Evaluation of Dengue Epidemiology, Outcomes and Prevention in Sentinel Surveillan

哨点监测中登革热流行病学、结果和预防的评估

• 批准号: 8721198
• 负责人: Hector F Gorbea
• 金额: $ 16.67万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-01 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8721198
• 关键词: Evaluation; Dengue; Epidemiology; Outcomes; Prevention

DESCRIPTION (provided by applicant): The Puerto Rico Active Dengue Surveillance (PRADS) is a research project that aims to develop an infrastructure for a hospital-based active dengue surveillance system that will serve as a model and as a platform to study the epidemiology of dengue in Puerto Rico (PR). Dengue is endemic in PR with increasing number of cases and severity of disease. It has been difficult to control. The objectives of the project include studying the age-specific incidence of symptomatic dengue from infants to adults, estimating the clinical burden of disease, describing the clinical presentation and outcomes of pediatrics and adult patients diagnosed with dengue, and determining the management practices associated with poor outcomes. The surveillance activities for the project will be located at the University of Puerto Rico School of Patients and the University Pediatric Hospital; both are referral tertiary care hospitals located at the Medical Center in San Juan, and the UPR Hospital a secondary care hospital located in Carolina. Case finding will start with acute febrile patients in all age groups from infants to adults. Patients with dengue fever will be followed through the disease. The surveillance protocol will include medical history, physical examination, and laboratory testing including dengue diagnostic tests. Electronic data collection will be done using the RedCAP system for collecting, storing, and disseminating project- specific research data.

描述（由申请方提供）：波多黎各登革热主动监测（PRADS）是一个研究项目，旨在为基于医院的登革热主动监测系统开发基础设施，该系统将作为研究波多黎各（PR）登革热流行病学的模型和平台。登革热是PR的地方病，病例数量和疾病严重程度不断增加。很难控制。该项目的目标包括研究从婴儿到成人的症状性登革热的年龄特异性发病率，估计疾病的临床负担，描述诊断为登革热的儿科和成人患者的临床表现和结局，并确定与不良结局相关的管理实践。该项目的监测活动将在波多黎各大学患者学校和大学儿科医院进行;这两所医院都是位于圣胡安医疗中心的三级转诊医院，UPR医院是位于卡罗莱纳的二级医院。病例发现将从所有年龄组的急性发热患者开始，从婴儿到成人。登革热患者将在整个疾病期间接受随访。监测方案将包括病史、体检和实验室检测，包括登革热诊断检测。电子数据收集将使用RedCAP系统进行，用于收集、存储和传播特定项目的研究数据。