NRG Oncology NCORP Research Base

NRG肿瘤学NCORP研究基地

• 批准号: 8790796
• 负责人: Deborah Watkins Bruner
• 金额: $ 1118.54万
• 依托单位: NRG ONCOLOGY FOUNDATION, INC.
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8790796
• 关键词: Address; Adjuvant; Advocate; Affect; Aftercare; American; American Society of Clinical Oncology; Area; Biological Markers; Breast; Cancer Center; Cancer Control; Cancer Control Research; Cancer Survivor; Clinical Research Associate; Clinical Trials; Clinical Trials Design; Clinical Trials Network; Collaborations; Collection; Commit; Communities; Community Clinical Oncology Program; Community Physician; Correlative Study; Credentialing; Data Analyses; Data Collection; Diagnostic Procedure; Disease; Disorder by Site; Early Diagnosis; Eligibility Determination; Ensure; Funding; Goals; Gynecologic Oncology; Gynecologic Oncology Group; Health Services Accessibility; Hospice Care; Image; Incidence; Information Technology; Institute of Medicine (U.S.); Internal Medicine; Intervention; Intervention Trial; Lead; Leadership; Malignant Neoplasms; Measures; Minority; Molecular Genetics; Monitor; Morbidity - disease rate; National Cancer Institute; Operative Surgical Procedures; Outcome; Palliative Care; Patient Outcomes Assessments; Patients; Principal Investigator; Publishing; Quality Control; Quality of life; Radiation Oncology; Radiation Therapy Oncology Group; Radiation therapy; Reporting; Research; Research Infrastructure; Research Personnel; Resources; Screening for cancer; Security; Site; Societies; Solid Neoplasm; Symptoms; System; Techniques; Testing; Therapeutic Clinical Trial; Therapy Clinical Trials; Training and Education; Translational Research; Treatment-Related Cancer; Underrepresented Minority; Woman; Women' s Health; Work; anticancer research; base; cancer care; cancer diagnosis; cancer prevention; care delivery; clinical decision-making; data integrity; data management; design; experience; improved; innovation; meetings; member; multidisciplinary; oncology; programs; public health relevance; quality assurance; response; screening; survivorship; therapy design; treatment trial

DESCRIPTION (provided by applicant): The objective of this proposal is to establish and maintain the NCORP (National Cancer Institute Community Oncology Research Program) for the NRG Oncology research base. The NRG NCORP is the result of aligning the legacy CCOPs (Community Clinical Oncology Programs) from three NCI Cancer Cooperative Groups: NSABP, RTOG and GOG. These groups together have over almost 100 years of combined experience serving as CCOP Research Bases. NRG NCORP, comprised of a multi-disciplinary team of investigators and patient advocates, is poised to carry out the objectives of: 1) designing and conducting cancer prevention, control and screening clinical trials; 2) designing and embedding patient reported outcomes in therapeutic trials 3) designing and conducting cancer care delivery research; 4) enhancing community access to treatment and imaging trials conducted under the National Clinical Trials Network (NCTN) and 5) integrating disparity research questions into clinical trials and cancer care delivery research. To allow NRG NCORP to meet these goals, the group will: participate fully in NRG Oncology leadership and will determine the scientific direction and prioritization of the NRG NCORP activities and resources and oversee the translational research, clinical trial activities, and correlative studies related to the aims of NG NCORP. With the NRG Statistical and Data Management Center, this team will provide efficient, methodologically up-to-date trial design, monitoring, reporting, and analysis; build an infrastructure to support our cancer care delivery research agenda; provide comprehensive data management quality control and quality assurance programs to ensure high data integrity and timely data for analysis; leverage cutting edge information technology emphasizing security, timeliness, and efficiency of data collection and management; providing RT credentialing and quality assurance; and provide education and training for institutional Clinical Research Associates, Study Chairs, local Principal Investigators and others involved in the NRG NCORP research agenda. Further, to accomplish these aims NRG NCORP will engage fully with NCI-designated NCORP community physicians and patient advocates as well as the NCI and other NCl-sponsored entities (cooperative groups, cancer centers, SPOREs) to collaborate across the NCTN to improve cancer care and quality of life for patients affected by cancer.

描述（由申请人提供）：该提案的目的是为NRG肿瘤研究基础建立和维护NCORP（国家癌症研究所社区肿瘤研究计划）。 NRG NCORP是来自三个NCI癌症合作组的传统CCOP（社区临床肿瘤学计划）的结果：NSABP，RTOG和GOG。这些群体共同拥有将近100年的合并经验作为CCOP研究基础。 NRG NCORP由一个由研究人员和患者倡导者组成的多学科团队组成，有望实现：1）设计和进行预防，控制和筛查临床试验； 2）设计和嵌入患者报告的治疗试验结果3）设计和进行癌症护理递送研究； 4）增强在国家临床试验网络（NCTN）和5）将差异研究问题整合到临床试验和癌症护理提供研究中进行的社区获得治疗和成像试验。为了允许NRG NCORP实现这些目标，该小组将：完全参与NRG肿瘤学领导力，并将确定NRG NCORP活动和资源的科学方向和优先级，并监督与NG NCORP的目标相关的转化研究，临床试验活动以及相关研究。借助NRG统计和数据管理中心，该团队将提供有效的，方法论上最新的试验设计，监视，报告和分析；建立一个基础设施来支持我们的癌症护理提供研究议程；提供全面的数据管理质量控制和质量保证计划，以确保高数据完整性和及时的数据进行分析；利用尖端信息技术强调数据收集和管理的安全性，及时性和效率；提供RT证书和质量保证；并为机构临床研究协会，研究主席，当地主要研究人员以及参与NRG NCORP研究议程的其他人提供教育和培训。此外，为了实现这些目标，NRG NCORP将与NCI指定的NCORP社区医生和患者倡导者以及NCI和其他NCL赞助的实体（合作团体，癌症中心，孢子）合作，以改善癌症患者的癌症护理和生活质量。