Maternal-Offspring Metabolics: Family Intervention Trial (MOMFIT)

在过去的二十年里，美国肥胖症的患病率急剧增加， 和过早的不良健康后果。育龄妇女，特别是少数民族和 社会经济地位低的妇女，由于妊娠期体重过重， 这进一步导致了儿童肥胖和糖尿病的惊人发病率。防止 过量的GWG可以减少妊娠并发症，改善妇女的长期健康， 后代怀孕期间的体重控制研究正在兴起，但大多数研究都是模仿传统的 通过饮食咨询和/或增加活动进行体重控制计划，但持续的证据有限 坚持。需要新的方法来限制体重增加到医学研究所（IOM）的目标， 帮助新妈妈们坚持推荐的饮食、体育活动和生活方式，让她们成为榜样 家人拟议的研究将开发和测试一种新的方法， 通过行为适应，营养丰富，能量平衡的生活方式预防肥胖， 临床实施，客观评估，并通过技术先进的自我监测长期持续 方法.这项随机对照临床试验与标准治疗进行了比较， 超重/肥胖的孕妇，参与生活方式干预， 指导和小组会议，以发展对推荐饮食和体育活动行为的自我监测 长期.将在产前评估人体测量、代谢、饮食、活动和生活方式结局， 分娩后至少12个月。西北妇产科提供护理 每年有超过12 000名不同种族的产科病人，其中许多人参加了临床试验， 由功能强大的产科研究基础设施提供便利。我们的多学科团队，经验丰富， 产科和预防研究，提出创新技术和加强自我监测技能， 记录新妈妈是否可以更好地准备发展和示范饮食和能量平衡 为他们的家庭和自己的生活方式行为，并减少和预防肥胖的长期。

The prevalence of obesity has increased dramatically in the US over the last two decades, with rapidly rising and premature adverse health consequences. Women of reproductive age, especially minorities and those of low socioeconomic status, are at risk of adverse pregnancy outcomes due to excessive gestational weight gain (GWG) and this further contributes to alarming rates of childhood obesity and diabetes. Preventing excessive GWG could reduce pregnancy complications and improve long term health of women and their offspring. Weight control studies in pregnancy are emerging but most studies have emulated traditional weight control programs through diet counseling and/or increased activity with limited evidence of sustained adherence. Novel approaches are needed to limit weight gain to Institute of Medicine (IOM) goals, and to help new mothers adhere to recommended diet, physical activity and lifestyle behaviors they can model for their families. The proposed research will develop and test a new approach to primary and secondary prevention of obesity through a behaviorally adapted, nutrient-dense, energy-balanced lifestyle that can be implemented clinically, assessed objectively and sustained long term through technologically-advanced selfmonitoring methods. This randomized controlled clinical trial compares with standard care, the GWG of overweight / obese pregnant women who participate in lifestyle intervention with individualized, motivational coaching and group sessions to develop self-monitoring of recommended diet and physical activity behavior long term. Anthropometric, metabolic, diet, activity and lifestyle outcomes will be assessed prenatally and for at least 12 months post delivery. The Northwestern Department of Obstetrics and Gynecology provides care for over 12,000 ethnically diverse obstetric patients a year, many of whom participate in clinical trials, facilitated by a highly functional obstetric research infrastructure. Our multidisciplinary team, experienced in obstetrics and prevention research, propose innovative technology and enhanced self-monitoring skills to document whether new mothers can be better prepared to develop and model diet and energy-balanced lifestyle behaviors for their families and themselves and reduce and prevent obesity long term.