Western New York Cancer Coalition (WNYC2) Center to Reduce Disparities

描述（由申请人提供）：西纽约（WNY）社区在烟草使用和戒烟实践、参与研究机会和肺癌、乳腺癌、前列腺癌和结直肠癌的发病率方面存在显著差异。拟议中的西纽约癌症联盟（WNYC）中心将通过将我们的工作重点放在布法罗和尼亚加拉瀑布等城市的少数民族和城市社区以及邻近肖托夸县的阿巴拉契亚农村社区的临床实践上，解决我们地区最显著的这些差异和癌症负担。我们从社会生态模式出发，通过临床和社区伙伴关系来减少差异，努力增强社会资本并减少感知的种族主义。该中心的目标是确保所有居民受益于现有的临床和科学进步，以减少烟草使用，促进健康的生活方式和行为，早期发现癌症，并参与临床和研究项目，以消除癌症不平等。具体目标是：目标1。通过提供资源、培训、外展和干预措施来改善临床环境，以提高临床实践的质量。目标2。通过向社区组织和合作伙伴提供技术援助和量身定制的外联干预措施，加强对社区的外联，以增加对有益的生物医学和行为程序的了解、获取和使用。目标3。加强CBPR培训，提供培训、指导、CBPR和跨学科研究经验和资源，培养初级研究员和博士后。目标4。通过与社区合作伙伴调查变量和方法，开展严格的CBPR研究，以减少癌症差异。我们建议与社区PCP实践和患者合作进行全面的ROI，以研究实践增强在非洲裔美国人和农村患者中增加戒烟的比较有效性；以及与布法罗拉丁裔社区进行的一项试点研究，研究招募癌症中心生物标本库项目参与者的机制。WNYC中心还包括在行政核心、多维拓展计划和新颖培训计划方面经验丰富的领导。

DESCRIPTION (provided by applicant): Western New York (WNY) communities suffer from significant disparities in tobacco use and cessation practices, participation in research opportunities and rates of lung, breast, prostate and colorectal cancers. The proposed Western New York Cancer Coalition (WNYC) Center will address the most striking of these disparities and the burden of cancer in our region by focusing our efforts on minority and urban communities and clinical practices in the cities of Buffalo and Niagara Falls and rural Appalachian communities in neighboring Chautauqua County. We approach the reduction of disparities with clinical and community partnerships from a socio ecological model, with efforts to enhance social capital and reduce perceived racism. The goal of the Center is to ensure that all residents benefit from available clinical and scientific advances to reduce tobacco use, promote healthy lifestyles and behaviors, detect cancer early and participate in clinical and research programs in order to eliminate cancer inequities. The Specific Aims are: Aim 1. Enhance clinical environments by providing resources, training, outreach and interventions to improve the quality of clinical practice. Aim 2. Enhance outreach to the community by providing technical assistance and tailored outreach interventions to community organizations and partners to increase knowledge of, access to, and use of, beneficial biomedical and behavioral procedures. Aim 3. Enhance CBPR training by provide training, mentoring, CBPR and trans-disciplinary research experiences and resources to prepare junior investigators and post-doctoral fellows. Aim 4. Conduct rigorous CBPR research by investigating variables and methods with our community partners to reduce cancer disparities. We propose a full ROI in collaboration with community PCP practices and patients to study the comparative effectiveness of practice enhancements to increase smoking cessation in African American and rural patients; and a pilot study with the Buffalo Latino community to study mechanisms to recruit participants to the cancer center biospecimen banking program. The WNYC^ Center also includes experienced leadership in an Administrative Core, multidimensional Outreach Program, and novel Training Program.