Development and user testing of a culturally targeted anal cancer prevention decision tool

针对文化的肛门癌预防决策工具的开发和用户测试

基本信息

  • 批准号:
    10664409
  • 负责人:
  • 金额:
    $ 23.78万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2023
  • 资助国家:
    美国
  • 起止时间:
    2023-05-16 至 2024-12-31
  • 项目状态:
    已结题

项目摘要

Project Summary Men who have sex with men (MSM) and transgender women (TGW) are at increased risk of anal cancer because of prevalent anal human papillomavirus (HPV) infections. Anal cancer incidence among MSM ranges from 37 to 131 cases per 100,000. That is roughly 20 to 80 times higher than anal cancer rates in the general population. TGW have similar if not greater risk of precancerous anal lesions than MSM. HPV vaccination provides a unique opportunity to decrease anal cancer disparities for MSM and TGW; however, current HPV vaccine coverage is inadequate. Targeted efforts are urgently needed to increase HPV vaccine uptake among eligible adult MSM and TGW. We propose that leveraging existing HIV prevention services already utilized by MSM and TGW (e.g., pre-exposure prophylaxis [PrEP]) can help to increase the reach and equity of HPV vaccination. MSM/TGW on PrEP have increased need for HPV vaccination given high rates of anal cancer risk factors. However, HPV vaccination is not part of current screening guidelines for PrEP initiation. The long-term objective of this research is to develop a multilevel PrEP clinic-based toolkit to support shared clinical decision making for anal cancer prevention. The objective of this application is to develop patient-level anal cancer prevention content targeted to ethnoracially diverse MSM/TGW PrEP patients. This is a mixed methods health communication approach that engages PrEP patients and providers. We will use perceptual mapping and vector message modeling to create culturally responsive anal cancer prevention messaging focused on HPV vaccination. The methods are informed by the information-motivation-behavioral skills model, guided by an intersectionality framework, and applies best practices in health communication. There are three specific aims: (1) Determine anal cancer prevention information needs and messaging strategies for MSM/TGW on PrEP; (2) Develop targeted anal cancer prevention messages for MSM/TGW on PrEP; and (3) Assess the acceptability, relevance, and comprehensibility of anal cancer prevention messages and identify implementation strategies. In-depth qualitative interviews and focus groups with MSM/TGW on PrEP and PrEP providers will provide qualitative evidence (aims 1 and 3). Perceptual mapping surveys and vector message modeling (aim 2) will be used to develop content for the anal cancer prevention toolkit. This project will help reduce cancer disparities by improving medical decision making and patient-provider communication regarding anal cancer prevention. The multi-level approach addresses gaps as outlined in the National Institute on Minority Health and Health Disparities Research Framework. We focus on behavioral and healthcare system domains at individual and interpersonal levels. The content developed in this study will be included in a multilevel PrEP clinic-based toolkit, providing patient education, provider messaging, and implementation strategies. The effectiveness of the toolkit on HPV vaccine uptake and decisional quality outcomes will be tested in a future R01.
项目总结

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Christopher W. Wheldon其他文献

Loneliness among adult cancer survivors in the United States: prevalence and correlates
美国成年癌症幸存者中的孤独感:患病率及相关因素
  • DOI:
    10.1038/s41598-025-85126-8
  • 发表时间:
    2025-01-31
  • 期刊:
  • 影响因子:
    3.900
  • 作者:
    Christopher W. Wheldon;Yeganeh Shahsavar;Avishek Choudhury;Bryan P. McCormick;Juan R. Albertorio-Díaz
  • 通讯作者:
    Juan R. Albertorio-Díaz
Patient and healthcare provider factors influencing shared clinical decision-making for HPV (human papillomavirus) vaccination among adults aged 27–45 years old in the United States: a systematic review
  • DOI:
    10.1007/s10389-025-02462-9
  • 发表时间:
    2025-04-14
  • 期刊:
  • 影响因子:
    1.600
  • 作者:
    Tanjila Taskin;Idara N. Akpan;Grace Maynard;Sarah A. Alkhatib;Christopher W. Wheldon;Jessica Grace;Erika L. Thompson
  • 通讯作者:
    Erika L. Thompson
Sexual Health Outcomes in Sexual Minority and Heterosexual Men After Prostate Radiation Therapy
前列腺放射治疗后性少数群体男性和异性恋男性的性健康结果
  • DOI:
    10.1016/j.ijrobp.2025.01.023
  • 发表时间:
    2025-06-01
  • 期刊:
  • 影响因子:
    6.500
  • 作者:
    Daniel R. Dickstein;Thodori Kapouranis;Keith Sigel;Christopher W. Wheldon;Eva Nvepu;Noelle Marie Javier;Robert Stewart;Matthew Galsky;John Sfakianos;Joshua D. Safer;Richard Stock;Karyn Goodman;B.R. Simon Rosser;Kathryn E. Flynn;Deborah C. Marshall
  • 通讯作者:
    Deborah C. Marshall
Development and evaluation of a decision aid for HPV vaccination among adults aged 27–45 years old in the United States
  • DOI:
    10.1016/j.compbiomed.2024.109557
  • 发表时间:
    2025-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Christopher W. Wheldon;Jessica Grace;Gregory Zimet;Ellen M. Daley;Idara N. Akpan;Sarah A. Alkhatib;Erika L. Thompson
  • 通讯作者:
    Erika L. Thompson
Sexual and Gender Minority Stress as a Barrier to Cigarette Smoking Cessation
性与性别少数群体压力是戒烟的障碍
  • DOI:
    10.1016/j.amepre.2024.05.004
  • 发表时间:
    2024-09-01
  • 期刊:
  • 影响因子:
    4.500
  • 作者:
    Joshua Zhi Hao Spradau;Christopher W. Wheldon
  • 通讯作者:
    Christopher W. Wheldon

Christopher W. Wheldon的其他文献

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{{ truncateString('Christopher W. Wheldon', 18)}}的其他基金

Beliefs and decision-making about HPV vaccination among young men who have sex wi
有性行为的年轻男性对 HPV 疫苗接种的信念和决策
  • 批准号:
    8653421
  • 财政年份:
    2013
  • 资助金额:
    $ 23.78万
  • 项目类别:
Beliefs and decision-making about HPV vaccination among young men who have sex wi
有性行为的年轻男性对 HPV 疫苗接种的信念和决策
  • 批准号:
    8522631
  • 财政年份:
    2013
  • 资助金额:
    $ 23.78万
  • 项目类别:

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