Immune-Based Interventions Against Infectious Diseases

针对传染病的免疫干预措施

• 批准号: 8727073
• 负责人: Alan L Rothman
• 金额: $ 186.44万
• 依托单位: UNIVERSITY OF RHODE ISLAND
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2018-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8727073
• 关键词: Academia; Address; Advanced Development; Antigens; Cause of Death; Cells; Centers of Research Excellence; Collaborations; Commit; Communicable Diseases; Communities; Disease; Emerging Communicable Diseases; Environment; Funding; Future; Health; Hospitals; Immune; Immune response; Immunology; Incubators; Industry; Infectious Disease Immunology; Informatics; Institutes; Interdisciplinary Study; Intervention; Knowledge; Leadership; Longevity; Mentors; Positioning Attribute; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Research Support; Rhode Island; Role; Sorting - Cell Movement; Technology; Therapeutic; Translational Research; United States National Institutes of Health; Universities; Vision; base; data management; experience; global health; high throughput analysis; innovation; interest; international center; multidisciplinary; pathogen; product development; programs; response; statistics

DESCRIPTION (provided by applicant): Infectious diseases continue to represent major causes of death and disease worldwide. Our strategy to address the challenge of new and emerging infectious diseases is to build a critical mass of investigators in infectious diseases immunology, committed to collaboration and innovation. The overall objective of this COBRE, "Immune-Based Interventions against Infectious Diseases," is to advance the development of a multidisciplinary and trans-institutional research program in infectious diseases of global importance. The unifying scientific theme of the COBRE is translational research at the interface of the pathogen and host. This COBRE represents a partnership between the Institute for Immunology and Informatics (I Cubed) at the University of Rhode Island's Providence campus, and the Center for International Health Research (CIHR) at Rhode Island Hospital. Both groups have established NIH-funded research programs in infectious diseases, immunology, and global health; their shared interests and close proximity in Providence present an ideal opportunity to create a synergistic research team. The Specific Aims of this COBRE are: 1. Establish an integrated research community to provide leadership in translational infectious diseases immunology research to the Rhode Island community. 2. Build infrastructure for immunology research through support for Research Cores in Statistics and Data Management, Cell Analysis and Sorting, and Luminex High-Throughput Analysis. 3. Recruit promising junior investigators and provide mentoring by established NIH-funded researchers. 4. Support a multidisciplinary research program led by junior investigators in translational infectious diseases immunology.

描述（由申请人提供）：传染病继续代表全球死亡和疾病的主要原因。我们应对新的和新兴的传染病挑战的战略是建立大量的传染病免疫学研究人员，并致力于协作和创新。这种毛cre的总体目标是“基于免疫疾病的免疫干预措施”，是为了促进发展全球重要性传染病的多学科和跨机构研究计划的发展。毛绒的统一科学主题是病原体和宿主界面的转化研究。该鞋底代表了罗德岛大学普罗维登斯校园的免疫学和信息学研究所（我立即）与罗德岛医院国际健康研究中心（CIHR）之间的合作伙伴关系。两组都建立了NIH资助的传染病，免疫学和全球健康方面的研究计划。他们的共同利益和在普罗维登斯的近距离邻近为建立协同研究团队提供了理想的机会。该毛绒的具体目的是： 1。建立一个综合的研究界，以向罗德岛社区提供转化传染病的领导能力。 2。通过支持统计和数据管理，细胞分析和分类的研究核心以及Luminex高通量分析来构建用于免疫学研究的基础架构。 3。招募有前途的初级研究人员，并由已建立的NIH资助的研究人员提供指导。 4.支持由转化传染病免疫学领域的初级研究人员领导的多学科研究计划。