NANOTOX 2014, 7th International Nanotoxicology Congress

NANOTOX 2014，第七届国际纳米毒理学大会

• 批准号: 8718354
• 负责人: Valerian E Kagan
• 金额: $ 0.8万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-17 至 2015-04-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8718354
• 关键词: Address; Adverse effects; Area; Biological; Biology; Cell physiology; Cells; Characteristics; Chemicals; Chemistry; Communities; Computer Simulation; Congresses; Cosmetics; Data; Dimensions; Discipline; Dose; Drug Kinetics; Ecosystem; Engineering; Environment; Environmental Health; Event; Exposure to; Fostering; Goals; Gray unit of radiation dose; Growth; Health; Human; Immune response; Industry; International; Knowledge; Laboratories; Life; Manufacturer Name; Meleagris gallopavo; Methodology; Methods; Modeling; Molecular; Molecular Machines; Molecular Mechanisms of Action; Nanotechnology; Occupational; Paper; Participant; Production; PubMed; Public Health; Publications; Publishing; Regulation; Research; Research Personnel; Risk; Risk Assessment; Safety; Scientist; Semiconductors; Series; Societies; Surface; Systems Biology; Technology; Tissues; Toxic effect; Toxicology; Work; base; design; experience; innovation; lectures; man; meetings; nano; nanomaterials; nanomedicine; nanoparticle; nanotoxicology; programs; public health relevance; response; scientific organization; symposium

DESCRIPTION (provided by applicant): Recent advances in nanotechnology have revolutionized all aspects of life, from engineering, semiconductors, building materials to cosmetics and nanomedicine. The unique physico-chemical characteristics combined with the vast surface area make the biological effects of nano-materials and their interactions with cells, tissues and biofluids largely unpredictable. The increasing use of engineered nanomaterials raises concerns about inadvertent exposure to these materials and the potential for adverse effects on human health and the environment. As a result of this, a new and explosively developing field of toxicology - nanotoxicology - has emerged. Experimental work in the field of nanotoxicology is progressing at exponential rate. In spite of this, there is still a fundamental lack of data on the potential impacts of nanomaterials n human health, and the environment, including natural ecosystems. Filling this gap of knowledge will require an unprecedented degree of national and international coordination between scientific organizations, regulatory agencies, and stakeholders. The proposed International Conference Nanotoxicology-2014 is an important step in this direction. The International Conference Nanotoxicology-2014 - to be held in Antalya, Turkey from April 23 through 26, 2014 - will bring together current research leaders in the field of toxicology of nanomaterial's from material scientists, chemists and manufacturers to molecular toxicologists, risk assessment experts as well as clinicians and translational scientists involved in biomedical applications of nanoparticles. Since 2006, when the first International conference on nanotoxicology has been initiated and organized in the US (Miami), a series of bi-annual meetings was conducted in Zurich (2008), Edinburgh (2010), and Beijing (2012). These conferences represented the major scientific events in the field of Nano toxicology whereby most innovative and significant breakthrough results in the emerging discipline were strategically disseminated and made available for the research community of scientists, representatives of nanomaterial's manufacturing industries, public health officials and experts in risk assessment/regulatory issues. The primary goal of the conference is to create the opportunity for cross disciplinary discussions for investigators with different fields of expertise working together to understand the chemistry, biology, molecular mechanisms of action and toxicity of nanomaterial's, hence to provide basis for risk assessments thus facilitating the design and production of nanomaterial's with minimized adverse effects on human health and the environment. The topics of the conference are focused on the latest most innovative areas of the exploding discipline of nanotoxicology: nanotoxicology and human toxicology, nano-environmental health and safety, eco-nanotoxicology, dose-response paradigm, molecular mechanisms of nontoxicity, immune responses to nanoparticles, nanomedicine, pharmacokinetics and particokinetics, nano-bio interface and nanobiomaterials, exposure scenarios and risk assessment of nanomaterials, systems biology approaches to nanosafety, In Silico modeling approaches including nano-QSARs, regulatory challenges of nanotechnology risks. A series of lectures on "Methods in nanosafety research" for young investigators will also be included in the program of the conference. Two special round-table discussions will be focused on the world-wide strategic research agenda in the field of nanosafety. Overall, the topics of the conference will address the major directions of research relevant to concerns associated with the environmental, occupational and biomedical exposures to nanomaterials. The conference will create opportunities for participants to present and share experiences, explore new directions and debate topics with experts from across the globe in the field of nanotoxicology.

描述（由申请人提供）： 纳米技术的最新进展已经彻底改变了生活的各个方面，从工程，半导体，建筑材料到化妆品和纳米医学。独特的物理化学特性与巨大的表面积相结合，使纳米材料的生物效应及其与细胞、组织和生物流体的相互作用在很大程度上不可预测。越来越多地使用工程纳米材料引起了人们对无意中接触这些材料以及可能对人类健康和环境产生不利影响的担忧。因此，出现了一个新的和爆炸性发展的毒理学领域-纳米毒理学。纳米毒理学领域的实验工作正在以指数速度发展。尽管如此，关于纳米材料对人类健康和环境（包括自然生态系统）的潜在影响的数据仍然基本缺乏。填补这一知识空白需要科学组织、监管机构和利益相关者之间进行前所未有的国家和国际协调。拟议的2014年国际纳米毒理学会议是朝着这一方向迈出的重要一步。国际会议纳米毒理学-2014年-将在安塔利亚，土耳其举行从4月23日至26日，2014年-将汇集当前的研究领导者在毒理学领域的纳米材料的从材料科学家，化学家和制造商的分子毒理学家，风险评估专家以及临床医生和翻译科学家参与纳米粒子的生物医学应用。自2006年首次在美国（迈阿密）发起和组织纳米毒理学国际会议以来，在苏黎世（2008年）、爱丁堡（2010年）和北京（2012年）举行了一系列半年一次的会议。这些会议代表了纳米毒理学领域的重大科学活动，其中新兴学科中最具创新性和重大突破性的成果得到了战略性的传播，并提供给科学家研究界、纳米材料制造业代表、公共卫生官员和风险评估/监管问题专家。会议的主要目标是为具有不同专业知识领域的研究人员创造跨学科讨论的机会，共同了解 纳米材料的化学、生物学、分子作用机制和毒性，从而为风险评估提供依据，从而促进纳米材料的设计和生产，最大限度地减少对人类健康和环境的不利影响。会议的主题集中在纳米毒理学爆炸性学科的最新最创新领域：纳米毒理学和人类毒理学，纳米环境健康和安全，生态纳米毒理学，剂量反应范式，无毒性的分子机制，对纳米颗粒的免疫反应，纳米医学，药代动力学和部分动力学，纳米生物界面和纳米生物材料，纳米材料的暴露情景和风险评估，纳米安全的系统生物学方法，包括纳米QSAR在内的计算机模拟方法，纳米技术风险的监管挑战。为年轻研究人员举办的一系列关于“纳米安全研究方法”的讲座也将列入会议计划。两个特别圆桌讨论会将集中讨论纳米安全领域的全球战略研究议程。总体而言，会议的主题将涉及与纳米材料的环境、职业和生物医学暴露相关的主要研究方向。会议将为与会者提供机会，与来自地球仪纳米毒理学领域的专家一起展示和分享经验，探索新的方向和辩论主题。