Beliefs and decision-making about HPV vaccination among young men who have sex wi

有性行为的年轻男性对 HPV 疫苗接种的信念和决策

• 批准号: 8653421
• 负责人: Christopher W. Wheldon
• 金额: $ 3.3万
• 依托单位: UNIVERSITY OF SOUTH FLORIDA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-01 至 2015-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8653421
• 关键词: Address; Adolescent; Adult; Advisory Committees; Affect; Age; Anal Intraepithelial Neoplasia; Anal canal; Anogenital venereal warts; Anus; Attention; Attitude; Behavior; Behavioral Research; Belief; Biological; Centers for Disease Control and Prevention (U.S.); Characteristics; Child; Communities; Decision Making; Disease; Educational Intervention; Empirical Research; Ensure; Etiology; Female; Gardasil; Goals; HIV; HIV Seropositivity; Health Educators; Health education; Heterosexuals; Human Papilloma Virus Vaccination; Human Papilloma Virus Vaccine; Human Papillomavirus; Human papilloma virus infection; Human papillomavirus 16; Immunization; Incidence; Infection; Infection prevention; Intervention; Interview; Investigation; Knowledge; Language; Lead; Lesbian Gay Bisexual Transgender; Link; Malignant Neoplasms; Malignant neoplasm of anus; Malignant neoplasm of cervix uteri; Measures; Mentorship; Methods; Modeling; Oncogenic; Outcome; Outcomes Research; Perception; Phase; Population; Population Study; Prevalence Study; Prevention; Public Health; Qualitative Methods; Research; Risk; Sexually Transmitted Diseases; Source; Squamous intraepithelial lesion; Structure; Subgroup; Surveys; Time; Training; Trust; United States Food and Drug Administration; Vaccination; Vaccines; Woman; aged; base; behavior prediction; cancer epidemiology; disorder prevention; health disparity; high risk; innovation; male; men; men who have sex with men; prevent; programs; prophylactic; public health relevance; racial and ethnic; screening; sex; skills; social; theories; uptake; young man

DESCRIPTION (provided by applicant): Men who have sex with men (MSM) are at increased risk of anal cancer as a result of prevalent anal human papillomavirus (HPV) infection in this population. Prophylactic vaccination is a potentially effective public health strategy for preventing anal cancer. A quadrivalent vaccine is currently approved for the prevention of anal cancer and anal squamous intraepithelial lesions in both males and females. As a result, routine vaccination is recommended for all MSM up through at 26. Maximizing vaccine uptake among populations of MSM will require public health interventions to address factors influencing vaccine acceptability, intentions, and subsequent behavior. Currently, public health educators have limited information available to effectively tailor health education messages and interventions aimed at increasing HPV vaccine uptake among vaccine-eligible adult MSM. The Integrative Model of Behavioral Prediction (IM) is a viable theoretical framework from which to understand HPV vaccine decision-making and to guide social and culturally tailored interventions. According to this model, health education interventions must address the salient HPV-related beliefs and perceptions expressed by young MSM in order to effectively promote vaccination. The long-term goal of this research is to decrease the incidence of anal cancer among MSM by preventing infection of HPV types -16 and -18 through vaccination. The purpose of the proposed research is to understand the factors important to young MSM when making decisions about HPV vaccination by addressing the following specific aims: (1a) Describe salient outcome, normative, and control beliefs related to HPV vaccination among young MSM; (1b) determine factors that underlie these beliefs through semi-structured qualitative interviews and a structured open-ended qualitative survey; (2) explore the influence of socio-demographic characteristics, such as age and racial/ethnic background, in HPV vaccine decision-making among young MSM; and (3) identify information needs and trusted sources of information regarding HPV vaccination among young MSM. These objectives will be addressed in a multi-method sequential qualitative study including semi-structured interviews (Phase 1) and an open-ended qualitative survey (Phase 2) of MSM 18 to 26 years old. The proposed research will reinforce the applicants training plan in cancer epidemiology, the public health needs of lesbian, gay, bisexual and transgender populations, and the use of qualitative methods in health education research. Through a combination of coursework, directed study, and mentorship from his sponsorship team, the proposed training plan will ensure that the applicant will obtain the level of knowledge and skills necessary to build a program of research that will address the critical public health needs of LGBT populations.

描述（由申请人提供）：由于肛门人类乳头瘤病毒（HPV）感染在该人群中流行，与男性发生性行为的男性（MSM）患肛门癌的风险增加。预防性疫苗接种是预防肛门癌的潜在有效的公共卫生策略。一种四价疫苗目前被批准用于预防男性和女性肛门癌和肛门鳞状上皮内病变。因此，建议所有男男性接触者在26岁之前进行常规疫苗接种。最大限度地提高MSM人群的疫苗接种率将需要公共卫生干预措施，以解决影响疫苗可接受性、意图和随后行为的因素。目前，公共卫生教育工作者可获得的信息有限，无法有效地定制健康教育信息和干预措施，旨在提高符合疫苗条件的成年男男性行为者的HPV疫苗接种率。行为预测的综合模型（IM）是一个可行的理论框架，从中了解HPV疫苗决策和指导社会和文化量身定制的干预措施。根据该模型，健康教育干预措施必须解决年轻男男性行为者所表达的与hpv相关的突出信念和观念，以便有效地促进疫苗接种。这项研究的长期目标是通过接种疫苗预防HPV -16和-18型感染，从而降低MSM中肛门癌的发病率。拟议研究的目的是通过解决以下具体目标，了解年轻男男性行为者在做出HPV疫苗接种决定时的重要因素：（1a）描述与年轻男男性行为者中HPV疫苗接种相关的显着结果，规范和控制信念；（1b）通过半结构化定性访谈和结构化开放式定性调查确定这些信念背后的因素；(2)探讨年龄、种族/民族背景等社会人口学特征对年轻男男性行为者HPV疫苗接种决策的影响；(3)确定年轻男男性行为者关于HPV疫苗接种的信息需求和可信信息来源。这些目标将在一项多方法连续定性研究中得到解决，包括半结构化访谈（第一阶段）和对18至26岁的男男性行为者的开放式定性调查（第二阶段）。建议的研究将加强申请人在癌症流行病学、女同性恋、男同性恋、双性恋和变性人群的公共卫生需求以及在健康教育研究中使用定性方法方面的培训计划。通过课程学习、定向学习和赞助团队的指导相结合，拟议的培训计划将确保申请人获得必要的知识和技能水平，以建立一个研究项目，解决LGBT人群的关键公共卫生需求。

项目成果

An Assessment of Cancer Education Needs to Promote Mid-Adult HPV Vaccination Among Male Sexual Minorities.

癌症教育评估需要促进男性性少数人群中成人 HPV 疫苗接种。

• DOI: 10.1007/s13187-019-01644-w
• 发表时间: 2021
• 期刊: Journal of cancer education : the official journal of the American Association for Cancer Education
• 作者: Wheldon,ChristopherW;Maness,SarahB
• 通讯作者: Maness,SarahB