Comprehensive Assessment of Retinal Vasculature (CARV)

摘要 电视治疗项目近年来有所扩大，主要是为了筛查糖尿病 视网膜病变。对视网膜血管系统的准确和一致的评估，这通常是 心血管疾病造成的损害，将在以下方面推进电视筛查 健壮性和成本。不幸的是，评估视网膜血管系统的变化并量化 事实证明，视网膜图像的异常更加困难。报道了半自动方法 以减少评分员的可变性，但它们很耗时，需要广泛的读者 相互作用，从而限制了远程筛查计划的整体有效性。 VisionQuest Biomedical及其合作者南得克萨斯州视网膜研究所(RIST)将 演示用于全面评估视网膜血管(CAV)的软件工具以帮助 读者在血管异常的定量描述和鉴定中的作用 具有潜在威胁视力或生命危险情况的特征的图像。 CAV将为读者提供实时的动脉与静脉比率(AVR)测量，一个公认的 对确定未来中风或高血压事件风险的临床价值以及 与分枝模式和曲折相关的测量。它还将包括 针对铜线和银线、房室划痕和栓子等特征的检测算法。我们的 目的是为视网膜分级提供帮助，以检测和量化常见的视网膜 血管异常与视网膜专家的金标准高度一致。在这 第一阶段，我们还将实施临床接受的血管系统定量测量。 参数。 CAV可以集成到糖尿病患者的远程系统中，它将允许评分员 始终如一地识别高血压视网膜病变和心血管相关疾病的迹象， 医疗服务提供者充分发挥远程筛查的潜力。

Summary Teleretinal programs have expanded in recent years, primarily to screen for diabetic retinopathy. Accurate and consistent assessment of the retinal vasculature, which often sustains damage as a result of cardiovascular disease, would advance teleretinal screening in terms of robustness and cost. Unfortunately, assessing changes to the retinal vasculature and quantifying abnormalities in retinal images has proven more difficult. Semi-automatic methods are reported to reduce grader variability, but they are time-consuming, requiring extensive reader interaction, thus limiting the overall effectiveness of a teleretinal screening program. VisionQuest Biomedical and its collaborator, the Retina Institute of South Texas (RIST), will demonstrate a software tool for comprehensive assessment of retinal vasculature (CARV) to aid readers in the quantitative characterization of vascular abnormalities and identification of those images with features indicative of potential sight-threatening or life-threatening conditions. CARV will provide the reader real-time artery to vein ratio (AVR) measurements, an accepted clinical value for determining risk of future stroke or hypertensive events, as well as measurements associated with branching patterns and tortuosity. It will also incorporate detection algorithms for features such as copper and silver wiring, AV nicking, and emboli. Our goal is to provide an aid to the retinal grader for detecting and quantifying common retinal vessel abnormalities with high agreement with the gold standard, a retinal specialist. In this Phase I we will also implement clinically accepted quantitative measurements for vasculature parameters. CARV, which can be integrated into a teleretinal system for diabetics, will allow graders to consistently identify signs of hypertensive retinopathy and CVD-related conditions and providers to exploit the full potential of teleretinal screening.