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Project Summary: Metastasis is a multi-step process that involves multiple different tissue components supporting a heterotopic cancer cell. We propose that mesenchymal cell interactions with cancer cells play a critical role in the successful engraftment of the cancer in a metastatic site. We will test that hypothesis through the examination and manipulafion of specific subsets of mesenchymal cells interacting with primary prostate cancer cells of defined genotype. PHS
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Functional consequences of stem and progenitor cell heterogeneity
  • 批准号:
    10413502
  • 项目类别:
  • 资助金额:
    $5.04万
  • 财政年份:
    2020
  • 负责人:
    David T Scadden
  • 依托单位:
Enhancing regeneration of stem cell-derived HIV-specific immune effectors
  • 批准号:
    10409803
  • 项目类别:
  • 资助金额:
    $55.27万
  • 财政年份:
    2020
  • 负责人:
    David T Scadden
  • 依托单位:
Enhancing regeneration of stem cell-derived HIV-specific immune effectors
  • 批准号:
    10163909
  • 项目类别:
  • 资助金额:
    $49.97万
  • 财政年份:
    2020
  • 负责人:
    David T Scadden
  • 依托单位:
Clonal tracking and molecular characterization of hematopoiesis under stress
  • 批准号:
    10413504
  • 项目类别:
  • 资助金额:
    $5.04万
  • 财政年份:
    2020
  • 负责人:
    David T Scadden
  • 依托单位:
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