Dissemination of Patient-Centered Outcomes Research in Hepatitis C Virus to Infec

传播以患者为中心的丙型肝炎病毒感染结果研究

• 批准号: 8464492
• 负责人: David L Thomas
• 金额: $ 10万
• 依托单位: INFECTIOUS DISEASES SOCIETY OF AMERICA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-04-01 至 2016-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8464492
• 关键词: Dissemination; Patient; Centered; Outcomes; Research

DESCRIPTION (provided by applicant): 1 Dissemination of HCV Patient-Centered Outcomes Research - 2 Background: In the United States, nearly 4 million persons are estimated to be infected with 3 hepatitis C virus (HCV) with approximately 20,000 newly infected cases occurring each year.i,ii 4 Department of Health and Human Services has issued an action plan for the prevention, care 5 and treatment of viral hepatitis which aims to raise awareness of this "silent epidemic" and 6 reduce the number of new HCV infection cases, all in alignment with the Healthy People 2020 7 objectives.iii One major response is supported by recent research into the cost-effectiveness of 8 screening that has led the CDC to formulate new HCV screening guidelines that will call for the 9 testing of every person born 1945-1965. These new guidelines are expected to be released 10 later this year and will markedly increase HCV identification. 11 AHRQ has produced several complementary reviews focused on HCV screening, treatment, 12 and adherence to therapy. The rapid dissemination of this information to ID specialists is the 13 next critical step but requires resources to do so in a timely and effective manner. 14 The overarching goal of this program proposal is to reduce the morbidity and mortality 15 associated with HCV infection by expanding the capacity of ID providers to identify and treat 16 HCV infection. In order to achieve this goal, the IDSA's Hepatitis C Task Force will develop 17 educational programs and resources to assist ID specialists and fellows in the diagnosis, 18 management, and treatment of viral hepatitis. Specifically, the task force will (1) develop in- 19 depth training for ID specialists in the form of self-evaluation knowledge modules; (2) provide 20 training for ID fellows focused on the epidemiology, diagnosis, management, and treatment of 21 HCV, significantly expanding that which they may receive through their training programs; and 22 (3) provide outreach to the primary care community to promote HCV screening guidelines and 23 linkage to care following diagnosis. 24 This proposal will directly support the achievement of two of the Healthy People 2020 goals 25 related to hepatitis C virus - the goal of increasing the awareness of those infected and the goal 26 of decreasing the number of new infections. There is a high likelihood of success given the 27 timing of the rapid changes in the field of HCV and proven capability of IDSA to impact the 28 practice patterns of their membership through educational activities such as the specific 29 measures planned in this proposal. i Armstrong GL, Wasley A, Simard EP, McQuillan GM, Kuhnert WL, Alter MJ. The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Ann Intern Med 2006; 144:705-14. ii CDC. Surveillance for acute viral hepatitis-United States, 2008. Available at: http://www.cdc.gov/hepatitis/Statistics/2008Surveillance/index.htm. iii Combating the Silent Epidemic of Viral Hepatitis: Action Plan for Prevention, Care and Treatment of Viral Hepatitis. Department of Health & Human Services. May 12, 2011. Accessed on January, 17, 2012 at http://www.hhs.gov/ash/initiatives/hepatitis

描述（申请人提供）：1 HCV以患者为中心的结局研究的传播- 2背景：在美国，估计有近400万人感染丙型肝炎病毒（HCV），每年约有20，000例新感染病例。i，ii 4卫生与公众服务部已发布预防行动计划，病毒性肝炎的护理和治疗，旨在提高人们对这种“沉默的流行病”的认识，并减少新的HCV感染病例，所有这些都符合《2020年健康人》的7项目标。iii最近对成本的研究支持了一项主要对策-这导致CDC制定了新的HCV筛查指南，要求对1945-1965年出生的每个人进行9次检测。这些新的指南预计将于今年晚些时候发布，并将显着增加HCV的识别。11 AHRQ已经进行了几次补充审查，重点是HCV筛查，治疗，12和坚持治疗。迅速向身份证专家传播这一信息是下一个关键步骤，但需要资源来及时有效地这样做。14该计划提案的总体目标是通过扩大身份证提供者识别和治疗16 HCV感染的能力，降低与HCV感染相关的发病率和死亡率15。为了实现这一目标，IDSA的丙型肝炎工作组将开发17个教育项目和资源，以帮助ID专家和研究员诊断，18管理和治疗病毒性肝炎。具体而言，该工作组将（1）以自我评估知识模块的形式为ID专家开发19个深度培训;（2）为ID研究员提供20个培训，重点是21个HCV的流行病学，诊断，管理和治疗，显着扩大他们可能通过培训计划获得的内容;和22（3）向初级保健社区提供外展服务，以促进HCV筛查指南和23诊断后护理的联系。24该提案将直接支持实现2020年健康人群目标中与丙型肝炎病毒相关的两个目标25-提高感染者的意识和减少新感染人数的目标26。鉴于丙型肝炎病毒领域迅速变化的时机，以及IDSA通过教育活动（如本提案中计划的29项具体措施）对其成员的28种实践模式产生影响的能力，成功的可能性很高。i Armstrong GL，Wasley A，Simard EP，McQuillan GM，Kuhnert WL，Alter MJ. 1999年至2002年美国丙型肝炎病毒感染的患病率《内科学年鉴》2006; 144：705-14。ii CDC。急性病毒性肝炎的监测-美国，2008年。可在以下网址获得：http://www.cdc.gov/hepatitis/Statistics/2008Surveillance/index.htm。三.防治隐性病毒性肝炎：预防、护理和治疗病毒性肝炎行动计划。 卫生与公众服务部。2011年5月12日。2012年1月17日访问http://www.hhs.gov/ash/initiatives/hepatitis