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The Role of Economic Evaluation in Translating HIV/AIDS Behavioral Interventions

经济评估在艾滋病毒/艾滋病行为干预措施转化中的作用

基本信息

批准号：
8596851
负责人：
Jose Luis Burgos
金额：
$ 18.04万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-01-01 至 2016-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8596851
关键词：
AIDS prevention AIDS/HIV problem Area Attitude Behavior Therapy Behavioral Behavioral Sciences Belief California Cities Collection Communities Complement Cost Effectiveness Analysis Counseling Data Data Collection Decision Making Development Economics Educational workshop Effectiveness Ensure Ethics Evaluation Research Evaluation Studies Exposure to Female Funding Goals Government Grant Guidelines HIV HIV Infections Health Care Costs Health Policy Incidence Individual Infection prevention Institution Intention International Intervention Interview K-Series Research Career Programs Knowledge Lead Life Mediation Mentors Mentorship Methods Mexican Mexico National Institute of Mental Health Operations Research Outcome Persons Policies Policy Maker Populations at Risk Positioning Attribute Prevalence Prevention Guidelines Preventive Intervention Private Sector Process Program Effectiveness Program Evaluation Provider Public Policy Public Sector Qualitative Methods Questionnaires Randomized Controlled Trials Reading Research Research Methodology Research Personnel Research Training Role Sampling Scientist Services Sexually Transmitted Diseases Social Network Staging Training Training Activity Translating Translational Research Translations Underserved Population United States National Institutes of Health Universities Vulnerable Populations Woman Work base career community setting condoms control trial cost cost effective cost effectiveness density design economic evaluation ethnic minority population evidence base experience improved operation parent grant research study safer sex scale up sex skills theories

项目摘要

DESCRIPTION (provided by applicant): The purpose of the proposed Mentored Scientist Career Development Award (K01) is to provide the candidate with mentoring and research experiences that will promote his development as an independent researcher, with particular emphasis in operations and translational research of evidence based (EB) HIV prevention behavioral interventions among vulnerable populations. The objectives of the training are to develop knowledge and skills in: 1) qualitative and mixed methods research to understand the decision-making process among policy makers as it relates to HIV prevention policies; 2) expertise in operations research of EB HIV prevention intervention in international settings; 3) advanced methods for cost-effectiveness analysis; 4) theory-driven behavioral HIV prevention interventions among vulnerable populations and 5) additional training in the ethical conduct of research among vulnerable populations. Training activities will include didactic coursework and specific workshops, directed readings and one-on-one tutorials with mentors. The candidate will receive mentorship from a training committee comprised of internationally renowned experts in the fields of translational research, behavioral science, and mixed methods research at the University of California San Diego. The specific aims of the proposed research are to: 1) qualitatively describe policy makers' perspectives vis-`-vis institutional, political, cultural and individual factors that facilitate or impede the use of economic evaluation research in translating EB behavioral interventions into health policy; 2) To quantitatively characterize Mexican government and community based organizations (CBO) policy-makers' knowledge, attitudes and the experience of translating results from economic evaluation research into policy decisions; 3) To estimate the programmatic cost-effectiveness of the Mujer Segura behavioral intervention, shown to reduce HIV and sexually transmitted infections (STIs) among female sex workers (FSWs) in Mexico during the large scale implementation process compared to current Mexican HIV/STI prevention guidelines. The research aims will be accomplished by conducting a mixed methods research study. Quantitative data will be drawn from the operations costs and health outcomes of the upscale implementation of an efficacious intervention (Mujer Segura) among 960 FSWs in twelve different cities in Mexico (National Institute of Mental Health grant titled: "Implementation of an efficacious intervention for Female Sex Workers in Mexico"; R01MH08754; PI: Patterson; Co-I: Dr. Strathdee). Qualitative data will be collected from in-depth interviews of a sample of 40 policy makers from governmental institutions and CBOs involved in HIV prevention in Mexico. Findings from the proposed research will position the candidate to propose an R01 proposal for in depth study of HIV policy maker's decision making process in HIV translation. Moreover, the candidate's binational and ethnic minority background combined with the proposed training and research will support a career trajectory focused on vulnerable, underserved populations at risk for HIV infection.

描述（由申请人提供）：拟议的指导科学家职业发展奖（K 01）的目的是为候选人提供指导和研究经验，以促进他作为独立研究人员的发展，特别强调循证（EB）的运营和转化研究弱势群体中的艾滋病毒预防行为干预措施。培训的目标是发展以下方面的知识和技能：1）定性和混合方法研究，以了解决策者之间的决策过程，因为它涉及艾滋病毒预防政策; 2）在国际环境中EB艾滋病毒预防干预的业务研究专业知识; 3）先进的成本效益分析方法; 4）在弱势群体中进行理论驱动的艾滋病毒预防行为干预，5）在弱势群体中进行伦理研究方面的额外培训。培训活动将包括教学课程和具体研讨会、指导阅读和与导师的一对一辅导。候选人将接受培训委员会的指导，该委员会由加州圣地亚哥大学转化研究、行为科学和混合方法研究领域的国际知名专家组成。拟议研究的具体目标是：1）定性地描述政策制定者维斯体制、政治、文化和促进或阻碍经济评价研究在翻译中应用的个别因素 2）定量描述墨西哥政府和社区组织（CBO）决策者的知识、态度和将经济评估研究结果转化为政策决定的经验; 3）评估妇女塞古拉行为干预的方案成本效益，与目前的墨西哥艾滋病毒/性传播感染预防指南相比，在大规模实施过程中，墨西哥女性性工作者（FSW）中的艾滋病毒和性传播感染（STI）有所减少。研究目的将通过进行混合方法的研究来实现。将从墨西哥12个不同城市的960名女性性工作者中大规模实施有效干预（妇女塞古拉）的运营成本和健康结果中提取定量数据（国家心理健康研究所赠款，标题为：“在墨西哥实施对女性性工作者的有效干预”; R 01 MH 08754; PI：Patterson; Co-I：Dr. Strathdee）。定性数据将从对墨西哥参与艾滋病毒预防工作的政府机构和社区组织的40名决策者的抽样深入访谈中收集。从拟议的研究结果将定位候选人提出一个R 01建议，深入研究艾滋病毒政策制定者的决策过程中的艾滋病毒翻译。此外，候选人的两国和少数民族背景，加上拟议的培训和研究，将有助于其职业轨迹侧重于易受艾滋病毒感染、得不到充分服务的弱势群体。