CCTN - CONTRACEPTIVE CLINICAL TRIALS - MALE SITES, NES/TES STUDY

CCTN - 避孕临床试验 - 男性部位、NES/TES 研究

• 批准号: 8880524
• 负责人: CHRISTINA WANG
• 金额: $ 33.29万
• 依托单位: LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-02-17 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8880524
• 关键词: Biological Assay; Boxing; Clinical Protocols; Clinical Trials; Contraceptive Agents; Data; Dose; Drug Formulations; Drug Kinetics; Evaluation; Gel; Gonadotropins; Healthcare; Hormonal; Hormones; Instruction; Label; Laboratory Study; National Institute of Child Health and Human Development; Nestorone; Pharmacodynamics; Population; Protocols documentation; Reporting; SHBG gene; Safety; Sampling; Science; Serum; Services; Shipping; Ships; Site; Specimen; Testing; Testosterone; drug development; male; men; particle; response; styrofoam

Evaluate suppression of gonadotrophins in response to Nestorone and Testosterone gel compared to Testosterone gel. CENTRAL LABORATORY FOR THE STUDY ON THE 28 DAYS REPEAT-DOSE SAFETY AND TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS STUDY OF COMBINED NESTORONE/TESTOSTERONE GEL IN HEALTHY MEN The objective of this Task Order is to obtain valid and reliable data for the effect of Testosterone Gel and of a combination ofNestorone® and Testosterone Gel on serum hormone levels.

与睾酮凝胶相比，评估雀巢酮和睾酮凝胶对促性腺激素的抑制作用。 28 天重复剂量研究的中心实验室 安全性和耐受性、药代动力学和 联合雀酮/睾酮凝胶在健康男性中的药效学研究 该任务单的目的是获得有关睾酮效果的有效且可靠的数据 凝胶以及 Nestorone® 和睾酮凝胶的组合对血清激素水平的影响。