Data Coordinating Center for the NHLBI Asthma Network (AsthmaNet)

NHLBI 哮喘网络数据协调中心 (AsthmaNet)

• 批准号: 8694083
• 负责人: David T. Mauger
• 金额: $ 1444.95万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8694083
• 关键词: Acute Renal Failure with Renal Papillary Necrosis; Address; Adult; Advanced Development; Affect; Allergic; Archives; Asthma; Behavior Therapy; Birth; Case Report Form; Certification; Child; Child health care; Childhood; Chronic Disease; Clinical; Clinical Management; Clinical Research; Clinical Trials; Collaborations; Common Data Element; Communication; Communities; Community Health; Data Collection; Data Coordinating Center; Data Quality; Databases; Development; Diet; Disease; Enrollment; Exercise; Family; Fetus; Funding; Health Sciences; Home environment; Individual; Infant; Leadership; Longevity; Lung; Manuals; Medical; Medicine; Monitor; National Heart, Lung, and Blood Institute; National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; Observational Study; Office of Administrative Management; Outcome; Parents; Pennsylvania; Performance; Perinatal; Persons; Physiological; Positioning Attribute; Pregnancy; Pregnant Women; Procedures; Protocols documentation; Public Health; Qualifying; Reporting; Research; Research Design; Research Infrastructure; Research Personnel; Resource Sharing; Resources; Role; Sample Size; Staging; Standardization; Statistical Data Interpretation; Strategic Planning; System; Telephone; Training; Translational Research; United States National Institutes of Health; Universities; Wheezing; Work; Writing; aged; clinical care; college; design; dissemination research; environmental intervention; experience; family influence; flexibility; improved; meetings; novel; novel strategies; operation; protocol development; randomized trial; symposium

DESCRIPTION (provided by applicant): Asthma affects more than 22 million persons and it is one ofthe most common chronic diseases of childhood. The NHLBI is establishing AsthmaNet, a clinical research network that will develop and conduct multiple clinical trials to address important clinical management questions and new approaches to treating asthma across the lifetime. The NHLBI's strategic plan for clinical research networks includes maintaining a focus on improving clinical care; allowing flexibility in research designed to advance the development of novel therapies and translational research; promoting scientific exchange, use of resources and standardization across networks; and facilitating rapid dissemination of research findings to the medical community. AsthmaNet will include multiple Clinical Centers (CCs) and one Data Coordinating Center (DCC). The Department of Public Health Sciences (DPHS) at The Pennsylvania State University College of Medicine proposes to serve as the DCC for AsthmaNet. The DCC will have a central role in all stages of AsthmaNet studies from design and development to implementation, analysis, and dissemination of results. Specifically, DPHS will; (1) provide statistical and data analysis expertise for all studies, including statistical design and sample size estimation; (2) establish and manage the study databases; (3) establish and manage a communication systems; (4) provide scientific coordination for the CCs that includes collaborating with the AsthmaNet investigators on protocol development and implementation, formatting data collection forms for each protocol, preparing and leading training sessions, establishing certification criteria for AsthmaNet procedures, and writing the manuals of operations; (5) monitor and evaluate protocol execution and quality of data and provide reports to NHLBI; (6) provide project management and administrative support, including arranging meetings and telephone conference for all AsthmaNet related committees; (7) establish, maintain, and provide oversight to subcontracts; (8) collaborate with the NHLBI and other networks involved in pulmonary research to standardize common data elements and practices to increase operational efficiency; (9) manage NHLBI protocol funds and distribute them to the CCs; and (10) prepare public-use files for archiving and sharing study results, disseminating research findings, and sharing resources such as study manuals and case-report forms.

描述（由申请人提供）：