Administrative and Biostatistics Core

以下是俄亥俄州立大学(OSU)核心C的目标：(1)培养频繁和 参与工作各方之间的相关沟通通过提供基本的 行政事务；(2)在以下方面提供生物统计支助：(A)协作设计 确保最终结果的实验；(B)公害变量的建模和敏感性分析 实验数据；(C)发现、训练和确认高维数据的综合分析 数据；(D)探索性分析和直观展示数据，以澄清结论和发现线索；(E) 调查独特的统计方法--直接处理困难数据或设计问题；和(F) 协助提供储存项目生物结果电子版的数据库； (3)定期(每年三次)为高级调查人员及其 实验室成员；(4)聘请外部审查委员会，并组织该委员会的年会 小组和奥斯陆联盟内部咨询委员会。外部咨询委员会成员应 审查所有实验结果，帮助确定调查的优先顺序，审查协作的协调情况，以及 评估研究中出现的概念；(5)组织一个内部咨询委员会， 俄亥俄州立大学的专家小组应就计划的有效性和实验进展、研究提供建议 指导、技术方法、统计评价和行政效力；(7)提供 为调查员提供与项目有关的通信的出版服务，其中包括 手稿、摘要和其他出版物的编写，包括写作的总体进展 整个计划项目的年度报告，提交给资助机构NCL/NIH；(8) 提供全面的财政审查、会计和预算分析；(8)提供一个数据库，其中包括 项目记录电子版；(9)维护与本项目相关的网站； 作为项目项目的主要联系人，与新的制药公司合作伙伴卫材， Inc.和NCI计划官员。 相关性(请参阅说明)： 该方案项目核心的主要目的是提供基本的整体行政管理 为该方案项目的所有其他组成部分提供功能和生物统计学及其他统计支持。 通过这种方式，将有助于以平稳、精简的方式开展计划中的工作。 项目/绩效站点(S)(如果需要额外空间，请使用项目/

The following are the objectives of Core C at The Ohio State University (OSU): (1) To foster frequent and relevant communications between all parties involved in the work through the provision of basic administrative services; (2) To provide biostatistics support in terms of (a) collaboration on design of experiments to ensure conclusive results; (b) modeling of nuisance variables and sensitivity analyses of experimental data; (c) integration of analyses for discovery, training, and validation of high dimensional data; (d) exploratory analyses and visual displays of data that clarify conclusions and uncover leads; (e) investigation of unique statistical methods to-directly address difficult data or design problems; and (f) assistance with the provision of a database housing an electronic version of the project biological results; (3) To organize regular (three times annually) technical meetings for the senior investigators and their laboratory members; (4) To recruit an External Review Committee and organize an annual meeting of this group and the OSU Internal Advisory Committee. The members of External Advisory Committee shall review all experimental findings, help prioritize investigations, review the coordination of collaborations, and evaluate concepts that emerge from the studies; (5) To organize an Internal Advisory Committee where a panel of experts at OSU shall advise on the program effectiveness and experimental progress, research directions, technical approaches, statistical evaluation, and administrative effectiveness; (7) To provide publication services to the investigators for project related communications where this includes the preparation of manuscripts, abstracts, and other publications, including the writing of an overall progress report annually for the entire program project, to be submitted to the funding agency, NCl/NIH; (8) To provide overall fiscal review, accounting, and budget analyses; (8) To provide a database housing an electronic version pf the project records; (9) To maintain a website in relation to this program project; (10 To serve as primary contact for the program project with a new pharmaceutical company partner, Eisai, Inc. and the NCI Program Officer. RELEVANCE (See instructions): The primary purposes of this core of the program project are to provide basic overall administrative functions and biostatististical and other statistical support to all other components of this program project. In this manner a smooth, streamlined approach to the work planned will be facilitated. PROJECT/PERFORIWANCE SITE(S) (if additional space is needed, use Project/