Improving Measurement and Treatment of Post-stroke Neglect

改善中风后忽视的测量和治疗

• 批准号: 9716401
• 负责人: Emily Grattan
• 金额: --
• 依托单位: RALPH H JOHNSON VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-06-01 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9716401
• 关键词: Achievement; Address; Affect; Attention; Award; Behavior assessment; Behavioral; Brain; Brain region; Caring; Clinical; Clinical Research; Clinical assessments; Communities; Cross-Over Studies; Development; Double-Blind Method; Effectiveness of Interventions; Environment; Exhibits; Failure; Foundational Skills; Funding; Future; Goals; Gold; Grant; Home environment; Impairment; Individual; Intention; Intervention; Intervention Studies; Knowledge; Laboratory Research; Lesion; Link; Measurement; Measures; Medical; Mentors; Mentorship; Methodology; Methods; Monitor; Motor; Movement; Occupational Therapist; Parietal; Patients; Positioning Attribute; Postdoctoral Fellow; Prevalence; Property; Randomized; Recovery; Rehabilitation Centers; Rehabilitation therapy; Research; Research Personnel; Research Training; Scientist; Self Care; Side; Solid; South Carolina; Spinal Cord; Stroke; Techniques; Testing; Training; Transcranial magnetic stimulation; Universities; Veterans; Work; Writing; attentional control; behavior test; career; clinical practice; compare effectiveness; design; disability; effective intervention; experience; hemiparesis; improved; improved outcome; inattention; innovation; kinematics; motor impairment; motor recovery; multidisciplinary; neglect; nervous system disorder; neural network; post stroke; post-doctoral training; rehabilitation research; research facility; response; skills; stroke rehabilitation; stroke survivor; theories; tool; trait; treatment planning

This CDA-2 candidate, Emily Grattan, is an occupational therapist and Post-Doctoral Scholar at the Medical University of South Carolina. Her intention is to become a VA RR&D investigator at the Ralph H. Johnson VAMC, Charleston SC. Dr. Grattan's short term goals are to develop advanced skills and knowledge in assessment of neglect, latent trait analyses, and non-invasive brain stimulation as well as enhance her grant writing skills and advance her professional development. Her long term goal is to become an independent investigator with a research focus on neglect rehabilitation and to improve the outcomes of individuals with neglect post stroke. Dr. Grattan has 5.5 years of clinical experience and has considerable research experience having worked on 10 different rehabilitation studies (9 stroke studies, 1 spinal cord study) during her doctoral and post-doctoral training. Her extensive clinical experience and strong doctoral and post-doctoral research training have provided a solid foundation of skills and knowledge. The next step towards becoming an independent VA research scientist requires advanced training and mentoring. To that end, Dr. Grattan has chosen a team of VA mentors with expertise in stroke rehabilitation research (Dr. Woodbury), latent trait analyses (Dr. Velozo), grant writing (Dr. Kautz), and non-invasive brain stimulation (Dr. George) who are uniquely qualified to advise the nominee. Dr. Grattan will conduct the proposed research in an ideal environment since she will have access to the Center for Rehabilitation Research in Neurological Disorders (CRRND), a state of the art research facility jointly funded by the VA and the University affiliate, which houses 4 rehabilitation research laboratories and includes a multidisciplinary staff of investigators and staff. The proposed project is designed to establish a valid assessment of post-stroke neglect that can immediately be used to advance the care of Veterans with stroke. Without precise and functionally-relevant measurement tools, rehabilitation therapists cannot accurately identify individuals with neglect, establish personalized rehabilitation treatment goals/plans, or monitor response to intervention. We will achieve our aims by examining the measurement properties of the items from three commonly used behavioral assessments (Catherine Bergego Scale, Behavioral Inattention Test behavioral subtests, and the Naturalistic Action Test) of neglect in individuals with stroke to define item sets that measure neglect and create forms that link the clinical assessment to a treatment plan personalized to the patient. We will also examine the preliminary effects of an innovative intervention (repetitive task-specific practice + transcranial direct current stimulation) for individuals with neglect. This project is significant because it will inform our understanding of the most effective methods to measure neglect, establish a tool to be utilized to assist in goal planning, and help to advise the development of future intervention studies.

这CDA-2候选人，艾米丽Gravity，是一个职业治疗师和博士后学者在 南卡罗来纳州医科大学。她的目标是成为一名VA RR&D调查员， 拉尔夫·H约翰逊VAMC，查尔斯顿南卡罗来纳州。 先进的技能和知识，在评估忽视，潜在的特点分析，和非侵入性 大脑刺激，以及提高她的赠款写作技巧，并提高她的专业 发展她的长期目标是成为一名专注于研究的独立调查员 忽视康复和改善个人的结果与忽视中风后。博士 Gravity拥有5.5年的临床经验，并具有相当丰富的研究经验， 在她的研究期间，她参与了10项不同的康复研究（9项中风研究，1项脊髓研究）。 博士和博士后培训。她丰富的临床经验和强大的博士和 博士后研究培训提供了坚实的技能和知识基础。下一 迈向成为一个独立的VA研究科学家需要先进的培训， 指导。为此，Grendy博士选择了一组具有中风专业知识的退伍军人事务部导师 康复研究（伍德伯里博士），潜在特质分析（Velozo博士），资助写作（考茨博士）， 和非侵入性脑刺激（乔治博士）谁是唯一合格的建议被提名人。 博士Gravity将在一个理想的环境中进行拟议的研究，因为她将有机会获得 神经疾病康复研究中心（CRRND）， 由VA和大学附属机构共同资助的研究设施，其中包括4个康复中心 研究实验室，包括一个多学科的调查人员和工作人员。 拟议的项目旨在建立一个有效的评估中风后忽视， 立即用于促进中风退伍军人的护理。没有精确的和 功能相关的测量工具，康复治疗师无法准确识别 个人忽视，建立个性化的康复治疗目标/计划，或监测 对干预的回应。我们将通过检查的测量性质来实现我们的目标 来自三种常用行为评估的项目（Catherine Bergego量表， 行为疏忽测试行为子测试，和自然主义行动测试）的忽视， 中风的个人定义项目集，测量忽视，并创建表格， 对患者个性化的治疗计划进行临床评估。我们亦会研究 创新干预的初步效果（重复性特定任务练习+经颅 直流电刺激）。这个项目意义重大，因为它将 让我们了解衡量忽视的最有效方法，建立一个工具， 用于协助目标规划，并帮助建议未来干预的发展 问题研究