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Interplay between mutant p53 and PML; implications for tumourigenesis.

Interplay between mutant p53 and PML; implications for tumourigenesis.
突变体 p53 和 PML 之间的相互作用;
批准号:
nhmrc : 509197
负责人:
Prof Ygal Haupt
金额:
$32.26万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2011-12-31

项目摘要

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中文摘要
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英文摘要
The most important agent of the body for fighting cancer is the cellular protein p53. In more than 50% of all human cancers, it looses its anticancer properties through mutation. In an insidious manner this new mutant form then acts to promote cancer. To better treat cancer we need to understand how mutant p53 functions. We will study how it interacts with its molecular partners in cancer cells.
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A novel role for E6AP in cellular senescence
  • 批准号:
    nhmrc : 1026990
  • 项目类别:
    Project Grants
  • 资助金额:
    $34.16万
  • 财政年份:
    2012
  • 负责人:
    Prof Ygal Haupt
  • 依托单位:
Research Fellowship
  • 批准号:
    nhmrc : 628426
  • 项目类别:
    NHMRC Research Fellowships
  • 资助金额:
    $52.72万
  • 财政年份:
    2010
  • 负责人:
    Prof Ygal Haupt
  • 依托单位:
Regulation of PML by E6AP: implications for tumour development.
  • 批准号:
    nhmrc : 509196
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $35.86万
  • 财政年份:
    2008
  • 负责人:
    Prof Ygal Haupt
  • 依托单位:
海外基金