Beliefs and decision-making about HPV vaccination among young men who have sex wi

有性行为的年轻男性对 HPV 疫苗接种的信念和决策

• 批准号: 8522631
• 负责人: Christopher W. Wheldon
• 金额: $ 3.26万
• 依托单位: UNIVERSITY OF SOUTH FLORIDA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-01 至 2015-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8522631
• 关键词: Address; Adolescent; Adult; Advisory Committees; Affect; Age; Anal Intraepithelial Neoplasia; Anal canal; Anogenital venereal warts; Anus; Attention; Attitude; Behavior; Behavioral Research; Belief; Biological; Bisexual; Centers for Disease Control and Prevention (U.S.); Characteristics; Child; Communities; Decision Making; Disease; Educational Intervention; Empirical Research; Ensure; Etiology; Female; Gardasil; Gays; Goals; HIV; HIV Seropositivity; Health Educators; Health education; Heterosexuals; Human Papilloma Virus Vaccine; Human Papillomavirus; Human papilloma virus infection; Human papillomavirus 16; Immunization; Incidence; Infection; Infection prevention; Intervention; Interview; Investigation; Knowledge; Language; Lead; Lesbian; Link; Malignant Neoplasms; Malignant neoplasm of anus; Malignant neoplasm of cervix uteri; Measures; Mentorship; Methods; Modeling; Oncogenic; Outcome; Outcomes Research; Perception; Phase; Population; Population Study; Prevalence Study; Prevention; Public Health; Qualitative Methods; Research; Risk; Sexually Transmitted Diseases; Source; Squamous intraepithelial lesion; Structure; Subgroup; Surveys; Time; Training; Trust; United States Food and Drug Administration; Vaccination; Vaccines; Woman; aged; base; behavior prediction; cancer epidemiology; disorder prevention; health disparity; high risk; innovation; male; men; men who have sex with men; prevent; programs; prophylactic; public health relevance; racial and ethnic; screening; sex; skills; social; theories; transgender; uptake; young man

DESCRIPTION (provided by applicant): Men who have sex with men (MSM) are at increased risk of anal cancer as a result of prevalent anal human papillomavirus (HPV) infection in this population. Prophylactic vaccination is a potentially effective public health strategy for preventing anal cancer. A quadrivalent vaccine is currently approved for the prevention of anal cancer and anal squamous intraepithelial lesions in both males and females. As a result, routine vaccination is recommended for all MSM up through at 26. Maximizing vaccine uptake among populations of MSM will require public health interventions to address factors influencing vaccine acceptability, intentions, and subsequent behavior. Currently, public health educators have limited information available to effectively tailor health education messages and interventions aimed at increasing HPV vaccine uptake among vaccine-eligible adult MSM. The Integrative Model of Behavioral Prediction (IM) is a viable theoretical framework from which to understand HPV vaccine decision-making and to guide social and culturally tailored interventions. According to this model, health education interventions must address the salient HPV-related beliefs and perceptions expressed by young MSM in order to effectively promote vaccination. The long-term goal of this research is to decrease the incidence of anal cancer among MSM by preventing infection of HPV types -16 and -18 through vaccination. The purpose of the proposed research is to understand the factors important to young MSM when making decisions about HPV vaccination by addressing the following specific aims: (1a) Describe salient outcome, normative, and control beliefs related to HPV vaccination among young MSM; (1b) determine factors that underlie these beliefs through semi-structured qualitative interviews and a structured open-ended qualitative survey; (2) explore the influence of socio-demographic characteristics, such as age and racial/ethnic background, in HPV vaccine decision-making among young MSM; and (3) identify information needs and trusted sources of information regarding HPV vaccination among young MSM. These objectives will be addressed in a multi-method sequential qualitative study including semi-structured interviews (Phase 1) and an open-ended qualitative survey (Phase 2) of MSM 18 to 26 years old. The proposed research will reinforce the applicants training plan in cancer epidemiology, the public health needs of lesbian, gay, bisexual and transgender populations, and the use of qualitative methods in health education research. Through a combination of coursework, directed study, and mentorship from his sponsorship team, the proposed training plan will ensure that the applicant will obtain the level of knowledge and skills necessary to build a program of research that will address the critical public health needs of LGBT populations.

描述（由申请人提供）：男性同性恋（MSM）人群中由于肛门人乳头瘤病毒（HPV）感染的流行，肛门癌的风险增加。预防性疫苗接种是预防肛门癌的一种潜在有效的公共卫生策略。四价疫苗目前被批准用于预防男性和女性的肛门癌和肛门鳞状上皮内病变。因此，建议所有MSM在26岁之前进行常规疫苗接种。在MSM人群中最大限度地提高疫苗接种率将需要公共卫生干预措施来解决影响疫苗可接受性、意图和随后行为的因素。目前，公共卫生教育工作者可获得的信息有限，无法有效地定制健康教育信息和干预措施，旨在增加符合疫苗接种条件的成年男男性行为者的HPV疫苗接种率。行为预测的综合模型（IM）是一个可行的理论框架，可以用来理解HPV疫苗的决策，并指导社会和文化定制的干预措施。根据这一模式，健康教育干预措施必须解决突出的HPV相关的信念和看法表达的年轻男男性接触者，以有效地促进疫苗接种。本研究的长期目标是通过接种疫苗预防HPV-16和-18型感染，降低MSM人群肛门癌的发病率。本研究的目的是了解年轻男男性接触者在决定接种HPV疫苗时的重要因素，具体目标如下：（1a）描述年轻男男性接触者对HPV疫苗接种的显著结果、规范性和控制性信念;（1b）通过半结构化定性访谈和结构化开放式定性调查确定这些信念的基础因素;（2）探讨社会人口学特征，如年龄和种族/民族背景，在年轻男男性接触者中HPV疫苗决策的影响;（3）确定年轻男男性接触者对HPV疫苗接种的信息需求和可信的信息来源。这些目标将在一项多方法连续定性研究中得到解决，包括半结构化访谈（第1阶段）和18至26岁男男性接触者的开放式定性调查（第2阶段）。拟议的研究将加强申请人在癌症流行病学方面的培训计划，女同性恋、男同性恋、双性恋和变性者的公共卫生需求，以及在健康教育研究中使用定性方法。通过课程，指导学习和他的赞助团队的指导相结合，拟议的培训计划将确保申请人将获得必要的知识和技能水平，以建立一个研究计划，以解决LGBT人群的关键公共卫生需求。