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Development and Investigation of Assays For Cardiovascular Risk Assessment

Development and Investigation of Assays For Cardiovascular Risk Assessment
心血管风险评估检测方法的开发和研究
批准号：
8952837
负责人：
Alan Thomas Remaley
金额：
$0.0万
依托单位：
CLINICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8952837
关键词：
Apolipoproteins BBiological AssayCholesterolClinical InvestigatorCoronary ArteriosclerosisDevelopmentEffectivenessEnzymesGroupingInvestigationLipoproteinsMeasuresMeta-AnalysisMethodsPatientsPerformancePublishingRisk AssessmentRisk EstimateSignal TransductionTechniquesTestingbasecardiovascular risk factordiagnostic accuracyimprovedlipoprotein lipaseresponse

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英文摘要
In the past year, we evaluated and implemented a new method for measuring lipoprotein subtractions and size by NMR. This test is now available through CRIS for other clinical investigators to use. Using a variety of clustering techniques, are investigating the grouping of patients based on their lipoprotein profile, as measured by NMR, with cardiovascular risk. We are also investigating the change in the NMR signal in response to adding exogenous lipoprotein modifying enzymes, such as Lipoprotein Lipase, to determine if this provides additional information related to cardiovascular risk. We also participated in a recently published meta analysis comparing ApoB versus NMR for assessing cardiovascular risk.
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会议论文
Development Of New Assays For Lipoprotein Testing
  • 批准号：
    6675216
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    --
  • 负责人：
    Alan Thomas Remaley
  • 依托单位：
    CLINICAL CENTER
Development of recombinant Lecithin Cholesterol Acyltransferase as a therapeutic
Use Of Animal Models To Study Genes That Modulate Atherosclerosis
Development and Diagnostic Use of Rapid Immunoassays
  • 批准号：
    6227890
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    --
  • 负责人：
    Alan Thomas Remaley
  • 依托单位：
    CLINICAL CENTER
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