Establishing a prioritized research agenda for nontuberculous mycobacterial infec

描述（由申请人提供）：本申请寻求部分支持（R13），用于一个研讨会，旨在定义和优先考虑由非结核分枝杆菌（NTM）感染引起的疾病的研究议程。拟议的为期2天的研讨会由美国胸科学会（ATS）组织，并将在计划于2014年5月在加利福尼亚州圣地亚哥举行的年度ATS会议之前举行。NTM代表了150多个不同的物种，在许多地区，这些环境生物体引起的未感染HIV的个体的感染率正在增加。不幸的是，由于缺乏研究，我们对NTM感染的理解受到了极大的阻碍。ATS与美国传染病学会合作，发布了NTM感染管理指南。然而，这些建议往往不是基于证据的，正如2007年发布的先前指南所审查的那样，仍然存在许多未回答的问题。ATS希望召开一次研讨会，以确定和优先考虑NTM研究议程，这将改善该领域的重点，并希望提供资金的机会。我们提出以下目标：1.在2014年制定并举办一个研讨会，以确定NTM感染的优先研究议程; 2.在安非他明类兴奋剂杂志上发表讲习班的会议记录和建议;通过“安非他明类兴奋剂”网站（安非他明类兴奋剂主办的一个播客）和通过向全国30多个国家培训方式支助团体分发文件，进一步传播讲习班的结论。具体目标将通过汇集大约60名对NTM感染感兴趣和具有专业知识的临床医生、科学家和患者代表以及该研究领域以外的科学家来实现。

DESCRIPTION (provided by applicant): This application seeks partial support (R13) for a workshop aimed at defining and prioritizing a research agenda for disease caused by non-tuberculosis mycobacterial (NTM) infections. The proposed 2-day workshop is being organized by the American Thoracic Society (ATS) and will be held prior to the annual ATS conference planned for May 2014 in San Diego, CA. NTM represent over 150 different species and the incidence of infections in HIV uninfected individuals caused by these environmental organisms is increasing in many areas. Unfortunately, our understanding of NTM infections is greatly hampered by a lack of research. The ATS, in collaboration with the Infectious Diseases Society of America, has published guidelines on the management of NTM infections. However, the recommendations are often not evidence based and as reviewed in the previous guidelines published in 2007, there remain many unanswered questions. The ATS would like to convene a workshop to define and prioritize a NTM research agenda that will improve the field's focus and hopefully funding opportunities. We propose the following aims: 1. Develop and hold a workshop in 2014 to define a prioritized research agenda for NTM infections; 2. Publish the proceedings and recommendations of the workshop in an ATS journal; 3. Further disseminate the findings of the workshop through the ATS website, a podcast hosted by ATS, and through dissemination of the document to the over 30 NTM support groups across the country. The specific aims will be accomplished by bringing together approximately 60 clinicians, scientists and patient representatives with interest and expertise in NTM infections as well as scientists outside of this area of investigation.