权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Implementation of an Elementary and Robust Implantable Sensor for Musculoskeletal

用于肌肉骨骼的基本且稳健的植入式传感器的实现

基本信息

批准号：
8629693
负责人：
ERIC H LEDET
金额：
$ 19.83万
依托单位：
RENSSELAER POLYTECHNIC INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-04-01 至 2016-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8629693
关键词：
Activities of Daily Living Animal Model Arthrodesis Back Biomechanics Caliber Caregivers Caring Cervical Cervical spine Clinical Clinical Research Custom Data Diagnosis Diagnostic Economic Burden Electronics Fracture Healing Frequencies Goat Harvest Healed Health Histology Housing Implant Individual Insula of Reil Intervertebral disc structure Joints Life Link Measures Medical Medicine Modification Motion Muscle Musculoskeletal Musculoskeletal Diseases Orthopedics Outcome Patient Care Patients Pattern Performance Physical environment Posture Reading Recurrence Rehabilitation therapy Reporting Research Saline Sampling Spinal Spinal Fusion Spinal Injuries System Technology Telemetry Temperature Testing Thick Time Tissues Treatment Protocols United States Vertebral column Wireless Technology Work base biomaterial compatibility burden of illness clinical application clinical practice clinically relevant cost healing improved in vivo in vivo Model instrument meetings novel outcome forecast pre-clinical pressure public health relevance response sensor time use tool

项目摘要

DESCRIPTION (provided by applicant): The clinical utility of smart implants to facilitate personalized medicine in musculoskeletal disease is vast. On a patient-specific basis, the implant's physical environment provides a wealth of diagnostic data regarding the progression of healing and prognosis of an outcome. Customized care through personalized medicine reduces costs and improves outcomes by facilitating better diagnoses and optimal treatment regimens for individual patients. Previous smart implant systems used for research have not been adaptable to daily clinical practice due to complexity, cost, and the required modification of host implants. In this project, we will develop and implement a simple, robust, inexpensive, battery-less, telemetry-less, single component implantable sensor with no electrical connections for musculoskeletal smart implants. We will demonstrate that the sensor meets the criteria to facilitate personalized musculoskeletal medicine in daily clinical practice. The sensors will be integrated into spinal implants to (a) objectively correlate in vivo force to progress of spinal fusion, and (b) quantify real time in vivo multi-axial interbody force (axial and shear) during dynamic activities in the goat cervical spine.

描述（由申请人提供）：智能植入物在促进肌肉骨骼疾病个性化医疗方面的临床应用是巨大的。在患者特异性的基础上，植入物的物理环境提供了大量关于愈合进展和预后的诊断数据。通过个性化医疗的定制护理，通过促进对个体患者的更好诊断和最佳治疗方案，降低了成本并改善了结果。以前用于研究的智能植入系统由于复杂性、成本和需要的修改而不能适应日常临床实践

项目成果

期刊论文数量（5）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Smart implants in orthopedic surgery, improving patient outcomes: a review.

DOI：
10.2147/ieh.s133518
发表时间：
2018
期刊：
Innovation and entrepreneurship in health
影响因子：
0
作者：
Ledet EH;Liddle B;Kradinova K;Harper S
通讯作者：
Harper S

Simple implantable wireless sensor platform to measure pressure and force.

DOI：
10.1016/j.medengphy.2018.06.006
发表时间：
2018-09
期刊：
Medical engineering & physics
影响因子：
2.2
作者：
Drazan JF;Abdoun OT;Wassick MT;Dahle R;Beardslee L;Marcus GA;Cady NC;Ledet EH
通讯作者：
Ledet EH

Archimedean Spiral Pairs with no Electrical Connections as a Passive Wireless Implantable Sensor.

没有电气连接的阿基米德螺旋对作为无源无线植入传感器。

DOI：
发表时间：
2014
期刊：
Journal of biomedical technology and research
影响因子：
0
作者：
Drazan,JohnF;Gunko,Aleksandra;Dion,Matthew;Abdoun,Omar;Cady,NathanielC;Connor,KennethA;Ledet,EricH
通讯作者：
Ledet,EricH

A simple sensing mechanism for wireless, passive pressure sensors.

一种用于无线无源压力传感器的简单传感机制。