Investigating cortical plasticity and connectivity in people with chronic low back pain and controls using combined TMS_EEG

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Little is known about the factors that predispose the development of chronic low back pain or what changes underpin effective treatment. Brain changes, thought to reflect adaptive processes are associated with chronic pain, but the extent of their contribution to CLBP is unknown. By measuring the adaptability of brain changes in people with CLBP I will determine if they differ from healthy controls in a way that predisposes them to develop chronic pain and is related to treatment response.