Asthma in Texas Healthcare Workers II

德克萨斯州医护人员的哮喘 II

• 批准号: 8747436
• 负责人: GEORGE L DELCLOS
• 金额: $ 39.13万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8747436
• 关键词: Asthma; Texas; Healthcare; Workers; II

DESCRIPTION (provided by applicant): In the U.S., asthma prevalence has grown by almost 15% and it is estimated that 15% to 25% of adult cases are caused or aggravated by work-related factors. Work-related asthma (WRA) includes asthma that is exacerbated or induced de novo by inhalation exposures in the workplace. Certain occupational groups are at an increased risk of developing WRA; among these are healthcare workers (HCWs). In 2003, we conducted the first large study of WRA in a representative sample of 5600 Texas HCWs. We found that the contribution of occupational exposure to asthma in healthcare workers was not trivial, especially among nurses, and that risk of asthma after entry into a healthcare profession was significantly increased for tasks involving instrument cleaning and disinfection, general cleaning products used on indoor building surfaces, use of powdered latex gloves, and the administration of aerosolized medications. In the 10 years that have elapsed since the survey was conducted, certain healthcare practices, such as cleaning and disinfection or administration of aerosolized medications, have changed, as has the use of certain products. It likely that these and other changes in healthcare setting practices, coupled with increased awareness of asthma in HCWs, have had an effect on WRA in this sector. Repeating the statewide survey, approximately 10 years later, drawing representative samples from the same target population but with updated and improved measures of exposure and outcomes, will allow us to document interval changes that can inform preventive policies and the design of interventions aimed at reducing the burden of WRA in HCWs. Our specific aims are to: Our specific aims are to: Aim 1: Estimate the prevalence rate of asthma risk factors and WRA in healthcare settings and compare these to rates obtained in the 2003 survey; Aim 2: Measure associations between occupational exposures and WRA among Texas HCWs and compare them to those obtained in 2003; Aim 3: Measure various indicators of socioeconomic impact of asthma in healthcare workers, comparing them among persons with WRA, non-work-related asthma and nonasthmatics.

描述（由申请人提供）：在美国，哮喘患病率增长了近15%，据估计，15%至25%的成人病例是由工作相关因素引起或加重的。工作相关性哮喘（WRA）包括因工作场所吸入暴露而加重或重新诱发的哮喘。某些职业群体发展WRA的风险增加;其中包括医疗保健工作者（HCW）。在2003年，我们进行了第一次大规模的研究，WRA的代表性样本的5600得克萨斯州HCW。我们发现，职业暴露对医护人员哮喘的贡献并不小，尤其是护士，进入医疗保健行业后，涉及仪器清洁和消毒，室内建筑表面使用的一般清洁产品，使用粉末乳胶手套和雾化药物管理的任务，哮喘的风险显着增加。自调查进行以来的10年里，某些卫生保健做法，如清洁和消毒或雾化药物的管理，已经发生变化，某些产品的使用也发生了变化。很可能这些和其他变化的医疗保健设置的做法，再加上提高认识的哮喘在医务人员，有影响的WRA在这一部门。大约10年后，重复全州范围的调查，从相同的目标人群中抽取代表性样本，但更新和改进了暴露和结果的测量，将使我们能够记录间隔变化，这些变化可以为预防政策和旨在减少HCWs WRA负担的干预措施的设计提供信息。我们的具体目标是：我们的具体目标是：目标1：估计哮喘危险因素和WRA在医疗机构中的患病率，并将其与2003年调查中获得的患病率进行比较;目标2：测量德克萨斯州HCW中职业暴露与WRA之间的关联，并将其与2003年获得的结果进行比较;目标3：测量哮喘对医护人员社会经济影响的各种指标，并与WRA患者进行比较，与工作无关的哮喘和非哮喘患者。