Intervention for Persons with Co-Occurring Disorders Leaving Residential Tx

项目总结 这份修订后的K01职业发展申请表旨在为詹妮弗·I·曼纽尔博士 作为一名独立调查员从事富有成效的职业生涯，在 发展/适应和实施改善个人生活的干预措施 正在发生的药物使用和精神健康障碍。在戴斯·斯维基斯博士的主要指导下， 曼纽尔将接受正式指导和直接监督，并完成正式(即课程作业)和 非正式的(如研讨会、培训、会议)教学培训，以增加她的知识和技能 以下领域：(1)调整和实施循证干预措施；(2)参与性规划 方法；(3)定量和定性的方法和分析；(4)赠款的撰写和管理；(5) 负责任的研究行为。拟议的研究使用了多阶段方法，从战略上 与申请人的培训计划相吻合。具体地说，申请人使用参与式规划方法来适应 并实施既定的、国家认可的干预措施，关键时间干预措施，以实现新的 同时患有药物使用和精神健康障碍的人群和环境 在住宅药物滥用治疗后容易复发。具体目标是：(1)确定 社区共生疾病患者重返社区面临的挑战与对策 药物滥用治疗及其专业人员(例如，提供者)和非专业人员(例如，家人，朋友， 社区成员)支持；(2)调整和翻译CTI，使其适用于在 利用参与式规划，从住宅药物滥用治疗过渡到社区 方法；及(3)进行一项初步研究，以检视 与通常的出院计划服务相比，采用了CTI。拟议的研究有助于 候选人的职业发展，因为这增加了她现有的研究协调和 二次分析，通过从头开始的研究和进行初级数据分析，以及 产生后续R01的试点数据，以测试调整后的CTI干预在较大 比例。指导这一申请的参与性规划框架如果成功，可以用来准备 对其他弱势人群的干预措施，并通过制定系统的 帮助缩小研究与实践之间差距的方法。

PROJECT SUMMARY This revised K01 career development application is designed to prepare Jennifer I. Manuel, Ph.D., for a productive career as an independent investigator who conducts research and advances knowledge in the development/adaptation and implementation of interventions that improve the lives of individuals with co- occurring substance use and mental health disorders. Under the primary mentorship of Dr. Dace Svikis, Dr. Manuel will receive formal mentoring and direct supervision, and complete formal (i.e., coursework) and informal (e.g., seminars, trainings, conferences) didactic training to increase her knowledge and skills in the following areas: (1) adaptation and implementation of evidence-based interventions; (2) participatory planning methods; (3) quantitative and qualitative methods and analyses; (4) grant writing and management; and (5) responsible conduct of research. The proposed research uses a multi-phase approach that strategically dovetails the applicant's training plan. Specifically, the applicant uses participatory planning methods to adapt and implement an established, nationally-recognized intervention, Critical Time Intervention, for a new population and setting among individuals with co-occurring substance use and mental health disorders who are vulnerable to relapse following residential substance abuse treatment. The specific aims are to: (1) identify challenges and strategies of community reentry among individuals with co-occurring disorders in residential substance abuse treatment and their professional (e.g., providers) and nonprofessional (e.g., family, friends, community members) supports; (2) adapt and translate CTI for individuals with co-occurring disorders during the transition from residential substance abuse treatment into the community, utilizing participatory planning methods; and (3) conduct a pilot study to examine the feasibility, acceptability, and preliminary outcomes of the adapted CTI compared to usual discharge planning services. The proposed research contributes to the candidate's career development, as it augments her existing experience in research coordination and secondary analysis through leading a study from the ground up and conducting primary data analysis, and yields pilot data for a subsequent R01 to test the effectiveness of the adapted CTI intervention on a larger scale. The participatory planning framework that guides this application, if successful, could be used to prepare interventions for other vulnerable populations and advance implementation science by developing a systematic approach for helping to close the gap between research and practice.