Software Development & Core Facilities

软件开发

• 批准号: 8796477
• 负责人: Alessandro Vespignani
• 金额: $ 18.1万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8796477
• 关键词: Academia; Adoption; Algorithms; Architecture; Area; Client; Cloud Computing; Communicable Diseases; Communities; Computer Simulation; Computer software; Core Facility; Data; Data Analyses; Development; Environment; Feedback; Fostering; Goals; Grant; Hybrids; Individual; Influenza; Manuals; Methodology; Modeling; Plug-in; Public Health; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Resolution; Simulate; Source Code; Sum; Testing; Training; Translating; Update; Work; base; computer infrastructure; computerized tools; data exchange; design; experience; graphical user interface; infectious disease model; multi-scale modeling; novel; open source; programs; public health research; repository; simulation; software development; software repository; statistics; tool; web site

The overall goal of the software development and core facilities section is to make the new methodologies, algorithms, and models developed in the MIDAS Center's research projects more accessible to both the research and public health communities. To do so, we will integrate some of the independently developed tools to create a coherent computational infrastructure that is more than the sum of its methodological parts. In particular, we propose to develop and to maintain a suite of computational tools for infectious disease modeling and analysis centered around a multi-scale modeling computational platform (MCP), optimized for cloud deployment. The major aims of the software developments are: i) Develop an MCP capable of integrating large scale stochastic modeling approaches working at different scales of resolution. We will start by creating a multiscale hybrid model based on combining the global individual-based metapopulation model GLEAM with the US scale agent-based influenza model FluTE. The MCP architecture will be designed around the existing GLEAMviz client-server architecture. It will be expanded with the development of Application Programming Interfaces (APIs) for the plug-in of models developed by the MIDAS research community. The MCP will consist of computationally intensive tools, so we plan to design and to deploy a cloud computing environment with elastic capabilities, ii) Develop new features and graphical user interfaces (GUIs) for statistical tools developed in the context of the research activities of the Center such as extensions of pomp, TranStat, among others. We will develop integrated workflows aimed at allowing those programs to exchange data and parameter estimates with the MCP in an automated way. iii) Develop a website that will act as a sharing repository for the software developed in this MIDAS Center, with training materials, manuals, and workflow examples. We aim to provide the best accessibility and to foster adoption of the developed software by MIDAS, the research community, and public health agencies by using best practices and public repositories

软件开发和核心设施部分的总体目标是使MIDAS中心研究项目中开发的新方法、算法和模型更容易为研究界和公共卫生界所用。为此，我们将集成一些独立开发的工具，以创建一个连贯的计算基础设施，而不仅仅是其方法部分的总和。特别是，我们建议开发和维护一套以多尺度建模计算平台（MCP）为中心的传染病建模和分析计算工具，并针对云部署进行优化。软件开发的主要目标是：