A High-Performance Computing System for Advanced Imaging

用于高级成像的高性能计算系统

• 批准号: 8640757
• 负责人: WILLIAM D ROONEY
• 金额: $ 22.23万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8640757
• 关键词: Animals; Chemistry; Communities; Computer Systems; Data; Data Storage and Retrieval; Equipment; Four-dimensional; Funding; High Performance Computing; Image; Magnetic Resonance; Magnetic Resonance Imaging; Oregon; Physiology; Primates; Principal Investigator; Process; Research; Research Personnel; Science; Site; Structure; System; Tissues; computerized data processing; instrument; operation

DESCRIPTION: The OHSU Advanced Imaging Research Center (AIRC) was established in 2003 to provide access to state-of- the-art instruments and expert technical support in magnetic resonance science to the OHSU community. The Center now supports four high-end research-dedicated MRI instruments that includes two whole-body 3 Tesla(T) Siemens TIM Trios, a large-bore (90cm) 7T Siemens Magnetom, and a 31 cm bore 11.75T Bruker small animal instrument. Three of the instruments are located on the main OHSU campus located on Marquam Hill, overlooking downtown Portland, and one of the 3T MRI instruments is located at a satellite AIRC facility on the campus of the Oregon National Primate Research Center (ONPRC). Each of these instruments has substantial capability to generate large amounts of data. Increasingly, MRI data collected by investigators that utilize our Center is four-dimensional and demands significant storage and processing support. Such data can be very informative for understanding tissue structure, function, physiology, and chemistry. The subject of this application is to request funds for a high-performance computing system to be located at our Marquam Hill site. Our current equipment has been in operation since 2010 and supports more than 30 principal investigators, many with projects funded through federal agencies. We project that this system will be oversubscribed within the next 9 months. The proposed upgrade will substantially benefit on-going studies by providing marked increases in data storage and processing capabilities.

产品说明：OHSU高级成像研究中心（AIRC）成立于2003年，旨在为OHSU社区提供最先进的仪器和磁共振科学方面的专家技术支持。该中心现在支持四台高端研究专用MRI仪器，包括两台全身3特斯拉（T）Siemens TIM Trios，一台大口径（90 cm）7T Siemens Magnetom和一台31 cm口径11.75T Bruker小动物仪器。其中三台仪器位于位于Marquam Hill的OHSU主校区，俯瞰波特兰市中心，其中一台3T MRI仪器位于俄勒冈州国家灵长类动物研究中心（ONPRC）校园内的卫星AIRC设施。 这些工具中的每一个都具有生成大量数据的强大能力。越来越多的研究者利用我们的中心收集的MRI数据是四维的 并且需要大量的存储和处理支持。这样的数据对于理解组织结构、功能、生理学和化学可以是非常有用的。本申请的主题是请求资金用于在我们的Marquam Hill站点安装高性能计算系统。我们目前的设备自2010年以来一直在运行，并支持30多名主要研究人员，其中许多项目是由联邦机构资助的。 我们预计，该系统将在未来9个月内超额认购。 拟议的升级将大大有利于正在进行的研究，提供显着增加的数据存储和处理能力。

项目成果

Relative sensitivities of DCE-MRI pharmacokinetic parameters to arterial input function (AIF) scaling.

• DOI: 10.1016/j.jmr.2016.05.018
• 发表时间: 2016-08
• 期刊: Journal of magnetic resonance (San Diego, Calif. : 1997)
• 作者: Li X;Cai Y;Moloney B;Chen Y;Huang W;Woods M;Coakley FV;Rooney WD;Garzotto MG;Springer CS Jr
• 通讯作者: Springer CS Jr

Exploratory Study of the Brain Response in Facial Synkinesis after Bell Palsy with Systematic Review and Meta-analysis of the Literature.

对贝尔麻痹后面部联动大脑反应的探索性研究，对文献进行系统回顾和荟萃分析。

• DOI: 10.3174/ajnr.a7619
• 发表时间: 2022
• 期刊: AJNR. American journal of neuroradiology
• 作者: Krane,NA;Loyo,M;Pollock,J;Hill,M;Johnson,CZ;Stevens,AA
• 通讯作者: Stevens,AA

Nigrosome 1 absence in de novo Parkinson disease.

新发帕金森病中 Nigrosome 1 缺失。

• DOI: 10.1212/wnl.0000000000005128
• 发表时间: 2018
• 期刊: Neurology
• 影响因子: 9.9
• 作者: Brodsky,Matthew;Lahna,David;Pollock,Jeffrey;Pettersson,David;Grinstead,John;Rooney,William
• 通讯作者: Rooney,William