Integrated Biological Systems Training in Oncology

项目摘要 肿瘤学综合生物系统培训（IBSTO）的第二次更新的目标 该计划是继续准备博士前学生和博士后研究员的职业生涯在癌症 在基础研究和转化研究的全面培训。IBSTO培训侧重于基础 细胞生物学和发育生物学之间共享的细胞过程和机制， 对于理解细胞如何成为致瘤细胞以及如何将这一基础研究转化为 癌症的诊断、治疗和预防知识。IBSTO计划发生在一个 活跃和成长的环境，拥有最先进的设施，一个充满活力的NCI指定的综合 癌症中心，一流的基础科学部门，生物医学跨学科研究生课程 科学，和一个活跃的博士后事务办公室。在最初的九年里，我们招募了42名 优秀的博士前和博士后培训生，他们非常富有成效。受训人员已 与经验丰富，资金充足，富有成效的导师在一个互动的研究环境， 广泛的资源。我们导师的三个广泛的经验领域是细胞生物学， 发育生物学/遗传学和医学。我们的培训计划的目标是提供积极主动的 指导和监督，提供跨学科的教育和研究，提供尖端的培训， 方法，发展有用的学术技能，促进与教师和其他学员的互动，提供 接触目前的癌症研究发现，并提供接触临床癌症治疗， 翻译研究在这次更新中，我们通过增加一个新的IBSTO来加强我们的培训活动 Day Retreat，一个新的跨学科合作研讨会，并支持我们的临床/翻译队列 的preceptors。我们还增加了一个新的外部咨询委员会，以提供持续的反馈， 方案的评价。我们有一位新的项目主任，他在基础癌症方面有很好的记录， 研究和行政经验。我们认为，将基础科学研究培训融入细胞 生物学，发育生物学和遗传学的转化和临床经验，可以更好地 了解定义癌症的细胞过程中的多种病变，这对诊断至关重要， 治疗并最终预防这种疾病。

PROJECT SUMMARY The objective of this second renewal of the Integrated Biological Systems Training in Oncology (IBSTO) program is to continue to prepare predoctoral students and postdoctoral fellows for careers in cancer research with comprehensive training in basic and translational research. IBSTO training focuses on basic cellular processes and mechanisms that are shared between cell biology and developmental biology that are critical to understanding how cells become tumorigenic and on how to translate this basic research knowledge to the diagnosis, treatment and prevention of cancer. The IBSTO program takes place in an active and growing environment with state-of–the-art facilities, a vibrant NCI-designated comprehensive cancer center, top-ranked basic science departments, an Interdisciplinary Graduate Program in Biomedical Sciences, and an active Office of Postdoctoral Affairs. In our first nine years, we have recruited 42 outstanding predoctoral and postdoctoral trainees that have been very productive. Trainees have been placed with experienced, well-funded, productive preceptors in an interactive research environment with extensive resources. The three broad areas of experience of our preceptors are in cell biology, developmental biology/genetics and medicine. The goals of our training program are to provide proactive mentoring and oversight, provide cross-discipline education and research, provide training in cutting edge methodology, develop useful academic skills, foster interactions with faculty and other trainees, provide exposure to current cancer research discoveries, and provide exposure to clinical cancer treatment and translational research. In this renewal, we have strengthened our training activities by adding a new IBSTO Day Retreat, a new cross-disciplinary collaboration workshop, and bolstering our clinical/translational cohort of preceptors. We have also added a new External Advisory Board to provide ongoing feedback and evaluation of the program. And we have a new Program Director who has a strong record of basic cancer research and administrative experience. We believe that integrating basic science research training in cell biology, developmental biology and genetics with translational and clinical experience allows a better understanding of the multiple lesions in cellular processes that define cancer, which is critical to diagnosing, treating and eventually preventing of this disease.