Intervention for Persons with Co-Occurring Disorders Leaving Residential Tx

描述(由申请人提供)：这份修订后的K01职业发展申请旨在为詹妮弗·I·曼纽尔博士作为一名独立调查员的富有成效的职业生涯做准备，她进行研究，并提高在开发/适应和实施干预措施方面的知识，以改善患有药物使用和精神健康障碍的个人的生活。在Dace Svikis博士的主要指导下，Manuel博士将接受正式指导和直接监督，并完成正式(即课程作业)和非正式(如研讨会、培训、会议)教学培训，以增加她在以下领域的知识和技能：(1)循证干预措施的适应和实施；(2)参与式规划方法；(3)定量和定性方法和分析；(4)赠款撰写和管理；以及(5)负责任的研究行为。拟议的研究采用了多阶段的方法，在战略上与申请者的培训计划相吻合。具体地说，申请人使用参与性规划方法来调整和实施既定的、国家认可的干预措施、关键时间干预措施，适用于新的人口和在住宅药物滥用治疗后容易复发的同时患有药物使用和精神健康障碍的个人。具体目标是：(1)确定在住宅药物滥用治疗中的共生障碍患者及其专业人员(例如提供者)和非专业人员(例如家人、朋友、社区成员)的支持下重新进入社区的挑战和策略；(2)利用参与性规划方法，为从住宅药物滥用治疗过渡到社区的共生疾病患者改编和翻译CTI；以及(3)进行一项试点研究，以检验调整后的CTI与通常的出院规划服务相比的可行性、可接受性和初步结果。拟议的研究有助于候选人的职业发展，因为它通过从头开始领导一项研究并进行初级数据分析，增强了她在研究协调和二次分析方面的现有经验，并为随后的R01产生试点数据，以在更大范围内测试适应的CTI干预的有效性。指导这一应用的参与性规划框架如果成功，可以用来为其他弱势群体准备干预措施，并通过制定一种系统的方法帮助缩小研究与实践之间的差距来推进实施科学。

DESCRIPTION (provided by applicant): This revised K01 career development application is designed to prepare Jennifer I. Manuel, Ph.D., for a productive career as an independent investigator who conducts research and advances knowledge in the development/adaptation and implementation of interventions that improve the lives of individuals with co- occurring substance use and mental health disorders. Under the primary mentorship of Dr. Dace Svikis, Dr. Manuel will receive formal mentoring and direct supervision, and complete formal (i.e., coursework) and informal (e.g., seminars, trainings, conferences) didactic training to increase her knowledge and skills in the following areas: (1) adaptation and implementation of evidence-based interventions; (2) participatory planning methods; (3) quantitative and qualitative methods and analyses; (4) grant writing and management; and (5) responsible conduct of research. The proposed research uses a multi-phase approach that strategically dovetails the applicant's training plan. Specifically, the applicant uses participatory planning methods to adapt and implement an established, nationally-recognized intervention, Critical Time Intervention, for a new population and setting among individuals with co-occurring substance use and mental health disorders who are vulnerable to relapse following residential substance abuse treatment. The specific aims are to: (1) identify challenges and strategies of community reentry among individuals with co-occurring disorders in residential substance abuse treatment and their professional (e.g., providers) and nonprofessional (e.g., family, friends, community members) supports; (2) adapt and translate CTI for individuals with co-occurring disorders during the transition from residential substance abuse treatment into the community, utilizing participatory planning methods; and (3) conduct a pilot study to examine the feasibility, acceptability, and preliminary outcomes of the adapted CTI compared to usual discharge planning services. The proposed research contributes to the candidate's career development, as it augments her existing experience in research coordination and secondary analysis through leading a study from the ground up and conducting primary data analysis, and yields pilot data for a subsequent R01 to test the effectiveness of the adapted CTI intervention on a larger scale. The participatory planning framework that guides this application, if successful, could be used to prepare interventions for other vulnerable populations and advance implementation science by developing a systematic approach for helping to close the gap between research and practice.