Core A: Administrative and Biostatistics Core

核心 A：行政和生物统计学核心

• 批准号: 10621886
• 负责人: Alan Douglas Kinghorn
• 金额: $ 17.35万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10621886
• 关键词: Address; Advisory Committees; Antineoplastic Agents; Authorship; Biological; Biological Assay; Biometry; Biostatistics Core; Budgets; Chemicals; Chicago; Collaborations; Cyanobacterium; Data; Data Display; Databases; Dependence; Development; Disputes; Drug Kinetics; Effectiveness; Electronics; Ensure; Evaluation; Experimental Designs; Fostering; Goals; Grant; Housing; Illinois; Industrialization; Information Dissemination; Institution; Investigation; Laboratories; Leadership; Lichen - organism; Malignant Neoplasms; Methods; Modeling; Molds; North Carolina; Occupational activity of managing finances; Ohio; Persons; Pharmaceutical Chemistry; Pharmacologic Substance; Plants; Program Effectiveness; Program Efficiency; Program Research Project Grants; Provider; Research; Research Personnel; Research Project Grants; Resource Allocation; Scientist; Services; Statistical Methods; Structure; Teleconferences; Telephone; Training; Universities; Validation; Visual; Work; chemotherapeutic agent; computerized data processing; design; experimental analysis; fungus; meetings; member; multidimensional data; novel; operation; preservation; programs; symposium; tumor; videoconference

The overall goals of the Administrative and Biostatistics Core (Core A) are to 1) continue to provide a structure to facilitate effective interactions toward the accomplishment of the aims of this Program Project and specifically to foster and promote the goals of the Program and each component (cores and projects) by providing scientific direction, administrative and budgetary support, oversight, integration of program activities and the industrial partner, and ensuring operational efficiency; and 2) to continue to provide biostatistics and other statistical support for the P01. The following are the objectives of Core A: 1) provide research direction by setting the research agenda focused on the discovery of novel chemicals from selected tropical rainforest plants, as well as lichens, cyanobacteria and filamentous fungi, for development as cancer chemotherapeutic agents, particularly for tumors not cured by present treatment methods. 2) Ensure operational efficiency for Program components by providing centralized grant administration, information dissemination, budget data processing, and exchange of information and services. 3) Promote integration of the Research Projects and Cores to promote interaction among the three primary universities represented by the investigators, and relevant external entities and 4) provide biostatistics support for the three Projects and the two Cores of the P01 Program. Core A will continue to ensure that all components of the Program work seamlessly together to accomplish the overall and specific project goals of the P01 Program.

行政和生物统计核心(核心A)的总体目标是：1)继续提供结构 促进有效互动，以实现本计划项目的目标，具体而言 通过提供科学的方法，促进和促进方案和每个组成部分(核心和项目)的目标 指导、行政和预算支助、监督、方案活动和工业 合作伙伴，确保业务效率；和2)继续提供生物统计和其他统计 对P01的支持。以下是核心A的目标：1)通过设定 研究议程的重点是从选定的热带雨林植物中发现新的化学品，以及 地衣、蓝藻和丝状真菌，用于开发癌症化疗药物，特别是 对于目前治疗方法不能治愈的肿瘤。2)确保程序组件的运行效率 通过提供集中的赠款管理、信息传播、预算数据处理和交换 信息和服务。3)促进研究项目和核心的整合，促进互动 在调查员代表的三所初级大学中，以及相关的外部实体和4个) 为P01计划的三个项目和两个核心提供生物统计支持。核心A将继续 确保计划的所有组成部分无缝协作，以完成总体和具体的 P01计划的项目目标。