM 定期进行艾滋病毒检测并降低风险。我们将招募 LMSM 的三环网络并确定它们的联系。定位良好的 LMSM 将告知并激励同行降低风险，并接受培训，成为预防资源的桥梁，提供量身定制的检测提示，并奖励 HIV 检测行为以鼓励重复。该提案旨在 (1) 开展研究，为 LMSM 网络定制招募和干预程序，(2) 论证招募 LMSM 3 环社会中心网络的可行性，培训关键成员以促进其网络的定期测试和风险降低，并在 6 个月和 12 个月的随访中评估网络特征和结果； (3) 评估参与者对干预措施的可接受性。在形成工作之后，我们将邀请社会中心 LMSM 启动 LMSM 的五个三环网络的招募（N H 150）。我们将对男性进行艾滋病毒检测，并建议他们定期接受检测。我们将邀请三个随机选择的网络的主要成员参加为期六次的培训，以促进其网络中的定期艾滋病毒检测和降低风险。我们将在 6 个月和 12 个月的随访中评估网络和干预结果。在最后的跟进中，我们将采访参与者以获取他们的经验并确定有效的沟通策略。这项研究将评估一项战略的可行性，以促进在存在大量艾滋病毒新发病例的网络中进行定期检测和降低风险。如果成功，该项目将为一项随机试验提供信息，并进行 18 个月的随访，以评估该方法的有效性。