Computational and Technical Support for Clinical Trials and Physics Research for

临床试验和物理研究的计算和​​技术支持

• 批准号: 8716861
• 负责人: Hanne M Kooy
• 金额: $ 8.72万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 2019-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8716861
• 关键词: Adverse effects; Cancer Patient; Caring; Charge; Clinical; Clinical Trials; Clinical effectiveness; Clinical trial protocol document; Data Base Management; Dependency; Development; Dose; Enrollment; Funding; Grant; Instruction; Intensity-Modulated Radiotherapy; Licensing; Malignant Neoplasms; Mission; Modeling; Normal tissue morphology; Participant; Patients; Performance; Photons; Physics; Protocols documentation; Protons; Public Domains; Public Health; Radiation; Research; Resources; Safety; Services; System; Technology; Time; Treatment Protocols; Uncertainty; United States; Validation; Work; advanced system; base; cloud based; computing resources; design; dosimetry; improved; infrastructure development; particle; programs; proton beam; proton therapy; quality assurance; simulation; treatment planning; tumor; verification and validation

This core C provides services, developments and infrastructure to support: (1) treatment planning and delivery activities for MGH for patients enrolled on clinical trial protocols, including protocol treatments using IMRT, 3D CRT and SOBP and PBS treatment fields; (2) quality, dosimetry and technical validation of protocol design and delivery, including quantifying workflow efficiencies and analysis of workflow safety modes; (3) advancement of optimization technologies in support of PBS treatment planning in the presence of time-dependencies and physical uncertainties; (5) a framework for development and deployment of treatment planning and verification resources in support of the above aims; and (5) Cloud-based access for other POI participating centers to deployed resources. This core supports the mission of the NCI to improve the treatment and continuing care of cancer patients.

该核心C提供服务、开发和基础设施，以支持：(1)治疗计划和