Maternal-Offspring Metabolics: Family Intervention Trial (MOMFIT)
Maternal-Offspring Metabolics: Family Intervention Trial (MOMFIT)
批准号:
8526543
负责人:
ALAN M PEACEMAN
金额:
$73.6万
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-09-23 至 2017-02-28
关键词:
AchievementAdherenceAgeAirAmericanBehaviorBehavior TherapyBeveragesBiological AssayBirthBlood GlucoseBlood PressureBody CompositionBreast FeedingC-PeptideCaringCitrus FruitClinical TrialsCommunity HealthControl GroupsControlled StudyCounselingDiabetes MellitusDietDietary FiberDiscipline of obstetricsEffectivenessElectrocardiogramEnergy IntakeEquilibriumFamilyFatty acid glycerol estersFeedbackFiberFocus GroupsFoodFrequenciesGestational AgeGestational DiabetesGoalsGuidelinesGynecologyHealthHealth EducatorsHispanicsHourInfantInstitute of Medicine (U.S.)InstructionInsulinIntakeIntervention TrialLengthLife StyleLipidsMeasuresMetabolicMethodsMinorityModelingMonitorMothersNewborn InfantNutrientObesityOutcomeOutputOverweightParticipantPatientsPhysical activityPlethysmographyPopulationPostpartum PeriodPre-EclampsiaPregnancyPregnancy ComplicationsPregnancy OutcomePregnant WomenPrevalencePrevention ResearchPrimary PreventionProteinsQuestionnairesRandomizedRandomized Controlled Clinical TrialsRecruitment ActivityReportingResearchResearch InfrastructureRiskSecondary PreventionSeveritiesSleepSolidStressSulfoxideTestingTrainers TrainingUmbilical Cord BloodUrineWeightWeight GainWeight maintenance regimenWomanWomen&aposs Healthbehavior measurementcardiovascular risk factorcruciferous vegetableenergy balanceexperiencefasting glucosefruits and vegetablesimprovedinnovative technologiesintervention programlifestyle interventionlow socioeconomic statusmetabolomicsmultidisciplinarynovel strategiesobesity in childrenoffspringprematureprenatalpreventprogramsracial and ethnicreproductivesafety testingskillssocioeconomicsstandard caretrial comparing
中文摘要
在过去的二十年里,肥胖症在美国的流行程度急剧上升,而且还在迅速上升
以及过早的不良健康后果。育龄妇女,特别是少数群体和
社会经济地位低的人因妊娠体重过大而面临不良妊娠结局的风险
这进一步加剧了儿童肥胖率和糖尿病的惊人比率。预防
过量的GWG可以减少妊娠并发症,改善妇女和妇女的长期健康
后代。孕期体重控制研究正在兴起,但大多数研究都仿效了传统的
通过饮食咨询和/或增加活动来控制体重,但证据有限
坚持不懈。需要新的方法来限制体重增加到医学研究所(IOM)的目标,并
帮助新妈妈坚持她们可以效仿的推荐饮食、体力活动和生活方式行为
他们的家人。这项拟议的研究将开发和测试一种新的小学和中学教育方法
通过行为适应、营养密集、能量平衡的生活方式预防肥胖
通过技术先进的自我监测实现临床实施、客观评估和长期持续
方法:研究方法。这项随机对照临床试验与标准护理相比,GWG
参与个性化、激励性生活方式干预的超重/肥胖孕妇
指导和小组会议,以培养对推荐饮食和体力活动行为的自我监控
从长远来看。人体测量、新陈代谢、饮食、活动和生活方式的结果将在产前和
产后至少12个月。西北妇产科提供护理
每年有超过12,000名不同种族的产科患者,其中许多人参加临床试验,
在高度实用的产科研究基础设施的推动下。我们的多学科团队,在
产科和预防研究,提出创新技术和增强自我监测技能,以
记录新妈妈是否能更好地为饮食和能量平衡做好准备
为家人和自己的生活方式行为,并长期减少和预防肥胖。
英文摘要
The prevalence of obesity has increased dramatically in the US over the last two decades, with rapidly rising
and premature adverse health consequences. Women of reproductive age, especially minorities and those
of low socioeconomic status, are at risk of adverse pregnancy outcomes due to excessive gestational weight
gain (GWG) and this further contributes to alarming rates of childhood obesity and diabetes. Preventing
excessive GWG could reduce pregnancy complications and improve long term health of women and their
offspring. Weight control studies in pregnancy are emerging but most studies have emulated traditional
weight control programs through diet counseling and/or increased activity with limited evidence of sustained
adherence. Novel approaches are needed to limit weight gain to Institute of Medicine (IOM) goals, and to
help new mothers adhere to recommended diet, physical activity and lifestyle behaviors they can model for
their families. The proposed research will develop and test a new approach to primary and secondary
prevention of obesity through a behaviorally adapted, nutrient-dense, energy-balanced lifestyle that can be
implemented clinically, assessed objectively and sustained long term through technologically-advanced selfmonitoring
methods. This randomized controlled clinical trial compares with standard care, the GWG of
overweight / obese pregnant women who participate in lifestyle intervention with individualized, motivational
coaching and group sessions to develop self-monitoring of recommended diet and physical activity behavior
long term. Anthropometric, metabolic, diet, activity and lifestyle outcomes will be assessed prenatally and for
at least 12 months post delivery. The Northwestern Department of Obstetrics and Gynecology provides care
for over 12,000 ethnically diverse obstetric patients a year, many of whom participate in clinical trials,
facilitated by a highly functional obstetric research infrastructure. Our multidisciplinary team, experienced in
obstetrics and prevention research, propose innovative technology and enhanced self-monitoring skills to
document whether new mothers can be better prepared to develop and model diet and energy-balanced
lifestyle behaviors for their families and themselves and reduce and prevent obesity long term.
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Maternal-Offspring Metabolics: Family Intervention Trial (MOMFIT)
