P30-CENTER CORE GRANT FOR VISION RESEARCH

P30-中心视觉研究核心拨款

• 批准号: 8720773
• 负责人: ROBERT E ANDERSON
• 金额: $ 55.13万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8720773
• 关键词: Achievement; Animals; Area; Cancer Center Support Grant; Cellular biology; Center Core Grants; Centers of Research Excellence; Collaborations; Computer software; Core Facility; Development; Endocrinology; Environment; Equipment; Faculty; Fostering; Functional Imaging; Funding; Goals; Grant; Hand; Health; Housing; Human Resources; Imaging Techniques; Individual; Interview; Laboratories; Life; Location; Measures; Medicine; Mission; Nursing Faculty; Ophthalmology; Paper; Productivity; Qualifying; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resources; Scientist; Services; Structure; System; Training; Training Support; Translational Research; Vision; Vision research; base; cellular imaging; clinically relevant; data acquisition; experience; non-invasive imaging; operation; professor; ranpirnase

The goals of this proposal are to create, manage and maintain core facilities that will provide technical support, equipment access and personnel training for supported modules. We will establish two core modules including Live Animal Imaging and Functional Analysis, and Cellular Imaging and Morphometric Analysis Modules. These modules will be housed in convenient central locations, each containing state-of-the-art resources operated by highly qualified and well trained technicians that are supervised by junior faculty level Systems Managers and experienced senior vision researchers. The availability of multiple types of advanced equipment, sophisticated software, and "hands on" training will dramatically increase the quality and quantity of research achievements by the users of our Vision Core Grant facilities. Successful operation of these core facilities will: 1) increase opportunities for rigorous translational research using clinically relevant and non-invasive imaging procedures, 2) generate more collaborative projects that require multiple areas of expertise, 3) increase and enhance productivity of existing research projects thereby allowing participating investigators to remain competitive for funding, 4) promote recruitment of additional faculty, including two clinician scientists whom we are currently interviewing and 5) support the development of new research strategies based on the acquisition of data from the use of equipment previously unavailable to the PI's.

该提案的目标是创建、管理和维护核心设施，为支持的模块提供技术支持、设备访问和人员培训。我们将建立两个核心模块：活体动物成像和功能分析模块，细胞成像和形态计量分析模块。这些模块将被安置在方便的中心位置，每个模块都包含由高素质和训练有素的技术人员操作的最先进的资源，这些技术人员由初级教员级系统经理和经验丰富的高级视觉研究人员监督。多种类型的先进设备，复杂的软件和“动手”培训的可用性将大大提高我们的愿景核心资助设施的用户的研究成果的质量和数量。这些核心设施的成功运作将：1)增加使用临床相关和非侵入性成像程序进行严格转化研究的机会；2)产生更多需要多领域专业知识的合作项目；3)增加和提高现有研究项目的生产力，从而使参与的研究人员在资金方面保持竞争力；包括我们目前正在采访的两位临床科学家，他们支持开发新的研究策略，这些策略是基于使用PI以前无法使用的设备获取数据。