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中文摘要
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描述(申请人提供):这是一个申请部分支持信号的黏附受体戈登研究会议和相关的戈登研究研讨会在2014年。这将是本次高级会议的第8次会议,也是GRS的第二次会议,将于6月21日至27日在密歇根州刘易斯顿的贝茨学院举行。从历史上看,该会议提供了一个独特的论坛,将一个由早期职业和资深科学家组成的国际小组聚集在一起,他们对粘连信号的机制及其与发育和疾病的相关性有共同的兴趣,即将举行的会议也不例外。建立了合作关系,招募了新的科学家到这个领域,关于黏附信号的重大发现经常是第一次在这次会议上报道。会议的具体目标是:“传播有关黏附信号的新数据和新概念。”促进基础研究小组、临床研究小组以及制药和生物技术公司之间的互动和合作。“让研究人员熟悉新的实验方法和新兴技术。”为讨论新的假设和方法提供非正式的氛围.为初级和高级调查人员提供一种合作、互动的氛围。至 增加参加会议的学生和研究员的数量和多样性,特别注重妇女、少数群体和残疾人。2014年的计划将重点放在所有研究最活跃的主题领域中关于黏附信号的新的未发表的发现。重要的是,会议保留了传统计划的几个方面,并引入了新的和新兴的领域,以增强人们的兴趣,增加会议的申请者,确保整个星期的热情,并促进该领域的重大进步。重要的是,每堂课都会有一到两个来自研究生、博士后研究助理或早期职业研究人员的演讲。这些演讲者将从提交的摘要中挑选出来,以创造讨论最新发现的机会,并将令人兴奋的海报作为口头演示。此外,将从与主要会议同时举行的全球代表大会的竞争中选出两名发言者。与去年会议相关的新主题包括黏附信号的空间控制、细胞利基和组织结构、细胞分裂和极性的黏附控制以及肿瘤细胞侵袭和黏附信号治疗。还包括重要主题的最新进展,如张力感应和信号,细胞骨架调节,迁移机制,以及发育过程中黏附信号的体内模型。总体而言,这次国际会议将展示黏附信号研究领域的主要进展,并将一如既往地成为该领域的开创性会议。
英文摘要
DESCRIPTION (provided by applicant): This is an application for partial support of the Signaling by Adhesion Receptors Gordon Research Conference and the associated Gordon Research Seminar in 2014. It will be the 8th meeting of this premier conference and the second meeting of the GRS, and will be held at Bates College, Lewiston, ME from June 21-27. The conference has historically provided a unique forum to bring together an international group of early career and senior scientists with a common interest in the mechanisms of adhesion signaling and their relevance to development and disease, and this upcoming conference is no exception. Collaborations are established, new scientists are recruited to the field, and major discoveries about adhesion signaling are often reported for the first time at this conference. Specific Aims for the conference: " To disseminate new data and concepts about adhesion signaling. " To promote interactions and collaborations among basic research groups, clinical research groups, and pharmaceutical and biotechnology companies. " To familiarize investigators with new experimental approaches and emerging technologies. " To provide and informal atmosphere for discussion of new hypotheses and approaches. " To provide a collegial, interactive atmosphere in which both junior and senior investigators may interact. " To increase the number and diversity of students and fellows attending the conference, with a particular focus on women, minorities and persons with disabilities. The 2014 program will focus on new unpublished findings on adhesion signaling in all of the most actively researched topic areas. Importantly, few aspects of the traditional program in the conference have been retained, and new and emerging areas introduced to bolster interest, increase applicants for the conference, ensure enthusiasm throughout the week, and promote major advancements in the field. Importantly, each session will feature one or two talks from graduate students, postdoctoral research associates or early career investigators. These speakers will be selected from submitted abstracts to create opportunities for discussion of late-breaking discoveries and incorporate exciting posters as oral presentations. In addition, two speakers will be selected in competition from the GRS that is to be held in conjunction with the main conference. New topics relative to last year's conference include spatial control of adhesion signaling, cellular niches and tissue architecture, adhesion control of cell division and polarity, and tumor cell invasion and adhesion signaling therapies. Updates on important topics such as tension sensing and signaling, cytoskeletal regulation, mechanisms of migration, and in vivo models of adhesion signaling in development are also included. Overall this international conference will showcase the major advances in the field of adhesion signaling research and will be, as it has always been, the seminal conference in the field.
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