Induction of HIV Neutralizing Antibodies by Targeting Macaque B Cell Receptors

通过靶向猕猴 B 细胞受体诱导 HIV 中和抗体

• 批准号: 8743681
• 负责人: MIROSLAW K GORNY
• 金额: $ 8.8万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-12-19 至 2015-12-18
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8743681
• 关键词: 3-Dimensional; Affinity; Animals; Antibodies; Antigens; Avidity; B-Lymphocytes; Binding; Binding Sites; Blood specimen; Cell Separation; Cells; Chimeric Proteins; Clinical Trials; Complementary DNA; Cyclic Peptides; DNA; Epitopes; Flow Cytometry; Genes; Goals; HIV; HIV Envelope Protein gp120; HIV vaccine; HIV-1; Human; Immune response; Immunization; Immunogenetics; Immunoglobulin G; Immunoglobulin Genes; Immunoglobulins; Individual; Infection; Inhibitory Concentration 50; Macaca; Macaca mulatta; Mediating; Monitor; Mutation; Peptides; Peripheral Blood Mononuclear Cell; Process; Production; Proteins; Receptors, Antigen, B-Cell; Regimen; Relative (related person); Reverse Transcriptase Polymerase Chain Reaction; Serum; Shapes; Somatic Mutation; Specificity; Specimen; Statistical Methods; Testing; Time; Vaccines; abstracting; antigen binding; base; design; env Gene Products; expression vector; gp160; immunoglobulin receptor; innovation; neutralizing antibody; neutralizing monoclonal antibodies; novel strategies; receptor; vaccine development

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