Integrated Biological Systems Training in Oncology

描述（由申请人提供）：肿瘤学综合生物系统培训 (IBSTO) 计划的目标是通过基础和转化研究的全面培训，为博士前学生和博士后研究员从事癌症研究职业做好准备。该培训重点关注细胞生物学和发育生物学之间共享的基本细胞过程和机制，这些过程和机制对于了解细胞如何致瘤以及如何将这些基础研究知识转化为癌症的诊断、治疗和预防至关重要。 IBSTO 项目将在一个活跃且不断发展的医疗中心环境中进行，该医疗中心拥有最先进的设施、一个充满活力的 NCI 指定综合癌症中心、顶级基础科学系、生物医学跨学科研究生项目、活跃的博士后事务办公室以及与邻近的少数族裔服务医学院的联盟。项目主任拥有丰富的基础癌症研究记录和管理经验。学员将与经验丰富、资金充足、富有成效的导师一起生活在一个资源丰富的互动研究环境中。我们的导师的三个广泛的经验领域是细胞生物学、发育生物学/遗传学和医学。每个学员都会有来自每个小组的导师，为他们提供独特且有价值的观点，以加强他们与癌症相关的研究培训。我们培训计划的目标是提供积极的指导和监督，提供跨学科教育和研究，提供前沿方法的培训，培养有用的学术技能，促进与教师和其他学员的互动，提供当前癌症研究发现的机会，并提供临床癌症治疗和转化研究的机会。我们坚信，必须整合细胞生物学、发育生物学和遗传学方面的基础科学研究培训，以便了解定义癌症的细胞过程中的多种病变，同时了解和了解癌症的临床方面。这种综合理解对于我们的诊断、治疗以及最终预防这种疾病至关重要。

DESCRIPTION (provided by applicant): The objective of the Integrated Biological Systems Training in Oncology (IBSTO) program is to prepare predoctoral students and postdoctoral fellows for careers in cancer research with comprehensive training in basic and translational research. This training focuses on basic cellular processes and mechanisms that are shared between cell biology and developmental biology that are critical to understanding how cells become tumorigenic and on how to translate this basic research knowledge to the diagnosis, treatment and prevention of cancer. The IBSTO program will take place in an active and growing Medical Center environment with state-of-the-art facilities, a vibrant NCI-designated comprehensive cancer center, top ranked basic science departments, an Interdisciplinary Graduate Program in Biomedical Sciences, an active Office of Postdoctoral Affairs, and an Alliance with a neighboring minority-serving medical college. The Program Director has a strong record of basic cancer research and administrative experience. Trainees will be placed with experienced, well-funded, productive preceptors in an interactive research environment with extensive resources. The three broad areas of experience of our preceptors are in cell biology, developmental biology/genetics and medicine. Each trainee will have mentors from each group to provide unique and valuable perspectives to enhance their cancer-related research training. The goals of our training program are to provide proactive mentoring and oversight, provide cross-discipline education and research, provide training in cutting edge methodology, develop useful academic skills, foster interactions with faculty and other trainees, provide exposure to current cancer research discoveries, and provide exposure to clinical cancer treatment and translational research. We strongly believe that it is essential to integrate basic science research training in cell biology, developmental biology and genetics that allows understanding of the multiple lesions in cellular processes that define cancer, with a knowledge and appreciation of the clinical aspects of cancer. This combined understanding will be critical to our diagnosis, treatment and eventually the prevention of this disease.