2013 Myogenesis Gordon Research Conference and Gordon Research Seminar

描述(由申请人提供)：本提案请求部分支持2013年7月6-12日在意大利卢卡文艺复兴托斯卡纳Il Ciocco度假村举行的戈登研究会议和戈登研究研讨会系列的一部分，关于肌肉发生的国际会议。会议和研讨会的广泛和长期目标是增加我们对正常肌肉发育、生长和肥大、再生、动态平衡和衰老、癌症和肌病以及进化的基本机制的理解，重点放在哺乳动物模型上，但与其他脊椎动物和无脊椎动物系统进行比较。这些会议的具体目标是：1.在孤立的环境下召开一次有45名发言者参加的会议，代表横纹肌研究的关键领域，总共200名与会者参加为期5天的会议；以及2.在会议之前举行一次为期一天的研究生和博士后研究讨论会。会议计划将有关于肌肉骨骼发育和进化的主旨演讲和九场会议，广泛讨论肌肉早期发育的细胞生物学控制、调节肌肉发育和再生的组织相互作用、肌肉大小的调节、肌肉干细胞、遗传、表观遗传学和肌肉的MicroRNA控制、肌肉再生和衰老以及肌肉疾病和治疗方面的当前问题。此外，四次晚间海报会议将允许所有参与者为这些主题作出贡献。研讨会将由研究生和博士后研究员进行四次演讲和两次海报会议，为即将到来的一代科学家展示他们在肌肉发生方面的研究、开发新想法和形成合作提供了一个独特的机会。这一应用的意义在于，肌肉发生戈登研究会议是每年一次的会议的重要组成部分，这些会议汇集了国际社会的尖端肌肉研究人员。首届戈登-凯南研究生和博士后研究研讨会是一次令人兴奋的新会议，旨在培养肌肉发生领域的下一代科学家。这一应用的与健康相关的是，在这一跨学科会议中产生的讨论将定义该领域当前的悬而未决的问题，并将在影响人类肌肉发育、健康和衰老、肌肉疾病以及再生机制和治疗的领域产生新的实验方法。

DESCRIPTION (provided by applicant): This proposal requests partial support for an international meeting on Myogenesis as part of the Gordon Research Conference and Gordon Research Seminar series to be held at the Renaissance Tuscany Il Ciocco Resort Lucca (Barga), Italy July 6-12, 2013. The broad and long term goal of the conference and seminar is to increase our understanding of the fundamental mechanisms of normal muscle development, growth and hypertrophy, regeneration, homeostasis and aging, cancer and myopathies, and evolution with an emphasis on mammalian models but with comparisons to other vertebrate and invertebrate systems. The specific aims of these meetings are to convene, in an isolated setting, 1. a Conference with 45 speakers that represent critical areas of striated muscle research with a total of 200 participants for a five day conference as well as 2. a one day graduate and postdoctoral research Seminar immediately prior to the Conference. The Conference program will have a keynote address on musculoskeletal development and evolution, and nine sessions that broadly address current issues in early muscle development, cell biological control of myogenesis, tissue interactions regulating muscle development and regeneration, regulation of muscle size, muscle stem cells, genetic, epigenetic, and microRNA control of muscle, muscle regeneration and aging, and muscle disease and treatments. In addition, four evening poster sessions will permit all participants to contribute to these topics. The Seminar will have four sessions of talks and two poster sessions by graduate students and postdoctoral fellows and represents a unique opportunity for the upcoming generation of scientists to present their research on myogenesis, develop new ideas, and form collaborations. The significance of this application is that the Myogenesis Gordon Research Conference is a critical component of the yearly series of conferences that bring together cutting edge muscle researchers in the international community. The inaugural Gordon-Kenan Graduate and Postdoctoral Research Seminar is an exciting new meeting to foster the upcoming generation of scientists in the field of myogenesis. The health relatedness of this application is that the discussions generated within this interdisciplinary conference will define current outstanding questions in the field and will generate new experimental approaches in areas that affect human muscle development, health, and aging, muscle diseases, and regenerative mechanisms and therapies.