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The Role of Economic Evaluation in Translating HIV/AIDS Behavioral Interventions

经济评估在艾滋病毒/艾滋病行为干预措施转化中的作用

基本信息

批准号：
8785134
负责人：
Jose Luis Burgos
金额：
$ 18.04万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-01-01 至 2015-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8785134
关键词：
AIDS prevention AIDS/HIV problem Area Attitude Behavior Therapy Behavioral Behavioral Sciences Belief California Cities Collection Communities Complement Cost Effectiveness Analysis Counseling Data Data Collection Decision Making Development Economics Educational workshop Effectiveness Ensure Ethics Evaluation Research Evaluation Studies Exposure to Female Funding Goals Government Grant Guidelines HIV HIV Infections Health Care Costs Health Policy Incidence Individual Infection prevention Institution Intention International Intervention Interview K-Series Research Career Programs Knowledge Lead Life Mediation Mentors Mentorship Methods Mexican Mexico National Institute of Mental Health Operations Research Outcome Persons Policies Policy Maker Populations at Risk Positioning Attribute Prevalence Prevention Guidelines Preventive Intervention Private Sector Process Program Effectiveness Program Evaluation Provider Public Policy Public Sector Qualitative Methods Questionnaires Randomized Controlled Trials Reading Research Research Methodology Research Personnel Research Training Role Safe Sex Sampling Scientist Services Sexually Transmitted Diseases Social Network Staging Training Training Activity Translating Translational Research Translations Underserved Population United States National Institutes of Health Universities Vulnerable Populations Woman Work base career community setting condoms control trial cost cost effective cost effectiveness density design economic evaluation ethnic minority population evidence base experience improved operation parent grant research study scale up sex skills theories

项目摘要

DESCRIPTION (provided by applicant): The purpose of the proposed Mentored Scientist Career Development Award (K01) is to provide the candidate with mentoring and research experiences that will promote his development as an independent researcher, with particular emphasis in operations and translational research of evidence based (EB) HIV prevention behavioral interventions among vulnerable populations. The objectives of the training are to develop knowledge and skills in: 1) qualitative and mixed methods research to understand the decision-making process among policy makers as it relates to HIV prevention policies; 2) expertise in operations research of EB HIV prevention intervention in international settings; 3) advanced methods for cost-effectiveness analysis; 4) theory-driven behavioral HIV prevention interventions among vulnerable populations and 5) additional training in the ethical conduct of research among vulnerable populations. Training activities will include didactic coursework and specific workshops, directed readings and one-on-one tutorials with mentors. The candidate will receive mentorship from a training committee comprised of internationally renowned experts in the fields of translational research, behavioral science, and mixed methods research at the University of California San Diego. The specific aims of the proposed research are to: 1) qualitatively describe policy makers' perspectives vis-`-vis institutional, political, cultural and individual factors that facilitate or impede the use of economic evaluation research in translating EB behavioral interventions into health policy; 2) To quantitatively characterize Mexican government and community based organizations (CBO) policy-makers' knowledge, attitudes and the experience of translating results from economic evaluation research into policy decisions; 3) To estimate the programmatic cost-effectiveness of the Mujer Segura behavioral intervention, shown to reduce HIV and sexually transmitted infections (STIs) among female sex workers (FSWs) in Mexico during the large scale implementation process compared to current Mexican HIV/STI prevention guidelines. The research aims will be accomplished by conducting a mixed methods research study. Quantitative data will be drawn from the operations costs and health outcomes of the upscale implementation of an efficacious intervention (Mujer Segura) among 960 FSWs in twelve different cities in Mexico (National Institute of Mental Health grant titled: "Implementation of an efficacious intervention for Female Sex Workers in Mexico"; R01MH08754; PI: Patterson; Co-I: Dr. Strathdee). Qualitative data will be collected from in-depth interviews of a sample of 40 policy makers from governmental institutions and CBOs involved in HIV prevention in Mexico. Findings from the proposed research will position the candidate to propose an R01 proposal for in depth study of HIV policy maker's decision making process in HIV translation. Moreover, the candidate's binational and ethnic minority background combined with the proposed training and research will support a career trajectory focused on vulnerable, underserved populations at risk for HIV infection.

描述(由申请人提供)：拟议的指导型科学家职业发展奖(K01)的目的是为候选人提供指导和研究经验，以促进他作为独立研究人员的发展，特别强调基于证据的(EB)艾滋病毒预防行为干预在脆弱人群中的操作和转化研究。培训的目的是培养以下方面的知识和技能：1)定性和混合方法研究，以了解决策者在与艾滋病毒预防政策有关时的决策过程；2)国际环境下EB艾滋病毒预防干预行动研究的专门知识；3)成本效益分析的先进方法；4)脆弱人群中以理论为导向的行为艾滋病毒预防干预措施；5)在弱势人群中进行研究的伦理方面的额外培训。培训活动将包括授课课程和特定的研讨会，定向阅读和与导师的一对一辅导。候选人将接受一个培训委员会的指导，该委员会由加州大学圣地亚哥分校翻译研究、行为科学和混合方法研究领域的国际知名专家组成。拟议研究的具体目的是：1)定性地描述政策制定者在体制、政治、文化和社会各方面的观点促进或阻碍经济评价研究在翻译中使用的个别因素其目的是将行为干预纳入卫生政策；2)定量描述墨西哥政府和社区组织(CBO)政策制定者的知识、态度和将经济评估研究结果转化为政策决策的经验；3)评估Mujer Segura行为干预的方案成本效益，与墨西哥目前的艾滋病毒/性传播感染预防指南相比，该干预措施在大规模实施过程中可减少墨西哥女性性工作者中的艾滋病毒和性传播感染(STI)。研究目标将通过开展混合方法研究来实现。量化数据将来自在墨西哥12个不同城市的960名FSWs中实施有效干预(Mujer Segura)的业务成本和健康结果(国家心理健康研究所赠款题为：“对墨西哥女性性工作者实施有效干预”；R01MH08754；PI：Patterson；Co-I：Dr.Strathdee)。定性数据将从对墨西哥参与艾滋病毒预防的政府机构和社区组织的40名政策制定者的深入访谈中收集。拟议研究的结果将使候选人能够提出R01提案，以深入研究艾滋病毒政策制定者在艾滋病毒翻译中的决策过程。此外，候选人的两国背景和少数民族背景，加上拟议的培训和研究，将支持专注于易受感染艾滋病毒的弱势、服务不足的人群的职业轨迹。