Integrated Biological Systems Training in Oncology

肿瘤学综合生物系统培训

• 批准号: 8697020
• 负责人: STEPHEN R. HANN
• 金额: $ 40.08万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-06-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8697020
• 关键词: Training; biological systems; oncology

DESCRIPTION (provided by applicant): The objective of this first renewal of the Integrated Biological Systems Training in Oncology (IBSTO) program is to continue to prepare predoctoral students and postdoctoral fellows for careers in cancer research with comprehensive training in basic and translational research. IBSTO training focuses on basic cellular processes and mechanisms that are shared between cell biology and developmental biology that are critical to understanding how cells become tumorigenic and on how to translate this basic research knowledge to the diagnosis, treatment and prevention of cancer. The IBSTO program takes place in an active and growing Medical Center environment with state-of-the-art facilities, a vibrant NCI-designated comprehensive cancer center, top-ranked basic science departments, an Interdisciplinary Graduate Program in Biomedical Sciences, and an active Office of Postdoctoral Affairs. The Program Director has a strong record of basic cancer research and administrative experience. In our first four years we have already recruited 22 outstanding predoctoral and postdoctoral trainees that have been very productive. Trainees have been placed with experienced, well-funded, productive preceptors in an interactive research environment with extensive resources. The three broad areas of experience of our preceptors are in cell biology, developmental biology/genetics and medicine. Each trainee has mentors from each group to provide unique and valuable perspectives to enhance their cancer-related research training. The goals of our training program are to provide proactive mentoring and oversight, provide cross-discipline education and research, provide training in cutting edge methodology, develop useful academic skills, foster interactions with faculty and other trainees, provide exposure to current cancer research discoveries, and provide exposure to clinical cancer treatment and translational research. In this renewal we have strengthened our clinical/translational component with the addition of an Associate Director and new preceptors who focus on translational research and new required clinical training experience in oncology. We strongly believe that integrating basic science research training in cell biology, developmental biology and genetics with translational and clinical experience allows a better understanding of the multiple lesions in cellular processes that define cancer, which is critical t diagnosing, treating and eventually preventing of this disease.

描述（由申请人提供）：肿瘤学综合生物系统培训 (IBSTO) 项目首次更新的目标是通过基础和转化研究方面的全面培训，继续为博士生和博士后研究员从事癌症研究职业做好准备。 IBSTO 培训重点关注细胞生物学和发育生物学之间共享的基本细胞过程和机制，这对于了解细胞如何致瘤以及如何将这些基础研究知识转化为癌症的诊断、治疗和预防至关重要。 IBSTO 项目在一个活跃且不断发展的医疗中心环境中进行，该医疗中心拥有最先进的设施、充满活力的 NCI 指定综合癌症中心、一流的基础科学系、生物医学科学研究跨学科研究生项目以及活跃的博士后事务办公室。项目主任拥有丰富的基础癌症研究记录和管理经验。在我们成立的前四年里，我们已经招募了 22 名优秀的博士前和博士后培训生，他们的成果非常丰富。学员被安置在一个拥有丰富资源的互动研究环境中，与经验丰富、资金充足、富有成效的导师一起工作。我们的导师的三个广泛的经验领域是细胞生物学、发育生物学/遗传学和医学。每个学员都有来自每个小组的导师，为他们提供独特且有价值的观点，以加强他们与癌症相关的研究培训。我们培训计划的目标是提供积极的指导和监督，提供跨学科教育和研究，提供前沿方法的培训，培养有用的学术技能，促进与教师和其他学员的互动，提供当前癌症研究发现的机会，并提供临床癌症治疗和转化研究的机会。在这次更新中，我们加强了我们的临床/转化部分，增加了一名副主任和新的导师，他们专注于转化研究和肿瘤学方面新的所需临床培训经验。我们坚信，将细胞生物学、发育生物学和遗传学方面的基础科学研究训练与转化和临床经验相结合，可以更好地理解定义癌症的细胞过程中的多种病变，这对于诊断、治疗和最终预防这种疾病至关重要。