Direct catalytic C-C coupling via transfer hydrogenation

通过转移氢化直接催化 C-C 偶联

• 批准号: 8652109
• 负责人: Brannon Sam
• 金额: $ 3.63万
• 依托单位: UNIVERSITY OF TEXAS AT AUSTIN
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-01-22 至 2015-01-21
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8652109
• 关键词: Alcohols; Aldehydes; Amines; Biological Factors; Catalysis; Chemistry; Complex; Coupling; Data; Development; FDA approved; Funding; Funding Opportunities; Generations; Goals; Hydrogenation; Investigation; Iridium; Laboratories; Metals; Methods; Organic Chemistry; Organic Synthesis; Oxidation-Reduction; Process; Reagent; Reporting; Research; Research Training; Ruthenium; Scheme; Students; Techniques; Therapeutic Agents; Training; Training Programs; Transition Elements; catalyst; dehydrogenation; improved; oxidation; public health relevance; skills; small molecule

DESCRIPTION (provided by applicant): The main objective of the proposed funding period is to train Mr. Brannon Sam, such that he is competitive in the field of organic chemistry at the highest national level. Undertaking such a challenge as the proposed project in catalytic C-C bond formation of amines and unsaturates allows for the development of the skills needed to advance modern chemistry, particularly in regards to complex molecules synthesis. The proposed project will promote Brannon's autonomy by improving his abilities to think critically, interpret and present data, and employ organic synthesis technique. He will gain a deeper understanding of transition-metal catalysis and small-molecule synthesis. Brannon will be the only student trained under this funding opportunity, and there will be approximately 20 students in the laboratory that he will interact with.

描述(由申请人提供)：拟议资助期的主要目标是培训Brannon Sam先生，使他在国家最高级别的有机化学领域具有竞争力。承担像拟议的胺和不饱和化合物催化C-C键形成项目这样的挑战，可以发展促进现代化学所需的技能，特别是在复杂分子合成方面。拟议中的项目将通过提高布兰农批判性思维、解释和呈现数据以及使用有机合成技术的能力来促进他的自主性。他将对过渡金属催化和小分子合成有更深的理解。Brannon将是唯一一名根据这一资助机会接受培训的学生，实验室中将有大约20名学生与他互动。