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Nanoparticulate Coatings Enhance Ion Detection

纳米颗粒涂层增强离子检测

批准号：

8715209

负责人：

Ernest Kjell Lewis

金额：

$35.05万

依托单位：

IONWERKS, INC.

依托单位国家：

美国

项目类别：

财政年份：

2014

资助国家：

美国

项目状态：

已结题

起止时间：

2014-09-25 至 2015-12-24

来源：

https://reporter.nih.gov/project-details/8715209

关键词：

Alloys Biological Caliber Charge Collaborations Deposition Detection Electronics Electrons Employee Strikes Fast Electron Film Fluorescence Microscopy Future Goals Height Helium Housing Individual Ions Kinetics Mass Spectrum Analysis Measures Metals Microscope Microscopy Molecular Noble Gases Penetration Peptides Performance Photons Physiologic pulse Porosity Probability Radial Relative (related person)Rice Sales Semiconductors Solid Solutions Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Structure Surface System Techniques Testing Time Transmission Electron Microscopy Universities Vacuum base detector improved instrument ion mobility mass spectrometer nano nanoparticulate particle photonics public health relevance research study simulation

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DESCRIPTION (provided by applicant): A new thin film approach to increasing the gain and sensitivity of current and future fast particle detectors is hypothesized. An increased ion induced secondary electron yield at the first surface of the detector while retaining high timing accuracy will make such detectors suitable replacement for MCP detectors in biological applications such as electron or ion microscopies and time of flight mass spectrometers. Moreover, the detector may be sensitive to the energy or momentum of the incoming ion. Such information could simplify MALDI or electrospray MS spectra containing highly charged molecular ions.

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