Translational Neuroscience Core
Translational Neuroscience Core
批准号:
8846265
负责人:
Mary E Blue
金额:
$14.81万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AnimalsBiochemicalBiological AssayBrainClinicalClinical TrialsDevelopmental DisabilitiesDisease modelGoalsHistologyHumanImageIntellectual functioning disabilityLeadMental Retardation and Developmental Disabilities Research CentersMetabolicModelingResearch PersonnelSamplingScientistTrainingdevelopmental diseaseintellectual and developmental disabilityinterestpre-clinicaltranslational neuroscience
中文摘要
翻译神经科学核心(核心D)的目标是为神经科学家提供最好的专业知识。
分析导致智力和其他疾病的疾病的临床前(动物和人类)模型
发育障碍,以及相关临床样本的分析。另一个主要目标是
转化神经科学核心是促进基础发现转移到临床试验。实现
这些目标。核心D拥有在动物发育障碍建模方面具有专业知识的科学家,
专家谁可以进行分析,没有其他地方,可以解开
导致智力残疾的生化/代谢机制。在许多研究中,研究人员
利用翻译神经科学核心感兴趣的是可视化对大脑的影响。的一个主要
核心D的职能是提供培训和组织学和临床前成像设施。
另一个主要功能是提供一组针对代谢物和分子的高度专业化的测定
与智力和发育障碍相关。
英文摘要
The objective of the Translational Neuroscience Core (Core D) is to provide the best expertise possible to the
analysis of preclinical (animal and human) models of disorders that lead to intellectual and other
developmental disabilities, and to the analysis of relevant clinical samples. Another primary goal of this
Translational Neuroscience Core is to facilitate the transfer of basic discoveries to clinical trials. To achieve
these objectives. Core D has scientists with expertise in modeling developmental disorders in animals and
experts who can perform assays that are not available elsewhere and that can unravel the
biochemical/metabolic mechanisms that cause intellectual disability. For many of the studies, investigators
utilizing the Translational Neuroscience Core are interested in visualizing effects on the brain. One of the major
functions of Core D is to provide training and access to the Histology and Preclinical Imaging Facilities.
Another major function is to provide a group of highly specialized assays that target metabolites and molecules
of relevance to intellectual and developmental disorders.
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科研奖励(0)
会议论文
Targeted Therapies for Rett Syndrome
-
批准号:9811146
-
项目类别:
-
资助金额:$43.48万
-
财政年份:2019
-
负责人:Mary E Blue
-
依托单位:
Targeted Therapies for Rett Syndrome
-
批准号:9916821
-
项目类别:
-
资助金额:$40.59万
-
财政年份:2019
-
负责人:Mary E Blue
-
依托单位:
Dendrimer therapies for treatment of Rett Syndrome
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批准号:9334327
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项目类别:
-
资助金额:$20.39万
-
财政年份:2016
-
负责人:Mary E Blue
-
依托单位:
Dendrimer therapies for treatment of Rett Syndrome
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批准号:9235088
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项目类别:
-
资助金额:$26.0万
-
财政年份:2016
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负责人:Mary E Blue
-
依托单位:
Carl Zeiss AxioImager Z1 Research Microscope
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批准号:7794149
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项目类别:
-
资助金额:$13.85万
-
财政年份:2010
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负责人:Mary E Blue
-
依托单位:
A Mouse Model for Autism: Postnatal Serotonergic Effects
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批准号:7551725
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项目类别:
-
资助金额:$25.79万
-
财政年份:2007
-
负责人:Mary E Blue
-
依托单位:
A MOUSE MODEL FOR AUTISM: POSTNATAL SEROTONERGIC EFFECTS
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批准号:6670962
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项目类别:
-
资助金额:$26.31万
-
财政年份:2003
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负责人:Mary E Blue
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依托单位:
EXCITATORY AMINO ACIDS AND CORTEX DEVELOPMENT
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批准号:2267416
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项目类别:
-
资助金额:$10.33万
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财政年份:1992
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负责人:Mary E Blue
-
依托单位:
EXCITATORY AMINO ACIDS AND CORTEX DEVELOPMENT
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批准号:2267417
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项目类别:
-
资助金额:$10.75万
-
财政年份:1992
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负责人:Mary E Blue
-
依托单位:
ROLE OF EXCITATORY AMINO ACIDS IN CORTEX DEVELOPMENT
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批准号:3478217
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项目类别:
-
资助金额:$9.43万
-
财政年份:1992
-
负责人:Mary E Blue
-
依托单位:
EXCITATORY AMINO ACIDS AND CORTEX DEVELOPMENT
-
批准号:2267415
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项目类别:
-
资助金额:$9.81万
-
财政年份:1992
-
负责人:Mary E Blue
-
依托单位:
ROLE OF EXCITATORY AMINO ACIDS IN CORTEX DEVELOPMENT
-
批准号:3478216
-
项目类别:
-
资助金额:$9.07万
-
财政年份:1992
-
负责人:Mary E Blue
-
依托单位:
NEOCORTICAL PLASTICITY FOLLOWING NEUROTOXIN LESIONS
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批准号:3053618
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项目类别:
-
资助金额:$2.6万
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财政年份:1985
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负责人:Mary E Blue
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依托单位:
Translational Neuroscience Core
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批准号:9924009
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项目类别:
-
资助金额:$14.29万
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财政年份:--
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负责人:Mary E Blue
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依托单位:
A MOUSE MODEL FOR AUTISM: POSTNATAL SEROTONERGIC EFFECTS
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批准号:7551721
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项目类别:
-
资助金额:$27.86万
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财政年份:--
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负责人:Mary E Blue
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依托单位:
A MOUSE MODEL FOR AUTISM: POSTNATAL SEROTONERGIC EFFECTS
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批准号:7551713
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项目类别:
-
资助金额:$28.13万
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财政年份:--
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负责人:Mary E Blue
-
依托单位:
A MOUSE MODEL FOR AUTISM: POSTNATAL SEROTONERGIC EFFECTS
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批准号:7551717
-
项目类别:
-
资助金额:$27.99万
-
财政年份:--
-
负责人:Mary E Blue
-
依托单位:
海外基金