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批准号:8532548
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项目类别:
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资助金额:$5.0万
-
财政年份:2011
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负责人:ALAN M PEACEMAN
-
依托单位:
Maternal-Offspring Metabolics: Family Intervention Trial (MOMFIT)
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批准号:9123855
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项目类别:
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资助金额:$23.0万
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财政年份:2011
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负责人:ALAN M PEACEMAN
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依托单位:
Maternal-Offspring Metabolics: Family Intervention Trial (MOMFIT)
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批准号:8336921
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项目类别:
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资助金额:$76.21万
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负责人:ALAN M PEACEMAN
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批准号:9442252
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批准号:8830997
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项目类别:
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资助金额:$4.67万
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负责人:ALAN M PEACEMAN
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批准号:8920841
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资助金额:$13.9万
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财政年份:2011
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依托单位:
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批准号:8247940
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项目类别:
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资助金额:$76.81万
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财政年份:2011
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负责人:ALAN M PEACEMAN
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依托单位:
A RANDOMIZED CLINICAL TRIAL OF TREATMENT FOR GESTATIONAL DIABETES MELLITUS
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批准号:7604260
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项目类别:
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资助金额:$0.5万
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财政年份:2006
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负责人:ALAN M PEACEMAN
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依托单位:
A RANDOMIZED CLINICAL TRIAL OF TREATMENT FOR GESTATIONAL DIABETES MELLITUS
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资助金额:$0.89万
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财政年份:2005
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负责人:ALAN M PEACEMAN
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依托单位:
A RANDOMIZED CLINICAL TRIAL OF TREATMENT FOR GESTATIONAL DIABETES MELLITUS
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项目类别:
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资助金额:$1.2万
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财政年份:2004
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负责人:ALAN M PEACEMAN
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资助金额:$0.07万
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财政年份:2003
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负责人:ALAN M PEACEMAN
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依托单位:
NICHD Maternal Fetal Medicine Units Network
-
批准号:8251938
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项目类别:
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资助金额:$30.06万
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财政年份:2001
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负责人:ALAN M PEACEMAN
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依托单位:
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依托单位:
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财政年份:2001
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负责人:ALAN M PEACEMAN
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批准号:6889274
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项目类别:
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资助金额:$49.22万
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财政年份:2001
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负责人:ALAN M PEACEMAN
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依托单位:
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项目类别:
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资助金额:$8.67万
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负责人:ALAN M PEACEMAN
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依托单位:
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项目类别:
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资助金额:$85.57万
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负责人:ALAN M PEACEMAN
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依托单位:
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海外基金